US5401237A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Blood processing for treating blood disease
Assignee: Individual
•
Filing: 1992-06-26
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Granted: 1995-03-28
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Expires: 2012-06-26
Abstract
Abstract A method and an apparatus for an effective chemical treatment of a blood disease apply a drug of a wider range with a smaller dose or lower concentration to the blood outside the patient's body. Blood which is collected from a patient is fed through a tube (2a) into a chamber (4) by a pump (3). A drug is injected into the chamber (4) from a container (5), while ultrasonic waves are applied to the blood contained in the chamber (4) from an actuator (7). The blood treated with the drug and by the ultrasonic waves, is returned into the body of the patient through a tube (2c), while the same is monitored by sensors (10) and (11).
Inventors
- 👤 Shunro Tachibana
- 👤 Ichiro Sogawa
- 👤 Katsuro Tachibana
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 02:32
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/36; A61M1/3687; H; H04; H04R; H04R17/00; H04R17/04; H04R17/08
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
75 words
An apparatus for processing blood, comprising a passage having an inlet and an outlet for passing blood therethrough; a pump for feeding said blood from said inlet toward said outlet in said passage; drug injection means for injecting a drug into said passage; and ultrasonic wave application means for improving an effectiveness of said drug on a component of said blood by applying ultrasonic waves to said blood mixed with said drug in said passage.
Claim 2
Independent Claim
75 words
An apparatus for processing blood, comprising a passage having an inlet and an outlet for passing blood therethrough; a pump for feeding said blood from said inlet toward said outlet in said passage; drug injection means for injecting a drug into said passage; and ultrasonic wave application means for improving an effectiveness of said drug on a component of said blood by applying ultrasonic waves to said blood mixed with said drug in said passage.
Claim 3
Dependent Claim
24 words
The apparatus in accordance with claim 1, further comprising a treatment sensor for monitoring relevant blood characteristics of said blood discharged from said passage.
Claim 4
Dependent Claim
27 words
The apparatus in accordance with claim 1, further comprising removal means for removing said drug from said blood flowing in said passage after injection of said drug.
Claim 5
Dependent Claim
36 words
The apparatus in accordance with claim 1, wherein said passage comprises a tube for introducing said blood, and a chamber connected with said tube for mixing said blood with said drug while applying ultrasonic waves therein.
Claim 6
Dependent Claim
46 words
The apparatus in accordance with claim 4, wherein said ultrasonic wave application means comprise an ultrasonic transmission element provided in said chamber, an ultrasonic transmission control circuit outside said chamber, and means connecting said ultrasonic transmission element to said ultrasonic transmission control circuit outside said chamber.
Claim 7
Dependent Claim
18 words
The apparatus in accordance with claim 1, as applied to an external circulation system for treating a patient.
Claim 8
Independent Claim
65 words
A method for processing blood, comprising: (a) feeding blood into a treatment passage at a treatment rate; (b) adding a quantity of a drug to said blood in said passage; (c) applying ultrasonic waves to said blood containing said drug in said treatment passage, for improving an effectiveness of said drug on a component of said blood; and (d) discharging ultrasonic-treated blood from said passage.
Claim 9
Independent Claim
65 words
A method for processing blood, comprising: (a) feeding blood into a treatment passage at a treatment rate; (b) adding a quantity of a drug to said blood in said passage; (c) applying ultrasonic waves to said blood containing said drug in said treatment passage, for improving an effectiveness of said drug on a component of said blood; and (d) discharging ultrasonic-treated blood from said passage.
Claim 10
Dependent Claim
21 words
The method in accordance with claim 7, further comprising monitoring treatment relevant characteristics of said blood discharged from said treatment passage.
Claim 11
Dependent Claim
25 words
The method in accordance with claim 7, further comprising removing said drug left in said blood before discharge of said blood from said treatment passage.
Claim 12
Dependent Claim
33 words
The method of claim 7, wherein said blood is whole blood and said blood is not separated during any step of said method, wherein said ultrasonic waves are applied to said whole blood.
Claim 13
Dependent Claim
18 words
The method of claim 7, wherein said blood is not heated above normal body temperatures during said method.
Claim 14
Dependent Claim
16 words
The method of claim 7, wherein said blood component is a component other than red cells.
Claim 15
Dependent Claim
12 words
The method of claim 12, wherein said blood component is lymphocytic cells.
Claim 16
Independent Claim
61 words
A method of treating a patient having a blood disease, said method comprising: (a) collecting blood from said patient; (b) adding a drug to said collected blood; (c) applying ultrasonic waves to said blood containing said drug for improving an effectiveness of said drug on a component of said blood; and (d) returning ultrasonic-treated blood into the body of said patient.
Claim 17
Independent Claim
61 words
A method of treating a patient having a blood disease, said method comprising: (a) collecting blood from said patient; (b) adding a drug to said collected blood; (c) applying ultrasonic waves to said blood containing said drug for improving an effectiveness of said drug on a component of said blood; and (d) returning ultrasonic-treated blood into the body of said patient.
Claim 18
Dependent Claim
49 words
The method in accordance with claim 14, further comprising correlating a definite volume of said blood continuously collected from said patient to a prescription dose of said drug and to a prescription dose of said ultrasonic waves, and then continuously returning treated blood into the body of said patient.
Claim 19
Dependent Claim
35 words
The method in accordance with claim 14, further comprising removing said drug still left in said blood after said application of ultrasonic waves and before said blood is returned into the body of said patient.
Claim 20
Dependent Claim
17 words
The method in accordance with claim 14, further comprising monitoring said ultrasonic-treated blood for treatment relevant characteristics.
Claim 21
Dependent Claim
15 words
The method in accordance with claim 14, wherein a disease of said blood is leukemia.
Claim 22
Dependent Claim
14 words
The method in accordance with claim 14, wherein said drug includes a carcinostatic substance.
Claim 23
Dependent Claim
14 words
The method in accordance with claim 18, wherein said drug includes a carcinostatic substance.
Claim 24
Dependent Claim
33 words
The method of claim 14, wherein said blood is whole blood and said blood is not separated during any step of said method, wherein said ultrasonic waves are applied to said whole blood.
Claim 25
Dependent Claim
18 words
The method of claim 14, wherein said blood is not heated above normal body temperatures during said method.
Claim 26
Dependent Claim
16 words
The method of claim 14, wherein said blood component is a component other than red cells.
Claim 27
Dependent Claim
12 words
The method of claim 23, wherein said blood component is lymphocytic cells.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-03-27 | 1998-09-26 | 1999-03-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-03-27 | 2002-09-26 | 2003-03-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-03-27 | 2006-09-26 | 2007-03-28 | $7700.00 | Window Closed / Lapsed |