US5487378A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Inhaler
Assignee: 3M Co
•
Filing: 1991-12-17
•
Granted: 1996-01-30
•
Expires: 2011-12-17
Abstract
Abstract An inhaler for dispensing droplets of liquid medicament to a patient comprising a body having a mouthpiece or nasal adaptor and a reservoir of liquid medicament in communication with an aerosol generator. The aerosol generator includes a chamber for the liquid medicament and a nozzle arrangement having a plurality of orifices. Means are provided for cyclically pressurizing the liquid medicament in the chamber such that liquid from the chamber is periodically expelled through the orifices of the nozzle arrangement as atomizer droplets of liquid medicament. Dosage control means are also provided for deactivating the aerosol generator after a predetermined time or after a predetermined volume of liquid medicament has been expelled from the chamber.
Inventors
- 👤 Paul A. Robertson
- 👤 Peter J. Houzego
- 👤 Borge R. Jensen
- 👤 Murray A. Creeke
- 👤 Neil Emerton
- 👤 Peter D. Hodson
- 👤 Eric A. Baum
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 17:22
CPC Classifications
B; B05; B05B; B05B17/00; B05B17/04; B05B17/06; B05B17/0607; B05B17/0638; A; A61; A61M; A61M15/00; A61M15/0001; A61M15/0013; A61M15/0015; A61M15/0018; A61M15/0065; A61M15/0085; B05B17/0653; B05B17/0661; B05B17/0669; B05B17/0676; A61M16/00; A61M16/0003; A61M2016/0015; A61M2016/0018; A61M2016/0024
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
169 words
An inhaler device for dispensing droplets of liquid medicament to a patient comprising a body having a mouthpiece or nasal adaptor, a reservoir of liquid medicament, and an aerosol generator in communication with said reservoir, the aerosol generator comprising a chamber for liquid medicament and a nozzle arrangement comprising a plurality of orifices in fluid flow relationship with liquid medicament in said chamber, the reservoir having walls which tend to spring to a state of maximum internal volume so as to create a slight negative head of pressure within said reservoir and said chamber, the aerosol generator further comprising means for cyclically pressurising the liquid medicament in said chamber such that liquid from said chamber is periodically expelled through the orifices as atomised droplets of liquid medicament so they may be inhaled via the mouthpiece or nasal adaptor, the inhaler device additionally comprising dosage control means for deactivating the aerosol generator after a predetermined time or after a predetermined volume of liquid medicament has been expelled from the chamber.
Claim 2
Dependent Claim
169 words
An inhaler device for dispensing droplets of liquid medicament to a patient comprising a body having a mouthpiece or nasal adaptor, a reservoir of liquid medicament, and an aerosol generator in communication with said reservoir, the aerosol generator comprising a chamber for liquid medicament and a nozzle arrangement comprising a plurality of orifices in fluid flow relationship with liquid medicament in said chamber, the reservoir having walls which tend to spring to a state of maximum internal volume so as to create a slight negative head of pressure within said reservoir and said chamber, the aerosol generator further comprising means for cyclically pressurising the liquid medicament in said chamber such that liquid from said chamber is periodically expelled through the orifices as atomised droplets of liquid medicament so they may be inhaled via the mouthpiece or nasal adaptor, the inhaler device additionally comprising dosage control means for deactivating the aerosol generator after a predetermined time or after a predetermined volume of liquid medicament has been expelled from the chamber.
Claim 3
Dependent Claim
57 words
An inhaler device as claimed in claim 1 wherein the means for cyclically pressurising the liquid medicament comprises a wall opposite the nozzle arrangement comprising a flexible portion attached to a piezo-electric element such that excitation of the piezo-electric element causes vibration of the flexible portion resulting in cyclic pressurisation of the liquid medicament in the chamber.
Claim 4
Dependent Claim
29 words
An inhaler device as claimed in claim 2 comprising means to excite the piezo-electric element at a resonant frequency within the frequency range of about 10 to 500 kHz.
