US5368027A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sensor arrangement for direct or indirect optical determination of physical or chemical properties
Assignee: AVL Medical Instruments AG
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Filing: 1993-04-07
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Granted: 1994-11-29
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Expires: 2013-04-07
Abstract
Abstract In a sensor arrangement for direct or indirect optical determination of physical or chemical parameters, in human and animal bodies, the sensor arrangement including an indicator cell which is permeable to the chemical substance or physical quantity to be measured and which contains one or more indicators, a radiation source supplying the excitation radiation for the indicator, and a detector for detection of the response radiation emitted by the indicator, the indicator cell is configured as a capsule which may be introduced into body cavities, such as mouth, nose, stomach, intestine, blood vessels, bronchial tubes, urinary bladder, or which may be implanted in the tissue, and the material used for this capsule is transparent to excitation radiation and to the response radiation emitted by the indicator in the range of wavelengths between 600 and 1,300 nm, and the material of the capsule, or rather, its outer layer, is bio-compatible.
Inventors
- 👤 Dietrich W. Lubbers
- 👤 Hellfried Karpf
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 21:29
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14539; A61B5/1455; A61B5/1459; A61B5/42; A61B5/41; A61B5/413
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
163 words
A sensor arrangement for direct or indirect optical determination of physical or chemical parameters, comprising a radiation source supplying an excitation radiation for at least one indicator, a detector means for detection of a response radiation emitted by said indicator, in which contact between said radiation source and said indicator, and between said indicator and said detector, is exclusively established via said excitation radiation and said response radiation, and an indicator cell which comprises a capsule which is introduceable into body cavities, such as mouth, nose, stomach, intestine, blood vessels, bronchial tubes, urinary bladder, or which is implantable in the tissue, said capsule being permeable to a chemical substance or physical quantity to be measured, and at least one indicator in said capsule, wherein material used for said capsule is transparent to said excitation radiation and to said response radiation in the range of wavelengths between 600 and 1,300 nm, and wherein at least an outer layer of said capsule material is biocompatible.
Claim 2
Dependent Claim
163 words
A sensor arrangement for direct or indirect optical determination of physical or chemical parameters, comprising a radiation source supplying an excitation radiation for at least one indicator, a detector means for detection of a response radiation emitted by said indicator, in which contact between said radiation source and said indicator, and between said indicator and said detector, is exclusively established via said excitation radiation and said response radiation, and an indicator cell which comprises a capsule which is introduceable into body cavities, such as mouth, nose, stomach, intestine, blood vessels, bronchial tubes, urinary bladder, or which is implantable in the tissue, said capsule being permeable to a chemical substance or physical quantity to be measured, and at least one indicator in said capsule, wherein material used for said capsule is transparent to said excitation radiation and to said response radiation in the range of wavelengths between 600 and 1,300 nm, and wherein at least an outer layer of said capsule material is biocompatible.
Claim 3
Dependent Claim
23 words
A sensor according to claim 1, wherein said capsule is of essentially one of a spherical, lenticular and cylindrical shape with rounded edges.
Claim 4
Dependent Claim
18 words
A sensor arrangement according to claim 2, wherein at least one said capsule is attached on a string.
Claim 5
Dependent Claim
19 words
A sensor arrangement according to claim 2, wherein a plurality of said capsules are attached to a two-dimensional network.
Claim 6
Dependent Claim
20 words
A sensor arrangement according to claim 1, wherein said capsule is configured as one of a string- and tube-like structure.
Claim 7
Dependent Claim
16 words
A sensor arrangement according to claim 1, wherein said capsule is configured as a sheet-like structure.
Claim 8
Dependent Claim
12 words
A sensor arrangement according to claim 1, wherein said capsule is sterilizable.
Claim 9
Dependent Claim
29 words
A sensor arrangement according to claim 1, wherein said capsule is provided with particles permitting its localization inside the body by one of optical means, ultrasonic techniques, and X-rays.
Claim 10
Dependent Claim
28 words
A sensor arrangement according to claim 1, wherein said capsule is provided with at least one reflecting surface which is positioned adjacent to said at least one indicator.
Claim 11
Dependent Claim
28 words
A sensor arrangement according to claim 1, wherein said capsule is provided with at least one reflecting surface which is positioned adjacent to a layer containing said indicator.
Claim 12
Dependent Claim
19 words
A sensor arrangement according to claim 1, wherein said indicator inside said capsule is embedded in a hydrogel layer.
Claim 13
Dependent Claim
25 words
A sensor arrangement according to claim 1, wherein said capsule is made of polymer material transparent in the wave range between 600 and 1,300 nm.
Claim 14
Dependent Claim
16 words
A sensor arrangement according to claim 12, wherein said capsule is made of a dialytic membrane.
Claim 15
Dependent Claim
24 words
A sensor arrangement according to claim 1, wherein said capsule is made of glass transparent in the wave range between 600 and 1,300 nm.
Claim 16
Dependent Claim
47 words
A sensor arrangement according to claim 1, wherein said at least one indicator in said capsule is provided for measuring at least one physical or chemical parameter from a group consisting of ionic concentration, partial gas pressure, concentration of enzyme or substrate, ionic strength, pressure, and temperature.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-11-28 | 1998-05-30 | 1998-11-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-11-28 | 2002-05-30 | 2002-11-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-11-28 | 2006-05-30 | 2006-11-29 | $7700.00 | Window Closed / Lapsed |