Photosensor with multiple light sources

Claim 2

A sensor instrument for use in measuring parameters of a highly scattering medium, which comprises: a sensor head having a face for contact with the medium; a sensor carried on said head for detecting light striking a portion of said face; at least one group of light sources positioned to pass said light to said face through said medium, said light sources being of differing distances from said light sensor; and wherein all sources in each of said at least one group of sources emit light of substantially the same wavelength; a timing circuit for causing sequential illumination and shutting off of said light sources; a circuit for modulating an intensity of said light sources to provide amplitude modulated light signals at a first frequency; circuitry for providing a second signal coherent with said amplitude modulated light signals, at a second frequency, to the light sensor; circuitry for modulating the gain of, or for multiplying the output of, said light sensor by said second signal, said second frequency being different from said first frequency; and electronics for deriving a resultant signal from said light sensor while receiving said modulated light signals, said resultant signal being at a frequency of the difference between the first and second frequencies, and electronics to compute at least two of phase shift, DC, and AC components of said light signals which pass sequentially from said light sources through the medium to said light sensor.

Claim 3

The sensor instrument of claim 1 which further comprises a shield to prevent the direct access of light from said light sources to said light sensor without passing through said medium.

Claim 4

The sensor instrument of claim 1 in which a processor is provided for computing the slopes of at least two of said phase shift, DC, and AC components provided by signals from said at least one group of light sources of differing distances.

Claim 5

The sensor instrument of claim 3 in which said processor is also for computing at least one of a scattering and an absorption coefficient of the medium being measured from said slopes.

Claim 6

The sensor instrument of claim 4 in which said medium is tissue, and said processor computes absolute concentrations of at least one of oxyhemoglobin and deoxyhemoglobin present in said tissue, making use of a computed absorption coefficient, and means for display of said concentration as a real time value.

Claim 7

The sensor of claim 5, in which said at least one group of sources includes a first group that emit light of a first wavelength that is strongly absorbed by oxyhemoglobin and a second group of sources that emit light of a second, different wavelength, that is strongly absorbed by deoxyhemoglobin.

Claim 8

The sensor instrument of claim 1 in which the intensity of light from said light sources is amplitude modulated at 10-500 MHz, and the second frequency of the second signal differs from said first frequency by about 10 Hz-100 KHz.

Claim 9

The sensor of claim 1 in which one of said groups of light sources emits light having a wavelength of about 650 nm to about 1,000 nm.

Claim 10

The sensor of claim 1 in which at least three of said light sources of differing distances are present.

Claim 11

The sensor of claim 8 in which said at least one group of sources includes a first group of sources emitting light at a first wavelength and a second group of sources emitting light light at a second, different, wavelength, said groups of light sources together having at least six of said light sources, said light sources being disposed to provide pairs of light sources which are at the same distance from said sensor, to permit gathering of data at different light wavelengths.

Claim 12

The sensor instrument of claim 1 in which said electronics are also to compute at least one of a scattering coefficient and an absorption coefficient from said at least two of phase shift, DC, and AC components.

Claim 13

A sensor instrument for use in measuring parameters of body tissue, which comprises: a sensor head having a face for contact with the skin of a patient; a sensor carried on said head for detecting light striking a portion of said face; light sources positioned to pass said light to said face through said tissue, said light sources being of differing distances from said light sensor, a first group of said light sources of differing distances emitting light of one frequency and a second group of said light sources of differing distances emitting light of another frequency; a timing circuit for causing sequential illumination and shutting off of said light sources; a circuit for modulating an intensity of said light sources to provide amplitude modulated light signals at a first frequency; circuitry for providing a second signal coherent with said amplitude modulated light signals, at a second frequency, to the light sensor; circuitry for modulating the gain of, or for multiplying the output of, the light sensor by said second signal, said second frequency being different from said first frequency: electronics for deriving a resultant signal from said light sensor while receiving said modulated light signals, said resultant signal being at a frequency of the difference between the first and second frequencies; and a processor for receiving said resultant signal and determining at least two of phase shift, DC, and AC components of said light signals which pass sequentially from said light sources through the tissue to said light sensor, said processor also being for computing the slopes of said at least two of said phase shift, DC, and AC components provided by signals from said plurality of light sources of differing distances.