Claim 5
Dependent Claim
30 words
An inhaler device as claimed in claim 2 further comprising means to excite the piezo-electric element at a resonant frequency within the frequency range of about 100 to 250 kHz.
Claim 6
Dependent Claim
30 words
An inhaler device as claimed in claim 2 further comprising means to excite the piezo-electric element at a resonant frequency within the frequency range of about 50 to 250 kHz.
Claim 7
Dependent Claim
57 words
An inhaler device as claimed in claim 1 wherein the nozzle arrangement is flexible and the means for cyclically pressurising the liquid medicament comprises a piezo-electric element associated with the flexible nozzle arrangement such that excitation of the piezo-electric element causes vibration of the nozzle arrangement resulting in cyclic pressurisation of the liquid medicament in the chamber.
Claim 8
Dependent Claim
49 words
An inhaler device as claimed in claim 6 wherein the piezo-electric element is in the form off a ring secured to a metal disc, the ring and metal disc each having a central opening to accommodate attachment of the piezo-electric element to the aerosol generator adjacent the nozzle arrangement.
Claim 9
Dependent Claim
30 words
An inhaler device as claimed in claim 7 further comprising means to excite the piezo-electric element at a resonant frequency within the frequency range of about 250 to 400 kHz.
Claim 10
Dependent Claim
30 words
An inhaler device as claimed in claim 6 further comprising means to excite the piezo-electric element at a resonant frequency within the frequency range of about 250 to 400 kHz.
Claim 11
Dependent Claim
19 words
An inhaler device as claimed in claim 1 wherein the reservoir is in the form of a collapsible bag.
Claim 12
Dependent Claim
52 words
An inhaler device as claimed in claim 1 wherein the dosage control means comprises means for measuring the volume of liquid supplied to the chamber, means for generating a signal after a predetermined volume of liquid has been measured, and means for deactivating the aerosol generator upon the generation of said signal.
Claim 13
Dependent Claim
60 words
An inhaler device as claimed in claim 11 further comprising a conduit connecting the reservoir and the chamber, the volume measuring means comprising a close fitting, free moving slug positioned in said conduit and having a density matched to that of the liquid medicament and means for detecting the position of the slug comprising optical, mechanical, or electromagnetic detection means.
Claim 14
Dependent Claim
35 words
An inhaler device as claimed in claim 12 in which the volume measuring means additionally comprises two stops for limiting movement of the slug therebetween and means for setting the slug against the upstream stop.
Claim 15
Dependent Claim
39 words
An inhaler device as claimed in claim 12 wherein the detecting means comprises means for continuously detecting the position of the slug and said signal generating means is capable of providing a signal representative of the instantaneous flow rate.
Claim 16
Dependent Claim
47 words
An inhaler device as claimed in claim 14 wherein said means for cyclically pressurising the liquid medicament comprises a piezo-electric element which vibrates said aerosol generator when excited, said inhaler device further comprising means for modulating the excitation of said piezo-electric element in accordance with said signal.
Claim 17
Dependent Claim
36 words
An inhaler device as claimed in claim 1 further comprising a breath actuation sensor for detecting a patient's inspiration through the mouthpiece or nasal adaptor and means for actuating the aerosol generator when inspiration is detected.
Claim 18
Dependent Claim
29 words
An inhaler device as claimed in claim 16 in which the breath actuation sensor comprises a pivoted vane, a flow transducer, a pressure differential transducer or a temperature sensor.
Claim 19
Dependent Claim
45 words
An inhaler device as claimed in claim 1 further comprising means for removing gas bubbles from the liquid medicament comprising a microporous material having one surface in contact with the liquid medicament and an opposite surface exposed to a region of low pressure or vacuum.
