US5360893A
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DNA sequences encoding proteins used to elicit and detect programmed cell death
Assignee: University of Colorado Foundation Inc
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Filing: 1992-07-20
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Granted: 1994-11-01
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Expires: 2012-07-20
Abstract
Abstract Polypeptides and mutants and variants associated with programmed cell death in mammalian cells and DNA sequences, and fragments and derivatives thereof, encoding the polypeptides are disclosed. Also disclosed are methods for detecting programmed cell death in mammalian cells, a method of activating programmed cell death in unwanted mammalian cells, and methods for preventing unwanted cell death occurring in degenerative disorders of mammals.
Inventors
- 👤 Gregory P. Owens
- 👤 J. John Cohen
- 👤 William E. Hahn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 22:15
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/46; C07K14/47; C07K14/4701; C07K14/4747; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
38 words
A polypeptide in substantially pure form and mutants and variants of the polypeptide eliciting programmed mammalian cell death, wherein the amino acid sequence is coded for by the DNA sequence set out in FIG. 5 (SEQ ID NO:1).
Claim 2
Dependent Claim
38 words
A polypeptide in substantially pure form and mutants and variants of the polypeptide eliciting programmed mammalian cell death, wherein the amino acid sequence is coded for by the DNA sequence set out in FIG. 5 (SEQ ID NO:1).
Claim 3
Dependent Claim
38 words
A polypeptide in substantially pure form and mutants and variants of the polypeptide eliciting programmed mammalian cell death, wherein the amino acid sequence is coded for by the DNA sequence set out in FIG. 6 (SEQ ID NO:3).
Claim 4
Dependent Claim
38 words
A polypeptide in substantially pure form and mutants and variants of the polypeptide eliciting programmed mammalian cell death, wherein the amino acid sequence is coded for by the DNA sequence set out in FIG. 6 (SEQ ID NO:3).
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-10-31 | 1998-05-02 | 1998-11-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-10-31 | 2002-05-02 | 2002-11-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-10-31 | 2006-05-02 | 2006-11-01 | $7700.00 | Window Closed / Lapsed |