Claim 14

A sensor instrument for use in measuring parameters of body tissue, which comprises: a sensor head having a face for contact with the skin of a patient; a sensor carried on said head for detecting light striking a portion of said face; light sources positioned to pass said light to said face through said tissue, said light sources being of differing distances from said light sensor, a first group of said light sources of differing distances emitting light of one frequency and a second group of said light sources of differing distances emitting light of another frequency; a timing circuit for causing sequential illumination and shutting off of said light sources; a circuit for modulating an intensity of said light sources to provide amplitude modulated light signals at a first frequency; circuitry for providing a second signal coherent with said amplitude modulated light signals, at a second frequency, to the light sensor; circuitry for modulating the gain of, or for multiplying the output of, the light sensor by said second signal, said second frequency being different from said first frequency: electronics for deriving a resultant signal from said light sensor while receiving said modulated light signals, said resultant signal being at a frequency of the difference between the first and second frequencies; and a processor for receiving said resultant signal and determining at least two of phase shift, DC, and AC components of said light signals which pass sequentially from said light sources through the tissue to said light sensor, said processor also being for computing the slopes of said at least two of said phase shift, DC, and AC components provided by signals from said plurality of light sources of differing distances.

Claim 15

The sensor instrument of claim 12 in which said processor is capable of computing at least one of scattering and absorption coefficients of the tissue being measured from said slopes.

Claim 16

The sensor instrument of claim 13 in which said processor is capable of computing absolute concentrations of at least one of oxyhemoglobin and deoxyhemoglobin present in said tissue making use of said computed absorption coefficient, said sensor instrument having a display panel for displaying said concentration as a real time value.

Claim 17

The sensor instrument of claim 14, in which said first group of sources emit light of a wavelength that is strongly absorbed by oxyhemoglobin and said second group of sources emit light of a wavelength that is strongly absorbed by deoxyhemoglobin.

Claim 18

The sensor of claim 14 in which the intensity of light from said light sources is amplitude modulated at 10-500 MHz, and the second frequency of the second signal differs from said first frequency by about 10 Hz to 100 KHz.

Claim 19

The sensor instrument of claim 16 which further comprises a shield to prevent the direct access of light from said light sources to said light sensor without passing through said tissue.

Claim 20

The sensor instrument of claim 12 in which said processor is also for computing at least one of a scattering coefficient and an absorption coefficient from said slopes.

Claim 21

A sensor instrument for use in photometrically determining parameters of a highly scattering medium, which comprises: a sensor head having a face for contact with said medium; a sensor carried on said head for detecting light striking a portion of said face; at least one group of light sources positioned to pass said light to said face through said medium, said light sources being of differing distances from said light sensor; and wherein all sources in each of said at least one group of sources emit light of substantially the same wavelength; a timing circuit for causing sequential illumination and shutting off of said light sources; a circuit for modulating an intensity of said illuminated light sources to provide amplitude modulated light signals at a first frequency; electronics for providing frequency domain spectroscopy electronic processing of signals received by said sensor to provide a resultant signal which is a function of the modulated light signals received by said sensor; and a processor for receiving said resultant signal and determining at least two of phase shift, DC, and AC components of said light signals which pass sequentially from said light sources through said highly scattering media to said light sensor.

Claim 22

A sensor instrument for use in photometrically determining parameters of a highly scattering medium, which comprises: a sensor head having a face for contact with said medium; a sensor carried on said head for detecting light striking a portion of said face; at least one group of light sources positioned to pass said light to said face through said medium, said light sources being of differing distances from said light sensor; and wherein all sources in each of said at least one group of sources emit light of substantially the same wavelength; a timing circuit for causing sequential illumination and shutting off of said light sources; a circuit for modulating an intensity of said illuminated light sources to provide amplitude modulated light signals at a first frequency; electronics for providing frequency domain spectroscopy electronic processing of signals received by said sensor to provide a resultant signal which is a function of the modulated light signals received by said sensor; and a processor for receiving said resultant signal and determining at least two of phase shift, DC, and AC components of said light signals which pass sequentially from said light sources through said highly scattering media to said light sensor.

Claim 23

The sensor instrument of claim 19 in which said processor is capable of computing the slopes of at least two of said phase shift, DC, and AC components provided by light signals to said sensor from said plurality of light sources of differing distances.

Claim 24

The sensor instrument of claim 20 in which said at least one group of sources includes a first group of sources emitting light at a first wavelength and a second group of sources emitting light at a second, different, wavelength each group of said light sources emitting light at a different wavelength.

Claim 25

The sensor instrument of claim 20 in which said processor is also for determining at least one of a scattering coefficient and an absorption coefficient from said at least two of phase shift, DC, and AC components.

