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US5375600A Expired / Lapsed US ⏱️ 0.0 years remaining

Ultrasonic frequency-domain system and method for sensing fluid flow

Assignee: HP Inc
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Filing: 1993-08-09
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Granted: 1994-12-27
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Expires: 2013-08-09
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Abstract

Abstract Pulses of ultrasound are focused in the patient's body to create an interrogation volume where a characteristic of blood flow is to be measured. The bandwidth of the back-scattered Doppler return signal is measured. In order to measure flow velocity independent of direction, the interrogation volume is generated substantially as a sphere in which the range dimension is set equal to the lateral dimensions (azimuth and elevation) of the interrogation signal. The Doppler bandwidth is then scaled to provide a direction-independent measurement of flow velocity. In order to determine the direction of flow, the interrogation volume is generated substantially as an ellipsoid. The long axis of the ellipsoidal interrogation volume is then rotated until the measured Doppler bandwidth is at a minimum, which is reached when the long axis is aligned with the flow direction. The interrogation volume is preferably rotated and translated using differential phasing of the ultrasonic signals from different transducer elements in a two-dimensional array.

Inventors

  • 👤 Hewlett E. Melton, Jr.
  • 👤 King-Wah W. Yeung
  • 👤 Michael Greenstein

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 20:34
CPC Classifications
G; G01; G01S; G01S15/00; G01S15/88; G01S15/89; G01S15/8906; G01S15/8979; G01S15/8984; A; A61; A61B; A61B8/00; A61B8/06; A61B8/48; A61B8/488; G01S15/02; G01S15/50; G01S15/58; G01S15/582

