US5397353A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Implant tissue
Assignee: Covidien AG
•
Filing: 1991-01-03
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Granted: 1995-03-14
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Expires: 2011-01-03
Abstract
Abstract A collagenous tissue preparation suitable for homotransplantation or heterotransplantion. The preparation is a non-resorbable, non-antigenic collagenous material which retains the natural structure and original architecture of the natural tissue. The material is substantially free of non-fibrous tissue proteins, glycoproteins, cellular elements and lipids. The tissue preparation is recolonized by host cells and revascularized after implantation into the host.
Inventors
- 👤 Roy F. Oliver
- 👤 Roy A. Grant
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:43
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3683; A61L27/3695; C; C08; C08H; C08H1/00; C08H1/06
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
93 words
A non-resorbable, substantially non-antigenic collagenous fibrous tissue preparation of human or animal tissue origin, which is suitable for homo- or heterotransplantation as a permanent repair for cutaneous wounds and soft tissue injuries, which preparation retains the natural structure and original architecture of said human or animal tissue, is substantially free of non-fibrous tissue proteins and glycoproteins, is substantially free of cellular elements, is substantially free of lipids and lipid residues and is non-cytotoxic, wherein said preparation is capable when implanted of being recolonized by host cells and revascularized while being resistant to calcification.
Claim 2
Dependent Claim
93 words
A non-resorbable, substantially non-antigenic collagenous fibrous tissue preparation of human or animal tissue origin, which is suitable for homo- or heterotransplantation as a permanent repair for cutaneous wounds and soft tissue injuries, which preparation retains the natural structure and original architecture of said human or animal tissue, is substantially free of non-fibrous tissue proteins and glycoproteins, is substantially free of cellular elements, is substantially free of lipids and lipid residues and is non-cytotoxic, wherein said preparation is capable when implanted of being recolonized by host cells and revascularized while being resistant to calcification.
Claim 3
Dependent Claim
15 words
A preparation as claimed in claim 1 additionally substantially free of antigenic polysaccharides and mucopolysaccharides.
Claim 4
Dependent Claim
18 words
A preparation as claimed in any one of the preceding claims when in the form of a sheet.
Claim 5
Dependent Claim
28 words
An implant for the permanent repair of cutaneous or soft tissue injuries in humans which comprises a sheet of substantially non-antigenic collageneous fibrous tissue preparation of claim 1.
Claim 6
Dependent Claim
16 words
An implant as claimed in claim 4 in which the implant is derived from pig dermis.
Claim 7
Dependent Claim
33 words
An implant as claimed in either of claims 4 or 5 in which the implant is formed from a sheet of fibrous collagenous tissue which has been cross-linked by means of a polyisocyanate.
Claim 8
Dependent Claim
14 words
An implant as claimed in claim 6 in which the polyisocyanate is hexamethylene diisocyanate.
References Cited (Backward Citations)
GB964545A
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GB995357A
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US3318774A
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FR1317581A
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US3873478A
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US4060081A
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GB1565340A
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GB2079797A
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US4378224A
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US4420339A
Cited
US4357274A
Cited
US4801299A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-03-13 | 1998-09-12 | 1999-03-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-03-13 | 2002-09-12 | 2003-03-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-03-13 | 2006-09-12 | 2007-03-14 | $7700.00 | Window Closed / Lapsed |