US5429134A
Expired / Lapsed
US
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Multi-phase fat suppressed MRI cardiac imaging
Assignee: General Electric Co
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Filing: 1994-06-27
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Granted: 1995-07-04
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Expires: 2014-06-27
Abstract
Abstract Fast NMR pulse sequences are employed to acquire data in a single breath-hold from which a plurality of cardiac phase images are reconstructed. Signals from fat are suppressed by frequency selective RF inversion pulses applied just prior to each group of fast NMR pulse sequences.
Inventors
- 👤 Thomas K. Foo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:23
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/567; G01R33/5673; G01R33/5607; G01R33/563; G01R33/56308
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
208 words
A method for acquiring NMR data from a patient during a succession of cardiac cycles from which a plurality of cardiac phase images can be reconstructed, the steps comprising: a) producing a cardiac signal which indicates cardiac phase of the patient during each cardiac cycle; b) applying to the patient in timed relation with the cardiac signal a first, frequency selective, RF inversion pulse tuned to fat and having a first flip angle; c) applying a first group of NMR pulse sequences and acquiring NMR data for a first cardiac phase image during an interval following the first frequency selective, RF inversion pulse in which NMR signals produced by fat are minimal; d) applying to the patient in timed relation with the cardiac signal a second, frequency selective, RF inversion pulse tuned to fat and having a second flip angle; e) applying a second group of NMR pulse sequences and acquiring NMR data for a second cardiac phase image during an interval following the second frequency selective, RF inversion pulse in which NMR signals produced by fat are minimal; wherein the first flip angle of the first frequency selective, RF inversion pulse is substantially less than the second flip angle of the second frequency selective, RF inversion pulse.
Claim 2
Independent Claim
208 words
A method for acquiring NMR data from a patient during a succession of cardiac cycles from which a plurality of cardiac phase images can be reconstructed, the steps comprising: a) producing a cardiac signal which indicates cardiac phase of the patient during each cardiac cycle; b) applying to the patient in timed relation with the cardiac signal a first, frequency selective, RF inversion pulse tuned to fat and having a first flip angle; c) applying a first group of NMR pulse sequences and acquiring NMR data for a first cardiac phase image during an interval following the first frequency selective, RF inversion pulse in which NMR signals produced by fat are minimal; d) applying to the patient in timed relation with the cardiac signal a second, frequency selective, RF inversion pulse tuned to fat and having a second flip angle; e) applying a second group of NMR pulse sequences and acquiring NMR data for a second cardiac phase image during an interval following the second frequency selective, RF inversion pulse in which NMR signals produced by fat are minimal; wherein the first flip angle of the first frequency selective, RF inversion pulse is substantially less than the second flip angle of the second frequency selective, RF inversion pulse.
Claim 3
Dependent Claim
38 words
The method as recited in claim 1 in which the flip angle of the second frequency selective, RF inversion pulse is approximately 180°, and the flip angle of the first frequency selective, RF inversion pulse is approximately 120°.
Claim 4
Dependent Claim
19 words
The method as recited in claim 1 in which the NMR pulse sequences are fast gradient echo pulse sequences.
Claim 5
Dependent Claim
26 words
The method as recited in claim 1 in which each group of NMR pulse sequences includes eight NMR pulse sequences that acquire eight separate NMR signals.
Claim 6
Dependent Claim
57 words
The method as recited in claim 1 in which each NMR pulse sequence in each of said groups of NMR pulse sequences includes an RF excitation pulse having a flip angle, and further includes applying each RF excitation pulse to the patient and separately acquiring a NMR signal as a result of the applied RF excitation pulse.
Claim 7
Dependent Claim
36 words
The method as recited in claim 5 which includes separately determining the flip angle of each RF excitation pulse such that the acquired NMR signals have amplitudes which are substantially independent of fluctuations in longitudinal magnetization.
Claim 8
Dependent Claim
62 words
The method as recited in claim 5 in which each NMR pulse sequence in each of said groups of NMR pulse sequences includes applying to the patient a magnetic field gradient pulse that position encodes the acquired NMR signal, and further applying magnetic field gradient pulses to the patient during intervals of the cardiac cycle during which no NMR data is acquired.
Claim 9
Dependent Claim
35 words
The method as recited in claim 5 which includes reconstructing a first cardiac phase image using the NMR data acquired by said first group of NMR pulse sequences over a plurality of successive cardiac cycles.
Claim 10
Dependent Claim
36 words
The method as recited in claim 8 which includes applying a phase encoding gradient pulse during each NMR pulse sequence having a value ranging from low levels for central views to high levels for peripheral views.
Claim 11
Dependent Claim
35 words
The method as recited in claim 9 which includes ordering the views such that a set of central views are acquired by the same NMR pulse sequence in each of a succession of cardiac cycles.
Claim 12
Dependent Claim
32 words
The method as recited in claim 1 which includes repeating steps d) and e) as many times as possible within the cardiac cycle to acquire NMR data for additional cardiac phase images.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-07-03 | 1999-01-02 | 1999-07-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-07-03 | 2003-01-02 | 2003-07-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-07-03 | 2007-01-02 | 2007-07-04 | $7700.00 | Window Closed / Lapsed |