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US5387589A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of treating ocular inflammation

Assignee: University of Louisville Research Foundation ULRF
•
Filing: 1992-11-17
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Granted: 1995-02-07
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Expires: 2012-11-17
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Abstract

Abstract Disclosed is a method of treating ocular inflammation in a mammal in need of such treatment, including administering to the mammal an anti-inflammatory amount of rapamycin.

Inventors

  • 👤 Prasad S. Kulkarni

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 13:28
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/33; A61K31/335; A61K31/365; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61P; A61P27/00; A61P27/02; A61P29/00

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 25 words
A method for treating ocular inflammation in a mammal in need of said treatment, comprising administering to said mammal an effective anti-inflammatory amount of rapamycin.
Claim 2
Independent Claim 25 words
A method for treating ocular inflammation in a mammal in need of said treatment, comprising administering to said mammal an effective anti-inflammatory amount of rapamycin.
Claim 3
Dependent Claim 39 words
The method according to claim 1 in which said ocular inflammation is selected from the group consisting of uveitis, conjunctivitis, episcleritis, scleritis, optic neuritis, retrobulbar neuritis, ocular inflammation following ocular surgery, and ocular inflammation resulting from physical eye trauma.
Claim 4
Dependent Claim 28 words
The method of claim 1, wherein said rapamycin is administered by a route of administration selected from the group consisting of oral, parenteral, topical, transdermal and rectal administration.
Claim 5
Independent Claim 33 words
A method of providing symptomatic relief of, preventing the progression of, or eradicating ocular inflammation in a mammal in need of thereof, comprising administering to said mammal an effective anti-inflammatory amount of rapamycin.
Claim 6
Independent Claim 33 words
A method of providing symptomatic relief of, preventing the progression of, or eradicating ocular inflammation in a mammal in need of thereof, comprising administering to said mammal an effective anti-inflammatory amount of rapamycin.
Claim 7
Independent Claim 27 words
A method for treating ocular inflammation in a mammal in need of said treatment, comprising administering to said mammal between about 0.01 and 50 mg/kg/day of rapamycin.
Claim 8
Independent Claim 27 words
A method for treating ocular inflammation in a mammal in need of said treatment, comprising administering to said mammal between about 0.01 and 50 mg/kg/day of rapamycin.
Claim 9
Dependent Claim 20 words
The method of claim 5 wherein said rapamycin is administered in an amount of between about 0.1 to 35 mg/kg/day.
Claim 10
Dependent Claim 20 words
The method of claim 5 wherein said rapamycin is administered in an amount of between about 0.3 to 25 mg/kg/day.

References Cited (Backward Citations)

US3929992A Cited
US3993749A Cited
US4885171A Cited
US5066493A Cited
US4316885A Cited
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EP0406791A2 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1998-02-06 1998-08-08 1999-02-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2002-02-06 2002-08-08 2003-02-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2006-02-06 2006-08-08 2007-02-07 $7700.00 Window Closed / Lapsed

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