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 197 words
A method for measuring blood flow within a blood vessel or organ comprising the following steps: A. repeatedly applying to each of a plurality of piezoelectric transducer elements a corresponding pulsed electrical transmit signal; B. in the transducer elements, sensing a receive signal that is back-scattered from blood within the blood vessel or organ; C. electrically shaping and phasing the transmit and receive signals to generate a substantially spherical and isotropic interrogation region within which blood flow is to be measured; D. for each application of the pulsed electrical excitation signals, sensing an ultrasonic return signal that is back-scattered from particles within the interrogation region; E. converting the sensed ultrasonic return signals into a corresponding composite electrical return signal; F. measuring Doppler shift of the composite electrical return signal and generating a corresponding detected Doppler signal; G. measuring the bandwidth of the detected Doppler signal; H. determining a proportionality factor that is proportional to a beam width of the interrogation region; and I. outputting a representation of a magnitude of flow velocity as a predetermined function of the measured bandwidth of the detected Doppler signal, the predetermined function comprising scaling the beam width by the proportionality factor.
Claim 2
Independent Claim 197 words
A method for measuring blood flow within a blood vessel or organ comprising the following steps: A. repeatedly applying to each of a plurality of piezoelectric transducer elements a corresponding pulsed electrical transmit signal; B. in the transducer elements, sensing a receive signal that is back-scattered from blood within the blood vessel or organ; C. electrically shaping and phasing the transmit and receive signals to generate a substantially spherical and isotropic interrogation region within which blood flow is to be measured; D. for each application of the pulsed electrical excitation signals, sensing an ultrasonic return signal that is back-scattered from particles within the interrogation region; E. converting the sensed ultrasonic return signals into a corresponding composite electrical return signal; F. measuring Doppler shift of the composite electrical return signal and generating a corresponding detected Doppler signal; G. measuring the bandwidth of the detected Doppler signal; H. determining a proportionality factor that is proportional to a beam width of the interrogation region; and I. outputting a representation of a magnitude of flow velocity as a predetermined function of the measured bandwidth of the detected Doppler signal, the predetermined function comprising scaling the beam width by the proportionality factor.
Claim 3
Dependent Claim 46 words
A method as defined in claim 1, in which the step of shaping and phasing the electrical transmit and receive signals includes generating the transmit and receive signals with a range dimension of the interrogation region substantially equal to an elevational dimension and an azimuthal dimension.
Claim 4
Dependent Claim 97 words
A method as defined in claim 1, in which the predetermined blood flow characteristic is the direction of blood flow, comprising the following additional steps: A. shaping and phasing the electrical transmit and receive signals to the transducer elements so that the interrogation region is substantially ellipsoidal with a long axis; B. generating a plurality of the ellipsoidal interrogation regions with different directions of their respective long axes; and C. outputting as the representation of the flow direction the direction of the long axis of the ellipsoidal interrogation region for which the measured bandwidth is a minimum.
Claim 5
Dependent Claim 35 words
A method as defined in claim 3, in which the step of shaping and phasing the transmit and receive signals includes differential phasing of a plurality of transducer elements arranged as a two-dimensional phased array.
Claim 6
Independent Claim 210 words
A method for measuring the magnitude of velocity of blood flow in a blood vessel or organ comprising the following steps: A. repeatedly applying to each of a plurality of piezoelectric transducer elements a corresponding pulsed electrical transmit signal; B. in the transducer elements, sensing a receive signal that is back-scattered from blood within the blood vessel or organ; C. electrically shaping and phasing the transmit and receive signals to generate a substantially spherical and isotropic interrogation region within which blood flow is to be measured, with a range dimension of an interrogation region substantially equal to an elevational dimension and an azimuthal dimension; D. for each application of the pulsed electrical transmit and receive signals, sensing an ultrasonic return signal that is back-scattered from particles within the interrogation region; E. converting the sensed ultrasonic return signals into a corresponding composite electrical return signal; F. determining a proportionality factor that is proportional to a beam width of the interrogation region; G. measuring Doppler shift of the composite electrical return signal and generating a corresponding detected Doppler signal; H. measuring the bandwidth of the detected Doppler signal; and I. outputting a representation of a predetermined blood flow characteristic as a predetermined function of the measured bandwidth of the detected Doppler signal.
Claim 7
Independent Claim 210 words
A method for measuring the magnitude of velocity of blood flow in a blood vessel or organ comprising the following steps: A. repeatedly applying to each of a plurality of piezoelectric transducer elements a corresponding pulsed electrical transmit signal; B. in the transducer elements, sensing a receive signal that is back-scattered from blood within the blood vessel or organ; C. electrically shaping and phasing the transmit and receive signals to generate a substantially spherical and isotropic interrogation region within which blood flow is to be measured, with a range dimension of an interrogation region substantially equal to an elevational dimension and an azimuthal dimension; D. for each application of the pulsed electrical transmit and receive signals, sensing an ultrasonic return signal that is back-scattered from particles within the interrogation region; E. converting the sensed ultrasonic return signals into a corresponding composite electrical return signal; F. determining a proportionality factor that is proportional to a beam width of the interrogation region; G. measuring Doppler shift of the composite electrical return signal and generating a corresponding detected Doppler signal; H. measuring the bandwidth of the detected Doppler signal; and I. outputting a representation of a predetermined blood flow characteristic as a predetermined function of the measured bandwidth of the detected Doppler signal.
