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US5363697A Expired / Lapsed US ⏱️ 0.0 years remaining

Scanning probe microscope, molecular processing method using the scanning probe microscope and DNA base arrangement detecting method

Assignee: Panasonic Holdings Corp
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Filing: 1992-04-29
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Granted: 1994-11-15
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Expires: 2012-04-29
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Abstract

Abstract This invention relates to a scanning probe microscope which examines or processes directly the structure of substance surfaces at the molecular or atomic level, and a method for processing molecules using a scanning probe microscope and a method for detecting DNA base arrangement. A scanning probe microscope has a probe approaching or contacting the substance surface to detect a physical quantity between the substance surface and the probe, wherein the physical quantity is what is interacted or chemically reacted between the substance surface and the molecules or atom groups which act as a sensor and are fixed on the probe, scanning at an atomic level of precision. Therefore, surface structure within a microscopic region can be examined or processed at the molecular or atomic level. A method for detecting DNA base arrangement with any one of three or four kinds of probes fixed with any one of four different kinds of molecules interacting four kinds of bases consisting of DNA, by approaching single stranded DNA fixed on a substrate, measuring the force and scanning by an atomic force microscope at an atomic level of precision.

Inventors

  • 👤 Tohru Nakagawa

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 00:12
CPC Classifications
G; G01; G01Q; G01Q60/00; G01Q60/60; B; B82; B82Y; B82Y35/00; G01Q60/24; G01Q60/38; G01Q60/42; B82Y30/00; Y; Y10; Y10S; Y10S977/00; Y10S977/70; Y10S977/724; Y10S977/727; Y10S977/728; Y10S977/84; Y10S977/849; Y10S977/852; Y10S977/853; Y10S977/86; Y10S977/875; Y10S977/877; Y10S977/879; Y10S977/88; Y10S977/881; Y10S977/902; Y10S977/904; Y10S977/924; Y10S977/932; Y10S977/953; Y10S977/957; Y10S977/958

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 73 words
A scanning probe microscope comprising a probe approaching or contacting a substance surface to detect a physical quantity between the substance surface and the probe, wherein the physical quantity is what is interacted or chemically reacted between the substance surface and molecules or atom groups which act as a sensor are fixed on the probe to form a chemically adsorbed monomolecular film, and the probe is scanned at an atomic level of precision.
Claim 2
Dependent Claim 73 words
A scanning probe microscope comprising a probe approaching or contacting a substance surface to detect a physical quantity between the substance surface and the probe, wherein the physical quantity is what is interacted or chemically reacted between the substance surface and molecules or atom groups which act as a sensor are fixed on the probe to form a chemically adsorbed monomolecular film, and the probe is scanned at an atomic level of precision.
Claim 3
Dependent Claim 29 words
The scanning probe microscope according to claim 1, wherein the scanning probe microscope is an atomic force microscope and the physical quantity to be detected is an atomic force.
Claim 4
Dependent Claim 79 words
A scanning probe microscope comprising a probe approaching or contacting a substance surface to detect a physical quantity between the substance surface and the probe wherein the probe is separated and transferred to approach or contact the substance surface repeatedly, and wherein the physical quantity is what is interacted or chemically reacted between the substance surface and molecules or atom groups which act as a sensor and are fixed on the probe to form a chemically adsorbed monomolecular film.
Claim 5
Dependent Claim 79 words
A scanning probe microscope comprising a probe approaching or contacting a substance surface to detect a physical quantity between the substance surface and the probe wherein the probe is separated and transferred to approach or contact the substance surface repeatedly, and wherein the physical quantity is what is interacted or chemically reacted between the substance surface and molecules or atom groups which act as a sensor and are fixed on the probe to form a chemically adsorbed monomolecular film.
Claim 6
Dependent Claim 29 words
The scanning probe microscope according to claim 3, wherein the scanning probe microscope is an atomic force microscope and the physical quantity to be detected is an atomic force.
Claim 7
Independent Claim 55 words
A method for processing molecules of a substance surface at the molecular or atomic level comprising strongly interacting or chemically reacting molecules or atom groups fixed to the scanning probe to form a chemically adsorbed monomolecular film, and detecting a physical quantity which is measured through the probe by approaching or contacting the substance surface.
Claim 8
Independent Claim 55 words
A method for processing molecules of a substance surface at the molecular or atomic level comprising strongly interacting or chemically reacting molecules or atom groups fixed to the scanning probe to form a chemically adsorbed monomolecular film, and detecting a physical quantity which is measured through the probe by approaching or contacting the substance surface.
Claim 9
Dependent Claim 41 words
The method according to claim 5, wherein the molecules are processed with an atomic force microscope and the physical quantity being interacted between molecules or atom groups which are fixed on the probe and the substance surface is an atomic force.

References Cited (Backward Citations)

US4724318A Cited
JPS63304103A Cited
US4868396A Cited
EP0397416A1 Cited
GB2235049A Cited
EP0404682A2 Cited
EP0410618A2 Cited
US5144833A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-11-14 1998-05-16 1998-11-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-11-14 2002-05-16 2002-11-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-11-14 2006-05-16 2006-11-15 $7700.00 Window Closed / Lapsed

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