Claim 26

A sensor instrument for use in determining at least one of the scattering coefficient and absorption coefficient of a highly scattering medium, which comprises: a sensor head having a face for contact with the medium; a sensor carried on said head for detecting light striking a portion of said face; at least one group of light sources positioned to pass light to said face through said medium, said light sources being of differing distances from said light sensor and wherein all sources in each of said at lest one group of sources emit light of substantially the same wavelength; a timing circuit for causing sequential illumination and shutting off of said light sources; and electronics to compute at least two of phase shift, DC, and AC components of light from said light sources which has passed sequentially from said light sources through the medium to said light sensor, and to compute at least one of the scattering and absorption coefficients for said light sources.

Claim 27

A sensor instrument for use in determining at least one of the scattering coefficient and absorption coefficient of a highly scattering medium, which comprises: a sensor head having a face for contact with the medium; a sensor carried on said head for detecting light striking a portion of said face; at least one group of light sources positioned to pass light to said face through said medium, said light sources being of differing distances from said light sensor and wherein all sources in each of said at lest one group of sources emit light of substantially the same wavelength; a timing circuit for causing sequential illumination and shutting off of said light sources; and electronics to compute at least two of phase shift, DC, and AC components of light from said light sources which has passed sequentially from said light sources through the medium to said light sensor, and to compute at least one of the scattering and absorption coefficients for said light sources.

Claim 28

The sensor instrument of claim 22 in which said medium is tissue and said electronics computes absolute concentrations of at least one of oxyhemoglobin and deoxyhemoglobin present in said tissue making use of said computed absorption coefficients and their slopes; and a readout display of said concentration as a real time value.

Claim 29

The sensor of claim 23 in which one of the groups of sources emits light having a wavelength from about 650 nm to about 1000 nm.

Claim 30

The sensor of claim 23, in which said at least one group of sources includes a first group that emit light of a first wavelength that is strongly absorbed by oxyhemoglobin and a second group of sources that emit light of a second, different wavelength, that is strongly absorbed by deoxyhemoglobin.

Claim 31

A sensor instrument for use in measuring parameters of a highly scattering medium, which comprises: a sensor head having a face for contact with the medium; a sensor carried on said head for detecting light striking a portion of said face: at least one group of light sources positioned to pass said light to said face through said medium, said light sources being of differing distances from said light sensor, and wherein all sources in each of said at least one group of sources emit light of substantially the same wavelength; a timing circuit for causing sequential illumination and shutting off of said light sources; a circuit for modulating an intensity of said light sources to provide amplitude modulated light signals at a first frequency; circuitry for providing a second signal coherent with said amplitude modulated light signals, at a second frequency, to the light sensor; circuitry for modulating the gain of, or for multiplying the output of, said light sensor by said second signal, said second frequency being different from said first frequency; and electronics for deriving a resultant signal from said light sensor while receiving said modulated light signals, said resultant signal being at a frequency of the difference between the first and second frequencies, and electronics to compute at least two of phase shift, DC, and AC components of said resultant signals carrying information about the medium which is sequentially traversed through by the light signals emitted by said light sources, said electronics also being for computing at least one of a scattering coefficient and an absorption coefficient from said at least two of phase shift, DC, and AC components.

Claim 32

A sensor instrument for use in measuring parameters of a highly scattering medium, which comprises: a sensor head having a face for contact with the medium; a sensor carried on said head for detecting light striking a portion of said face: at least one group of light sources positioned to pass said light to said face through said medium, said light sources being of differing distances from said light sensor, and wherein all sources in each of said at least one group of sources emit light of substantially the same wavelength; a timing circuit for causing sequential illumination and shutting off of said light sources; a circuit for modulating an intensity of said light sources to provide amplitude modulated light signals at a first frequency; circuitry for providing a second signal coherent with said amplitude modulated light signals, at a second frequency, to the light sensor; circuitry for modulating the gain of, or for multiplying the output of, said light sensor by said second signal, said second frequency being different from said first frequency; and electronics for deriving a resultant signal from said light sensor while receiving said modulated light signals, said resultant signal being at a frequency of the difference between the first and second frequencies, and electronics to compute at least two of phase shift, DC, and AC components of said resultant signals carrying information about the medium which is sequentially traversed through by the light signals emitted by said light sources, said electronics also being for computing at least one of a scattering coefficient and an absorption coefficient from said at least two of phase shift, DC, and AC components.