Claim 8
Independent Claim 188 words
A system for measuring blood flow within a blood vessel or organ comprising: A. an ultrasonic transducer with a plurality of piezoelectric transducer elements forming transducer means for generating a substantially spherical and isotropic ultrasonic interrogation region within which the blood flows; B. timing and signal excitation and sensing means for repeatedly applying to each of the transducer elements a corresponding pulsed electrical transmit signal, for sensing a receive signal that is back-scattered to the transducer elements from blood within the blood vessel or organ, and for electrically shaping and phasing the transmit and receive signals to generate the interrogation region; C. Doppler bandwidth detection means for detecting a bandwidth of a composite Doppler return signal corresponding to back-scattered return signals that have been back-scattered by particles in the blood; and D. processing means for generating a representation of a a magnitude of flow velocity as a predetermined function of the measured bandwidth of the detected Doppler signal, and for generating the representation of the magnitude of velocity by scaling the measured bandwidth by a proportionality factor, which is proportional to a beam width of the interrogation region.
Claim 9
Independent Claim 188 words
A system for measuring blood flow within a blood vessel or organ comprising: A. an ultrasonic transducer with a plurality of piezoelectric transducer elements forming transducer means for generating a substantially spherical and isotropic ultrasonic interrogation region within which the blood flows; B. timing and signal excitation and sensing means for repeatedly applying to each of the transducer elements a corresponding pulsed electrical transmit signal, for sensing a receive signal that is back-scattered to the transducer elements from blood within the blood vessel or organ, and for electrically shaping and phasing the transmit and receive signals to generate the interrogation region; C. Doppler bandwidth detection means for detecting a bandwidth of a composite Doppler return signal corresponding to back-scattered return signals that have been back-scattered by particles in the blood; and D. processing means for generating a representation of a a magnitude of flow velocity as a predetermined function of the measured bandwidth of the detected Doppler signal, and for generating the representation of the magnitude of velocity by scaling the measured bandwidth by a proportionality factor, which is proportional to a beam width of the interrogation region.
Claim 10
Independent Claim 224 words
A system for measuring blood flow within a blood vessel or organ comprising: A. an ultrasonic transducer with a plurality of piezoelectric transducer elements forming transducer means for generating an ultrasonic interrogation region within which the blood flows, in which the interrogation region is substantially ellipsoidal with a long axis; B. timing and signal excitation and sensing means for repeatedly applying to each of the transducer elements a corresponding pulsed electrical transmit signal, for sensing a receive signal that is back-scattered to the transducer elements from blood within the blood vessel or organ, and for electrically shaping and phasing the transmit and receive signals to generate the interrogation region; C. Doppler bandwidth detection means for detecting a bandwidth of a composite Doppler return signal corresponding to back-scattered return signals that have been back-scattered by particles in the blood; and D. processing means: 1) for generating a representation of the direction of blood flow as a predetermined function of the measured bandwidth of the detected Doppler signal; 2) for controlling the timing and signal excitation and sensing means for generating a plurality of the ellipsoidal interrogation regions with different directions of their respective long axes; and 3) for outputting as the representation of the flow direction the direction of the long axis of the ellipsoidal interrogation region for which the measured bandwidth is a minimum.
Claim 11
Independent Claim 224 words
A system for measuring blood flow within a blood vessel or organ comprising: A. an ultrasonic transducer with a plurality of piezoelectric transducer elements forming transducer means for generating an ultrasonic interrogation region within which the blood flows, in which the interrogation region is substantially ellipsoidal with a long axis; B. timing and signal excitation and sensing means for repeatedly applying to each of the transducer elements a corresponding pulsed electrical transmit signal, for sensing a receive signal that is back-scattered to the transducer elements from blood within the blood vessel or organ, and for electrically shaping and phasing the transmit and receive signals to generate the interrogation region; C. Doppler bandwidth detection means for detecting a bandwidth of a composite Doppler return signal corresponding to back-scattered return signals that have been back-scattered by particles in the blood; and D. processing means: 1) for generating a representation of the direction of blood flow as a predetermined function of the measured bandwidth of the detected Doppler signal; 2) for controlling the timing and signal excitation and sensing means for generating a plurality of the ellipsoidal interrogation regions with different directions of their respective long axes; and 3) for outputting as the representation of the flow direction the direction of the long axis of the ellipsoidal interrogation region for which the measured bandwidth is a minimum.
Claim 12
Dependent Claim 20 words
A system as defined in claim 7, in which the transducer elements are as arranged as a two-dimensional phased array.

References Cited (Backward Citations)

US5156153A Cited
US5249577A Cited
US5121364A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-12-26 1998-06-27 1998-12-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-12-26 2002-06-27 2002-12-27 $3760.00 Window Closed / Lapsed
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