US5478756A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Chemical sensor for detecting binding reactions
Assignee: Fisons Ltd
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Filing: 1995-02-08
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Granted: 1995-12-26
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Expires: 2015-02-08
Abstract
Abstract A chemical sensor includes a piezoelectric support (1) capable of supporting a shear horizontal wave provided on its surface with an electrode (2,3). The sensor is characterized in that the surface of the piezoelectric support (1) including the region bearing the electrode (2,3) is covered by a layer of dielectric material (9) of thickness 0.5 to 20 microns. The piezoelectric support (1) is preferably a single crystal. The dielectric layer (1) may be of, for example, silicon dioxide or a suitable polymer, and preferably has a thickness of between 0.5 and 5 μm.
Inventors
- 👤 Electra Gizeli
- 👤 Adrian C. Stevenson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 18:41
CPC Classifications
G; G01; G01N; G01N29/00; G01N29/22; G01N29/24; G01N29/2462; G01N29/02; G01N29/022; G01N2291/00; G01N2291/02; G01N2291/025; G01N2291/0256; G01N2291/04; G01N2291/042; G01N2291/0422; G01N2291/0423; Y; Y10; Y10S; Y10S436/00; Y10S436/806
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
99 words
A chemical sensor comprising: a piezoelectric support having a surface; at least two electrodes spaced apart on said surface of said piezoelectric support; a layer of dielectric material of thickness 0.5 to 20 microns applied to said surface of said piezoelectric support so as to cover at least said electrodes and a region of said surface intermediate said electrodes; and a layer of specific active reagent immobilized on said layer of dielectric material and at least intermediate said electrodes, wherein, in use of said sensor, a shear horizontal wave can be supported at said surface of said piezoelectric support.
Claim 2
Dependent Claim
99 words
A chemical sensor comprising: a piezoelectric support having a surface; at least two electrodes spaced apart on said surface of said piezoelectric support; a layer of dielectric material of thickness 0.5 to 20 microns applied to said surface of said piezoelectric support so as to cover at least said electrodes and a region of said surface intermediate said electrodes; and a layer of specific active reagent immobilized on said layer of dielectric material and at least intermediate said electrodes, wherein, in use of said sensor, a shear horizontal wave can be supported at said surface of said piezoelectric support.
Claim 3
Dependent Claim
15 words
A sensor as claimed in claim 1, wherein said piezoelectric support is a single crystal.
Claim 4
Dependent Claim
16 words
A sensor as claimed in claim 2, wherein said piezoelectric support comprises lithium tantalate or quartz.
Claim 5
Dependent Claim
31 words
A sensor as claimed in claim 1, which is a two-port waveguide sensor, wherein one of said electrodes is an input electrode and another of said electrodes is an output electrode.
Claim 6
Dependent Claim
19 words
A sensor as claimed in claim 4, wherein a metallic grating is provided between said input and output electrodes.
Claim 7
Dependent Claim
36 words
A sensor as claimed in claim 1, wherein said electrodes are photolithographically deposited on said surface as elongate regions of metallization transverse to the direction of propagation of a wave along said surface of said support.
Claim 8
Dependent Claim
23 words
A sensor as claimed in claim 6, wherein said elongate metallized regions have a width and spacing of between 1 and 40 μm.
Claim 9
Dependent Claim
19 words
A sensor as claimed in claim 1, wherein the thickness of said electrodes is between 0.1 and 5 μm.
Claim 10
Dependent Claim
45 words
A sensor as claimed in claim 1, wherein a surface of said piezoelectric support opposite to said surface carrying said electrodes is coated or intimately contacted with a material having a good impedance match with the material of said piezoelectric support and high acoustic absorption.
Claim 11
Dependent Claim
17 words
A sensor as claimed in claim 1, wherein said layer of dielectric material is of silicon dioxide.
Claim 12
Dependent Claim
15 words
A sensor as claimed in claim 1, wherein said layer of dielectric material is polymeric.
Claim 13
Dependent Claim
22 words
A sensor as claimed in claim 1, wherein the thickness of said layer of dielectric material is between 0.5 and 5 μm.
Claim 14
Dependent Claim
28 words
A sensor as claimed in claim 1, wherein said layer of dielectric material is derivatized or activated to facilitate immobilization thereon of said layer of specific active reagent.
References Cited (Backward Citations)
US4210722A
Cited
US4242096A
Cited
US4236893A
Cited
US4314821A
Cited
US4312228A
Cited
US4523122A
Cited
US4544857A
Cited
US4484098A
Cited
US4735906A
Cited
US4680499A
Cited
EP0246346A1
Cited
US4847193A
Cited
US4999284A
Cited
EP0361729A2
Cited
US5130257A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-12-25 | 1999-06-26 | 1999-12-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-12-25 | 2003-06-26 | 2003-12-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-12-25 | 2007-06-26 | 2007-12-26 | $7700.00 | Window Closed / Lapsed |