US5424288A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of treating solid tumor cancers utilizing macro aggregated proteins and colloidal radioactive phosphorous
Assignee: Molecular Radiation Management Inc
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Filing: 1994-01-26
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Granted: 1995-06-13
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Expires: 2014-01-26
Abstract
Abstract A method of treating solid tumor cancer in a living being by prolonging the time a therapeutically effective agent remains in the tumor. The method comprises the steps of selecting particles of an aggregated protein and injecting them interstitially into the tumor. The therapeutically effective agent colloidal radioactive phosphorous is injected into the tumor either after the injection of the proteinaceous particles, or simultaneously.
Inventors
- 👤 Stanley E. Order
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 05:54
CPC Classifications
A; A61; A61K; A61K51/00; A61K51/12; A61K51/1217; A61K47/00; A61K47/50; A61K47/69; A61K47/6921; A61K47/6927; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1658; A61K2121/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
74 words
A method of treating solid tumor cancer in a living being, the method comprising the steps of: (a) selecting particles of macroaggregated albumin having an approximate diameter of 10 to 150 micrometers and wherein not less than 90 percent of the particles are approximately 10 to 90 microns in size; (b) injecting at least 2,000,000 of the particles into the tumor; and (c) then injecting colloidal radioactive chromic phosphate 32 P into the tumor.
Claim 2
Independent Claim
74 words
A method of treating solid tumor cancer in a living being, the method comprising the steps of: (a) selecting particles of macroaggregated albumin having an approximate diameter of 10 to 150 micrometers and wherein not less than 90 percent of the particles are approximately 10 to 90 microns in size; (b) injecting at least 2,000,000 of the particles into the tumor; and (c) then injecting colloidal radioactive chromic phosphate 32 P into the tumor.
Claim 3
Dependent Claim
23 words
The method of claim 1 additionally comprising selecting the number of particles to be injected into the tumor to be at least 2,500,000.
Claim 4
Independent Claim
105 words
A method of treating solid tumor cancer in a living being by enabling colloidal radioactive chromic phosphate 32 P to remain in contact with the cancerous tissue to permit colloidal radioactive chromic phosphate 32 P to be taken up by the cancer, the method comprising the steps of: (a) selecting particles of macroaggregated albumin having an approximate diameter of 10 to 150 micrometers and wherein not less than 90 percent of the particles are approximately 10 to 90 microns in size; (b) injecting at least 2,000,000 particles of the albumin into the tumor; and (c) injecting colloidal radioactive chromic phosphate 32 P into the tumor.
Claim 5
Independent Claim
105 words
A method of treating solid tumor cancer in a living being by enabling colloidal radioactive chromic phosphate 32 P to remain in contact with the cancerous tissue to permit colloidal radioactive chromic phosphate 32 P to be taken up by the cancer, the method comprising the steps of: (a) selecting particles of macroaggregated albumin having an approximate diameter of 10 to 150 micrometers and wherein not less than 90 percent of the particles are approximately 10 to 90 microns in size; (b) injecting at least 2,000,000 particles of the albumin into the tumor; and (c) injecting colloidal radioactive chromic phosphate 32 P into the tumor.
References Cited (Backward Citations)
USRE33375E
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-06-12 | 1998-12-12 | 1999-06-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-06-12 | 2002-12-12 | 2003-06-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-06-12 | 2006-12-12 | 2007-06-13 | $7700.00 | Window Closed / Lapsed |