Patent DE746982C successfully refreshed from Google Patents.
US5478355A
Expired / Lapsed
US
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Method for improving the in vivo strength retention of a bioabsorbable implantable medical device and resulting medical device
Assignee: United States Surgical Corp
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Filing: 1994-12-30
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Granted: 1995-12-26
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Expires: 2014-12-30
Abstract
Abstract A method is provided for improving the in vivo strength retention of a bioabsorbable implantable medical device such as a suture.
Inventors
- 👤 Ross R. Muth
- 👤 Nagabhushanam Totakura
- 👤 Cheng-Kung Liu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:09
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/18; A61B; A61B17/00; A61B17/04; A61B17/06; A61B17/06166; A61L17/00; A61L17/06; A61L17/10; A61L31/00; A61L31/04; A61L31/06; A61B2017/0023
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
107 words
A method for improving the in vivo strength retention of a bioabsorbable implantable medical device which comprises: a) incorporating up to about 0.5 weight percent of at least one in vivo strength-retention improving, biocompatible, basic metal compound substantially uniformly within the bioabsorbable polymer from which the medical device is to be formed; and b) forming a medical device from the bioabsorbable polymer containing the basic metal compound, the medical device exhibiting about a 10 percent increase of in vivo strength retention compared to that of the same medical device formed from the bioabsorbable polymer to which no in vivo strength-retention improving basic metal compound has been incorporated.
Claim 2
Independent Claim
107 words
A method for improving the in vivo strength retention of a bioabsorbable implantable medical device which comprises: a) incorporating up to about 0.5 weight percent of at least one in vivo strength-retention improving, biocompatible, basic metal compound substantially uniformly within the bioabsorbable polymer from which the medical device is to be formed; and b) forming a medical device from the bioabsorbable polymer containing the basic metal compound, the medical device exhibiting about a 10 percent increase of in vivo strength retention compared to that of the same medical device formed from the bioabsorbable polymer to which no in vivo strength-retention improving basic metal compound has been incorporated.
Claim 3
Dependent Claim
14 words
The method of claim 1 wherein the basic metal compound is an organic compound.
Claim 4
Dependent Claim
14 words
The method of claim 1 wherein the basic metal compound is an inorganic compound.
Claim 5
Dependent Claim
23 words
The method of claim 1 wherein the basic metal compound is a metal oxide, metal hydroxide, metal carbonate, metal phosphate or metal halide.
Claim 6
Dependent Claim
38 words
The method of claim 1 wherein the basic metal compound is calcium oxide, calcium hydroxide, calcium carbonate, calcium phosphate, calcium fluoride, magnesium oxide, magnesium hydroxide, magnesium carbonate, magnesium phosphate, sodium phosphate, sodium fluoride, potassium phosphate and potassium fluoride.
Claim 7
Dependent Claim
25 words
The method of claim 1 wherein the basic metal compound is present in an amount less than about 0.2 weight percent of the bioabsorbable polymer.
Claim 8
Dependent Claim
25 words
The method of claim 1 wherein the in vivo strength retention of the bioabsorbable implantable medical device is increased by at least about 20 percent.
Claim 9
Dependent Claim
33 words
The method of claim 1 wherein the bioabsorbable polymer is derived from one or more monomers selected from the group consisting of glycolide, glycolic acid, lactide, lactic acid, ε-caprolactone, p-dioxanone and trimethylene carbonate.
Claim 10
Dependent Claim
28 words
The method of claim 1 wherein the medical device is selected from a group consisting of a surgical suture, staple, clip, pin, screw, ring, implant and prosthetic device.
Claim 11
Dependent Claim
25 words
The method of claim 1 wherein the bioabsorbable polymer is a copolymer derived from glycolide and lactide and the medical device is a surgical suture.
Claim 12
Dependent Claim
46 words
A polymeric bioabsorbable surgical suture containing an in vivo strength retention-improving amount of up to about 0.5 weight percent of at least one in vivo strength-retaining biocompatible basic metal compound which is substantially uniformly incorporated within the bioabsorbable polymer from which the surgical suture is made.
Claim 13
Dependent Claim
46 words
A polymeric bioabsorbable surgical suture containing an in vivo strength retention-improving amount of up to about 0.5 weight percent of at least one in vivo strength-retaining biocompatible basic metal compound which is substantially uniformly incorporated within the bioabsorbable polymer from which the surgical suture is made.
Claim 14
Dependent Claim
16 words
The bioabsorbable surgical suture of claim 11 wherein the basic metal compound is an organic compound.
Claim 15
Dependent Claim
16 words
The bioabsorbable surgical suture of claim 11 wherein the basic metal compound is an inorganic compound.
Claim 16
Dependent Claim
25 words
The bioabsorbable surgical suture of claim 11 wherein the basic metal compound is a metal oxide, metal hydroxide, metal carbonate, metal phosphate or metal halide.
