US5516487A
Expired / Lapsed
US
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Absorbent paper for liquid sampling and impregnated paper calibrators and controls
Assignee: Isolab Inc
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Filing: 1994-06-22
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Granted: 1996-05-14
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Expires: 2014-06-22
Abstract
Abstract The present invention is an absorbent paper piece having a plurality of samples zones adapted to receive a liquid sample. The paper comprises an absorbent paper piece having a plurality of sample zones, each sample zone having a perforation extending substantially around its perimeter, so as to substantially obstruct the capillary flow of the liquid sample from one of the sample zones having an there sample zone adjacent thereto, to the other sample zone. It is preferred that the absorbent paper piece be provided with barrier perforations interposed between adjacent sample zones, so as to provide a gap between the sample zones as an additional capillary flow barrier. The absorbent paper piece may be adapted to hold any desired sample in liquid form such as laboratory reagents, and biological samples, such as blood samples (here used to include blood, products or components of blood, and blood hemolysate). The blood or blood products may also be arrayed in a series of sample zones for purposes of control and calibration, in accordance with practices known in the art.
Inventors
- 👤 Murray A. Rosenthal
- 👤 Vincent J. Greczanik
- 👤 Ronald A. Simkins
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 13:57
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; Y; Y10; Y10T; Y10T436/00; Y10T436/25
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
100 words
An absorbent paper piece having a plurality of sample zones adapted to receive a liquid sample, said paper piece comprising: an absorbent paper piece having a plurality of sample zones, each said sample zone defined by a respective perimeter, and each said sample zone having a perforation, said perforation comprising a series of elongated cuts, each of said cuts block capillary flow across said gap, extending substantially around said perimeter, so as to substantially obstruct the capillary flow of said liquid sample from one of said sample zones having an other sample zone adjacent thereto, to said other sample zone.
Claim 2
Dependent Claim
100 words
An absorbent paper piece having a plurality of sample zones adapted to receive a liquid sample, said paper piece comprising: an absorbent paper piece having a plurality of sample zones, each said sample zone defined by a respective perimeter, and each said sample zone having a perforation, said perforation comprising a series of elongated cuts, each of said cuts block capillary flow across said gap, extending substantially around said perimeter, so as to substantially obstruct the capillary flow of said liquid sample from one of said sample zones having an other sample zone adjacent thereto, to said other sample zone.
Claim 3
Dependent Claim
21 words
An absorbent paper piece according to claim 1 wherein said absorbent paper piece comprises a pure cotton linter, white, binderless paper.
Claim 4
Dependent Claim
49 words
An absorbent paper piece according to claim 1 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other.
Claim 5
Dependent Claim
102 words
An absorbent paper piece according to claim 1 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other, and wherein each of said at least two sample zone subseries is contained on a respective sub-part of said absorbent paper piece, each said sub-part of said absorbent paper piece having sufficiently small dimensions to allow a portion of said subpart to be punched out of each its said respective sample zone subseries.
Claim 6
Dependent Claim
21 words
An absorbent paper piece according to claim 1 wherein said plurality of sample zones comprises from 2 to 100 sample zones.
Claim 7
Dependent Claim
21 words
An absorbent paper piece according to claim 5 wherein said absorbent paper piece comprises a pure cotton linter, white, binderless paper.
Claim 8
Dependent Claim
49 words
An absorbent paper piece according to claim 5 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other.
Claim 9
Dependent Claim
102 words
An absorbent paper piece according to claim 5 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other, and wherein each of said at least two sample zone subseries is contained on a respective sub-part of said absorbent paper piece, each said sub-part of said absorbent paper piece having sufficiently small dimensions to allow a portion of said sub-part to be punched out of each its said respective sample zone subseries.
Claim 10
Dependent Claim
38 words
An absorbent paper piece according to claim 1 wherein said sample zones are of a shape selected from the group consisting of circles, ovals and ovoids, and wherein said sample zone perforation comprises a series of arcuate cuts.
