US5395831A
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US
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Treating cardiac disorders with Δ9(11)-dehydro-8-isoestrone
Assignee: Wyeth LLC
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Filing: 1994-04-08
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Granted: 1995-03-07
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Expires: 2014-04-08
Abstract
Abstract This invention relates to 8α-3-hydroxyestra- 1,3,5( 10),9( 11 )tetraen-17-one (Δ9( 11 )-dehydro-8-isoestrone) (VI), ##STR1## to the process for its preparation, to pharmaceutical compositions containing said 8α-3-hydroxyestra- 1,3,5(10), 9(11)tetraen-17-one (Δ9(11)-dehydro-8-isoestrone) (VI) and to the use of said 8α-3-hydroxyestra-1,3,5(10),9(11 )tetraen-17-one (A9( 11 )-dehydro-8-isoestrone) (VI) for modifying the balance between bone production and bone resorption, and as an antioxidant in a host animal, including man.
Inventors
- 👤 Frederick O. Gemmill, Jr.
- 👤 Chester E. Orzech
- 👤 Steven J. Adelman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 02:42
CPC Classifications
C; C07; C07J; C07J1/00; A; A61; A61K; A61K31/00; A61K31/56; A61K31/565; A61P; A61P19/00; A61P19/08; A61P19/10; A61P9/00; A61P9/10; C07J1/0051; C07J1/0059; C07J15/00
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
19 words
A method of treating atherosclerosis in a mammal which comprises administering an effective amount of Δ9(11)-dehydro-8-isoestrone to said mammal.
Claim 2
Independent Claim
19 words
A method of treating atherosclerosis in a mammal which comprises administering an effective amount of Δ9(11)-dehydro-8-isoestrone to said mammal.
Claim 3
Independent Claim
22 words
A method of treating coronary artery disease in a mammal which comprises administering an effective amount of a Δ9(11)-dehydro-8-isoestrone to said mammal.
Claim 4
Independent Claim
22 words
A method of treating coronary artery disease in a mammal which comprises administering an effective amount of a Δ9(11)-dehydro-8-isoestrone to said mammal.
References Cited (Backward Citations)
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US3649621A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-03-06 | 1998-09-05 | 1999-03-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-03-06 | 2002-09-05 | 2003-03-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-03-06 | 2006-09-05 | 2007-03-07 | $7700.00 | Window Closed / Lapsed |