Claim 17
Dependent Claim
40 words
The bioabsorbable surgical suture of claim 11 wherein the basic metal compound is calcium oxide, calcium hydroxide, calcium carbonate, calcium phosphate, calcium fluoride, magnesium oxide, magnesium hydroxide, magnesium carbonate, magnesium phosphate, sodium phosphate, sodium fluoride, potassium phosphate and potassium fluoride.
Claim 18
Dependent Claim
27 words
The bioabsorbable surgical suture of claim 11 wherein the basic metal compound is present in an amount less than about 0.2 weight percent of the bioabsorbable polymer.
Claim 19
Dependent Claim
12 words
The bioabsorbable surgical suture of claim 11 which is of braided construction.
Claim 20
Dependent Claim
24 words
The bioabsorbable surgical suture of claim 11 wherein the in vivo strength retention of the suture is improved by at least about 10 percent.
Claim 21
Dependent Claim
24 words
The bioabsorbable surgical suture of claim 11 wherein the in vivo strength retention of the suture is improved by at least about 20 percent.
Claim 22
Dependent Claim
41 words
The bioabsorbable surgical suture of claim 11 wherein the bioabsorbable polymer from which the suture is made is derived from one or more monomers selected from the group consisting of glycolide, glycolic acid, lactide, lactic acid, ε-caprolactone, p-dioxanone and trimethylene carbonate.
Claim 23
Dependent Claim
40 words
The bioabsorbable surgical suture of claim 11 containing from about 0.05 to about 0.25 weight percent of in vivo strength retention-improving basic metal compound to increase the in vivo strength retention of the suture by at least about 10 percent.
Claim 24
Dependent Claim
47 words
The bioabsorbable surgical suture of claim 21 which is of braided construction and wherein the bioabsorbable polymer from which the suture is made is derived from one or more monomers selected from the group consisting of glycolide, glycolic acid, lactide, lactic acid, ε-caprolactone, p-dioxanone and trimethylene carbonate.
Claim 25
Dependent Claim
25 words
The bioabsorbable surgical suture of claim 21 wherein the basic metal compound is a metal oxide, metal hydroxide, metal carbonate, metal phosphate or metal halide.
Claim 26
Dependent Claim
40 words
The bioabsorbable surgical suture of claim 21 wherein the basic metal compound is calcium oxide, calcium hydroxide, calcium carbonate, calcium phosphate, calcium fluoride, magnesium oxide, magnesium hydroxide, magnesium carbonate, magnesium phosphate, sodium phosphate, sodium fluoride, potassium phosphate and potassium fluoride.
Claim 27
Dependent Claim
44 words
A bioabsorbable polymer containing an in vivo strength retention-improving amount of up to about 0.5 weight percent of at least one in vivo strength-retaining biocompatible basic metal compound which is substantially uniformly incorporated within the bioabsorbable polymer from which the surgical suture is made.
Claim 28
Dependent Claim
44 words
A bioabsorbable polymer containing an in vivo strength retention-improving amount of up to about 0.5 weight percent of at least one in vivo strength-retaining biocompatible basic metal compound which is substantially uniformly incorporated within the bioabsorbable polymer from which the surgical suture is made.
Claim 29
Dependent Claim
15 words
The bioabsorbable polymer of claim 25 wherein the basic metal compound is an organic compound.
Claim 30
Dependent Claim
15 words
The bioabsorbable polymer of claim 25 wherein the basic metal compound is an inorganic compound.
Claim 31
Dependent Claim
24 words
The bioabsorbable polymer of claim 25 wherein the basic metal compound is a metal oxide, metal hydroxide, metal carbonate, metal phosphate or metal halide.
Claim 32
Dependent Claim
39 words
The bioabsorbable polymer of claim 25 wherein the basic metal compound is calcium oxide, calcium hydroxide, calcium carbonate, calcium phosphate, calcium fluoride, magnesium oxide, magnesium hydroxide, magnesium carbonate, magnesium phosphate, sodium phosphate, sodium fluoride, potassium phosphate and potassium fluoride.
Claim 33
Dependent Claim
26 words
The bioabsorbable polymer of claim 25 wherein the basic metal compound is present in an amount less than about 0.2 weight percent of the bioabsorbable polymer.
Claim 34
Dependent Claim
23 words
The bioabsorbable polymer of claim 25 wherein the in vivo strength retention of the suture is improved by at least about 10 percent.
Claim 35
Dependent Claim
23 words
The bioabsorbable polymer of claim 25 wherein the in vivo strength retention of the suture is improved by at least about 20 percent.
Claim 36
Dependent Claim
40 words
The bioabsorbable polymer of claim 25 wherein the bioabsorbable polymer from which the suture is made is derived from one or more monomers selected from the group consisting of glycolide, glycolic acid, lactide, lactic acid, ε-caprolactone, p-dioxanone and trimethylene carbonate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-12-25 | 1999-06-26 | 1999-12-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-12-25 | 2003-06-26 | 2003-12-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-12-25 | 2007-06-26 | 2007-12-26 | $7700.00 | Window Closed / Lapsed |