Claim 11
Dependent Claim
21 words
An absorbent paper piece according to claim 9 Wherein said absorbent paper piece comprises a pure cotton linter, white, binderless paper.
Claim 12
Dependent Claim
49 words
An absorbent paper piece according to claim 9 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other.
Claim 13
Dependent Claim
102 words
An absorbent paper piece according to claim 9 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other, and wherein each of said at least two sample zone subseries is contained on a respective sub-part of said absorbent paper piece, each said sub-part of said absorbent paper piece having sufficiently small dimensions to allow a portion of said sub-part to be punched out of each its said respective sample zone subseries.
Claim 14
Dependent Claim
21 words
An absorbent paper piece according to claim 1 wherein said absorbent paper additionally comprises barrier perforations interposed between adjacent sample zones.
Claim 15
Dependent Claim
21 words
An absorbent paper piece according to claim 13 wherein said absorbent paper piece comprises a pure cotton linter, white, binderless paper.
Claim 16
Dependent Claim
49 words
An absorbent paper piece according to claim 13 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other.
Claim 17
Dependent Claim
102 words
An absorbent paper piece according to claim 13 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other, and wherein each of said at least two sample zone subseries is contained on a respective sub-part of said absorbent paper piece, each said sub-part of said absorbent paper piece having sufficiently small dimensions to allow a portion of said sub-part to be punched out of each its said respective sample zone subseries.
Claim 18
Dependent Claim
17 words
An absorbent paper piece according to claim 13 wherein said barrier perforations comprise a single elongated cut.
Claim 19
Dependent Claim
21 words
An absorbent paper piece according to claim 17 wherein said absorbent paper piece comprises a pure cotton linter, white, binderless paper.
Claim 20
Dependent Claim
49 words
An absorbent paper piece according to claim 17 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other.
Claim 21
Dependent Claim
104 words
An absorbent paper piece according to either of claim 17 wherein said plurality of sample zones is divided into at least two sample zone subseries, said at least two sample zone subseries separated by a perforation so as to allow each said sample zone subseries to be separated from each other, and wherein each of said at least two sample zone subseries is contained on a respective sub-part of said absorbent paper piece, each said sub-part of said absorbent paper piece having sufficiently small dimensions to allow a portion of said sub-part to be punched out of each its said respective sample zone subseries.
Claim 22
Dependent Claim
96 words
An absorbent paper piece having a plurality of samples zones adapted to receive a blood product sample, said paper comprising: an absorbent paper piece having a plurality of sample zones, each said sample zone defined by a respective perimeter, and each said sample zone having a perforation extending substantially around its said respective perimeter, so as to substantially obstruct the capillary flow of said blood sample from one of said sample zones having an other sample zone adjacent thereto, to said other sample zone; at least one of said sample zones containing said blood product sample.
Claim 23
Dependent Claim
96 words
An absorbent paper piece having a plurality of samples zones adapted to receive a blood product sample, said paper comprising: an absorbent paper piece having a plurality of sample zones, each said sample zone defined by a respective perimeter, and each said sample zone having a perforation extending substantially around its said respective perimeter, so as to substantially obstruct the capillary flow of said blood sample from one of said sample zones having an other sample zone adjacent thereto, to said other sample zone; at least one of said sample zones containing said blood product sample.
Claim 24
Dependent Claim
15 words
An absorbent paper piece according to claim 21 wherein said blood product sample contains sucrose.
Claim 25
Dependent Claim
37 words
An absorbent paper piece according to either of claim 22 wherein said blood sample contains sucrose present in an amount in the range of from about 0.5% to about 20% by weight of said blood product sample.
References Cited (Backward Citations)
US3346464A
Cited
US5334502A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-05-14 | 1999-11-13 | 2000-05-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-05-14 | 2003-11-13 | 2004-05-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-05-14 | 2007-11-13 | 2008-05-14 | $7700.00 | Window Closed / Lapsed |