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US5380272A Expired / Lapsed US ⏱️ 0.0 years remaining

Transcutaneous drug delivery applicator

Assignee: Scientific Innovations Ltd
•
Filing: 1993-06-16
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Granted: 1995-01-10
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Expires: 2013-06-16
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Abstract

Abstract A transcutaneous iontophoretic drug applicator, which includes an array of reservoirs which are electrically insulated from one another, some of which contain the drug to be administered. The applicator further includes a partially electrically conducting layer, preferably formed of two portions, each segments corresponding to an electrode, which overlies and contacts the reservoirs, and electrodes which overly and contact the partially electrically conducting layer. An electrical power source supplies power to the electrodes and causes the drug to be pushed out of the reservoirs and into the skin. The applicator is designed to keep the local current flux below threshold irritation and burn levels regardless of variations in electrical skin resistance.

Inventors

  • 👤 Joseph Gross

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 04:30
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0428; A61N1/0432; A61N1/044; A61N1/0448

Claims Analysis

Total Claims: 19
Claim 1
Independent Claim 88 words
A transcutaneous iontophoretic chemical applicator for applying a chemical, comprising: (a) an array of reservoirs, said reservoirs being electrically insulated from one another, at least one of said reservoirs containing the chemical; (b) a partially electrically conducting layer overlying and contacting at least two of said reservoirs, said partially electrically conducting layer being made up of a single layer overlying all of said reservoirs; (c) electrodes overlying and physically and electrically contacting said partially electrically conducting layer; and (d) an electrical power source electrically connected to said electrodes.
Claim 2
Dependent Claim 88 words
A transcutaneous iontophoretic chemical applicator for applying a chemical, comprising: (a) an array of reservoirs, said reservoirs being electrically insulated from one another, at least one of said reservoirs containing the chemical; (b) a partially electrically conducting layer overlying and contacting at least two of said reservoirs, said partially electrically conducting layer being made up of a single layer overlying all of said reservoirs; (c) electrodes overlying and physically and electrically contacting said partially electrically conducting layer; and (d) an electrical power source electrically connected to said electrodes.
Claim 3
Dependent Claim 19 words
An applicator as in claim 1, wherein said electrodes include a single positive electrode and a single negative electrode.
Claim 4
Dependent Claim 27 words
An applicator as in claim 1, wherein said electrodes include a plurality of pairs of electrodes, each of said electrodes overlying at least one of said reservoirs.
Claim 5
Dependent Claim 14 words
An applicator as in claim 1, wherein said reservoirs contain an electrically conducting material.
Claim 6
Dependent Claim 29 words
An applicator as in claim 1, wherein said partially electrically conducting layer is made up of at least two segments, each of said segments overlying some of said reservoirs.
Claim 7
Dependent Claim 29 words
An applicator as in claim 2, wherein said partially electrically conducting layer is made up of at least two segments, each of said segments overlying some of said reservoirs.
Claim 8
Dependent Claim 16 words
An applicator as in claim 1, wherein said partially electrically conducting layer includes a semiconducting material.
Claim 9
Dependent Claim 19 words
An applicator as in claim 7, wherein said partially electrically conducting layer includes silicon and further includes carbon particles.
Claim 10
Dependent Claim 23 words
An applicator as in claim 1, wherein said reservoirs are a plurality of regularly shaped volumes integrally formed of electrically insulating material layer.
Claim 11
Dependent Claim 22 words
An applicator as in claim 1, wherein said reservoirs are a plurality of microporous volumes integrally formed of electrically insulating material layer.
Claim 12
Dependent Claim 13 words
An applicator as in claim 9, wherein said electrically insulating material includes silicon.
Claim 13
Dependent Claim 13 words
An applicator as in claim 10, wherein said electrically insulating material includes silicon.
Claim 14
Dependent Claim 16 words
An applicator as in claim 1, wherein said electrical power source is a layer power source.
Claim 15
Dependent Claim 22 words
An applicator as in claim 1, further comprising a removable seal covering said array of reservoirs which is removed prior to deployment.
Claim 16
Dependent Claim 16 words
An applicator as in claim 14 wherein the removal of said removable seal exposes an adhesive.
Claim 17
Dependent Claim 20 words
An applicator as in claim 15 wherein said adhesive is located on the exposed surfaces of said array of reservoirs.
Claim 18
Dependent Claim 95 words
A transdermal drug applicator for applying a drug, comprising: (a) an array of reservoirs, one or more of which contain the drug, said reservoirs being integrally formed in an electrically insulating layer; (b) a partially electrically conducting layer located above and in contact with said reservoirs, said partially electrically conducting layer being made up of a single layer overlying all of said reservoirs; (c) a pair of electrodes located above and in physical and electrical contact with said partially electrically conducting layer; and (d) an electrical power source electrically connected to said pair of electrodes.
Claim 19
Dependent Claim 95 words
A transdermal drug applicator for applying a drug, comprising: (a) an array of reservoirs, one or more of which contain the drug, said reservoirs being integrally formed in an electrically insulating layer; (b) a partially electrically conducting layer located above and in contact with said reservoirs, said partially electrically conducting layer being made up of a single layer overlying all of said reservoirs; (c) a pair of electrodes located above and in physical and electrical contact with said partially electrically conducting layer; and (d) an electrical power source electrically connected to said pair of electrodes.

References Cited (Backward Citations)

US4708716A Cited
US4883457A Cited
US4731926A Cited
US4865582A Cited
US5002527A Cited
US5053001A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1998-01-09 1998-07-11 1999-01-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2002-01-09 2002-07-11 2003-01-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2006-01-09 2006-07-11 2007-01-10 $7700.00 Window Closed / Lapsed

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