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US5521171A Expired / Lapsed US ⏱️ 0.0 years remaining

Anti-inflammatory and anti-ulcer compounds and process

Assignee: Individual
•
Filing: 1995-03-24
•
Granted: 1996-05-28
•
Expires: 2015-03-24
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Abstract

Abstract Disclosed herein are anti-inflammatory and anti-ulcer copper coordination compounds and a process for using them in the treatment of arthritis and gastrointestinal ulcers in animal bodies. The copper coordination compounds utilized are the reaction products of copper salts with: 1. aromatic carboxylic acids or their alkaline earth salts; 2. heterocyclic carboxylic acids or their alkaline earth salts; 3. amino acids or their alkaline earth salts; 4. amines; and 5. suitably substituted steroids. The process disclosed comprises administering to experimental animals, orally or parentrally (subcutaneously), in controlled dosages, the aforementioned copper coordination compounds for the treatment of inflammation (i.e., arthritis) and ulcers of the gastrointestinal tract.

Inventors

  • 👤 John R. J. Sorenson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 12:56
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/02; C07D231/10; C07D231/14; C07D231/28; C07D231/30; C07D231/32; C07D231/34; A; A61; A61K; A61K31/00; A61K31/60

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 44 words
A process for treating inflammation in an animal body consisting essentially of: orally or parenterally administering to said animal body an effective amount of a copper coordination compound produced by reacting a copper salt with a heterocyclic carboxylic acid or an alkaline salt thereof.
Claim 2
Dependent Claim 44 words
A process for treating inflammation in an animal body consisting essentially of: orally or parenterally administering to said animal body an effective amount of a copper coordination compound produced by reacting a copper salt with a heterocyclic carboxylic acid or an alkaline salt thereof.
Claim 3
Dependent Claim 35 words
The process of claim 1 wherein the heterocyclic acid is selected from the group consisting of 3-p-chlorophenyl-3, 4, 5, 6,-tetrahydro-β-carboline-5-carboxylic acid; 2[3(trifluoromethyl)phenyl] aminonicotinic acid; 1-carboxyisoquinoline; phenylcinchoninic acid; 2-carboxyindole, their alkaline earth salts, and mixtures thereof.
Claim 4
Dependent Claim 15 words
The process of claim 2 wherein the heterocyclic acid is 3-p-chlorophenyl-3, 4, 5, 6,-tetrahydro-β-carboline-5-carboxylic acid.
Claim 5
Dependent Claim 13 words
The process of claim 2 wherein the heterocyclic acid is 2[3(trifluoromethyl)phenyl] aminonicotinic acid.
Claim 6
Dependent Claim 11 words
The process of claim 2 wherein the heterocyclic acid is 1-carboxyisoquinoline.
Claim 7
Dependent Claim 12 words
The process of claim 2 wherein the heterocyclic acid is phenylcinchoninic acid.
Claim 8
Dependent Claim 11 words
The process of claim 2 wherein the heterocyclic acid is 2-carboxyindole.
Claim 9
Dependent Claim 24 words
The process of claim 4 wherein the copper coordination compound is administered in an amount of about 2.5-165 mg. per kilogram of body weight.

References Cited (Backward Citations)

US3758682A Cited
US3976673A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-05-28 1999-11-27 2000-05-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-05-28 2003-11-27 2004-05-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-05-28 2007-11-27 2008-05-28 $7700.00 Window Closed / Lapsed

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