Claim 20
Dependent Claim
49 words
An inhaler device as claimed in claim 1 further comprising a venturi in communication with the mouthpiece or nasal adaptor such that the atomized droplets are directed into and substantially at right angles to the air flow generated through the venturi during inhalation through the mouthpiece or nasal adaptor.
Claim 21
Dependent Claim
75 words
An inhaler device as claimed in claim 1 wherein the inhaler device is configured as a reusable hand unit with a replaceable cartridge, said replaceable cartridge including the aerosol generator, including the nozzle arrangement and the chamber, and the reservoir as a single integral unit, a continuous passageway being formed between said reservoir and said aerosol generator so as to allow for a continuous stream of liquid medicament between said reservoir and said aerosol generator.
Claim 22
Dependent Claim
178 words
An inhaler device for dispensing droplets of liquid medicament to a patient comprising a body having a mouthpiece or nasal adaptor, a reservoir of liquid medicament, and an aerosol generator in communication with said reservoir, the aerosol generator comprising a chamber for liquid medicament and a nozzle arrangement comprising a plurality of orifices in fluid flow relationship with liquid medicament in said chamber, the aerosol generator further comprising means for cyclically pressurising the liquid medicament in said chamber such that liquid from said chamber is periodically expelled through the orifices as atomised droplets of liquid medicament so they may be inhaled via the mouthpiece or nasal adaptor, the inhaler device additionally comprising dosage control means for deactivating the aerosol generator after a predetermined time or after a predetermined volume of liquid medicament has been expelled from the chamber, the inhaler device further comprising means for removing gas bubbles from the liquid medicament comprising a microporous material having one surface in contact with the liquid medicament and an opposite surface exposed to a region of low pressure or vacuum.
Claim 23
Dependent Claim
178 words
An inhaler device for dispensing droplets of liquid medicament to a patient comprising a body having a mouthpiece or nasal adaptor, a reservoir of liquid medicament, and an aerosol generator in communication with said reservoir, the aerosol generator comprising a chamber for liquid medicament and a nozzle arrangement comprising a plurality of orifices in fluid flow relationship with liquid medicament in said chamber, the aerosol generator further comprising means for cyclically pressurising the liquid medicament in said chamber such that liquid from said chamber is periodically expelled through the orifices as atomised droplets of liquid medicament so they may be inhaled via the mouthpiece or nasal adaptor, the inhaler device additionally comprising dosage control means for deactivating the aerosol generator after a predetermined time or after a predetermined volume of liquid medicament has been expelled from the chamber, the inhaler device further comprising means for removing gas bubbles from the liquid medicament comprising a microporous material having one surface in contact with the liquid medicament and an opposite surface exposed to a region of low pressure or vacuum.
Claim 24
Dependent Claim
75 words
An inhaler device as claimed in claim 21 wherein the inhaler device is configured as a reusable hand unit with a replaceable cartridge, said replaceable cartridge including the aerosol generator, including the nozzle arrangement and the chamber, and the reservoir as a single integral unit, a continuous passageway being formed between said reservoir and said aerosol generator so as to allow for a continuous stream of liquid medicament between said reservoir and said aerosol generator.
Claim 25
Dependent Claim
57 words
An inhaler device as claimed in claim 21 wherein the nozzle arrangement is flexible and the means for cyclically pressurising the liquid medicament comprises a piezo-electric element associated with the flexible nozzle arrangement such that excitation of the piezo-electric element causes vibration of the nozzle arrangement resulting in cyclic pressurisation of the liquid medicament in the chamber.
Claim 26
Dependent Claim
49 words
An inhaler device as claimed in claim 23 wherein the piezo-electric element is in the form of a ring secured to a metal disc, the ring and metal disc each having a central opening to accommodate attachment of the piezo-electric element to the aerosol generator adjacent the nozzle arrangement.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-01-29 | 1999-07-31 | 2000-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-01-29 | 2003-07-31 | 2004-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-01-29 | 2007-07-31 | 2008-01-30 | $7700.00 | Window Closed / Lapsed |