In situ apparatus for generating an electrical current in a biological environment

Claim 2

Apparatus for the in situ generation of an electrical current in a biological environment including electrically conductive tissue and an electrolyte, said current generation apparatus comprising first and second layers of electrically conductive materials of different electrochemical potentials and an insulating third layer intermediate and contiguous said first and second layers, each of said layers having a passage therethrough into which proximate conductive tissue cells can expand to bridge said first and second layers, whereby said apparatus, when immersed in the electrolyte, generates electrolytically an electrical current through the bridging conductive tissue cells.

Claim 3

Apparatus for the in situ generation of electrical current as recited in claim 1 wherein each of the materials of said first, second and third layers are selected from a group that are compatible with the biological environment including the conductive tissue and the electrolytes.

Claim 4

Apparatus for the in situ generation of electrical current as recited in claim 2 wherein said first and second layers are materials selected from the group consisting of iron, tantalum and silver and an aluminum magnesium alloy.

Claim 5

Apparatus for the in situ generation of electrical current as recited in claim 3 wherein said first and second layers are formed of iron and tantalum respectively.

Claim 6

Apparatus for the in situ generation of electrical current as recited in claim 3 wherein said first and second layers are formed of silver and tantalum respectively.

Claim 7

Apparatus for the in situ generation of electrical current as recited in claim 3 wherein said first and second layers are formed of an aluminum magnesium alloy and tantalum respectively.

Claim 8

Apparatus for the in situ generation of electrical current as recited in claim 2 wherein said insulating layer is inert in the biological environment.

Claim 9

Apparatus for the in situ generation of electrical current as recited in claim 7 wherein said insulating layer is a polymer.

Claim 10

Apparatus for the in situ generation of electrical current as recited in claim 7 wherein said conductive layers and insulating layer are foraminous and collectively form a permeable membrane.

Claim 11

Apparatus for the in situ generation of electrical current as recited in claim 2 wherein said first, second and third layers collectively form a planar apparatus.

Claim 12

Apparatus for the in situ generation of electrical current as recited in claim 2 wherein said first, second and third layers collectively form a substantially tubular structure.

Claim 13

Apparatus for the in situ generation of electrical current as recited in claim 11 wherein at least one of said first and second layers provides a self-supporting structure.

Claim 14

A stent assembly for insertion in a vessel having a boundary vessel wall with tissue cells and containing an electrolytic fluid comprising, as a nested structure: A. an inner stent formed of a conductive material with a first electrochemical potential, B. an outer stent formed of a conductive material with a second electrochemical potential that differs from the first electrochemical potential, and C. an intermediate insulating means for electrically isolating said inner and outer stents from each other, said stent assembly, in a vessel, having a passage therethrough into which proximate conductive cells can expand, and forming an electrolytic generator when the electrolytic fluid in the vessel contacts said stent assembly and when the conductive tissue cells form a conductive path bridging said inner and outer stents.

Claim 15

A stent assembly for insertion in a vessel having a boundary vessel wall with tissue cells and containing an electrolytic fluid comprising, as a nested structure: A. an inner stent formed of a conductive material with a first electrochemical potential, B. an outer stent formed of a conductive material with a second electrochemical potential that differs from the first electrochemical potential, and C. an intermediate insulating means for electrically isolating said inner and outer stents from each other, said stent assembly, in a vessel, having a passage therethrough into which proximate conductive cells can expand, and forming an electrolytic generator when the electrolytic fluid in the vessel contacts said stent assembly and when the conductive tissue cells form a conductive path bridging said inner and outer stents.

Claim 16

A stent assembly as recited in claim 13 wherein said stents are composed from materials selected from the group consisting of aluminum, silver, iron, tantalum and alloy of aluminum magnesium.

Claim 17

A stent assembly as recited in claim 14 wherein one of said stents is formed of iron and the other of said stents is formed of tantalum whereby said tantalum comprises a cathode and said iron comprises an anode.

Claim 18

A stent assembly as recited in claim 14 wherein one of said stents is formed of silver and the other of said stents is formed of tantalum whereby said tantalum comprises a cathode and said silver comprises an anode.

Claim 19

A stent assembly as recited in claim 14 wherein one of said stents is formed of a tantalum filament in an open mesh, self-supporting structure.

Claim 20

A stent assembly as recited in claim 14 wherein said insulating layer is composed of a polymer.

Claim 21

A stent assembly as recited in claim 14 wherein said insulating means is composed of polyethylene.

Claim 22

A stent assembly as recited in claim 13 wherein each of said stents and insulating means are foraminous.

Claim 25

A method as recited in claim 21 wherein the multiple layer structure comprises multiple sheets, said method additionally comprising the steps of locating the sheets proximate existent hyperplastic cells and forming the sheets to conform the multiple layer structure to the profile of the hyperplastic cells.

Claim 26

A method as recited in claim 21 wherein the first and second layers are formed of concentric tubular structures separated by a tubular insulating member, said method additionally comprising locating the multi-layer structure in tubular form at the walls of the vessel.

Claim 27

A method as recited in claim 23 wherein at least one of the layers is formed of loosely interlocked knitted loops of a metal filament and said multi-layer structure is adapted for being compacted to a small radial size for introduction lengthwise into the vessel, said method additionally comprising the step of expanding the multi-layer structure to engage the vessel walls.

Claim 28

Apparatus for the in situ generation of an electrical current in an electrically conductive biological environment with an electrolyte, said current generation apparatus comprising first and second foraminous layers of electrically conductive materials of different electrochemical potentials and a foraminous insulating third layer intermediate said first and second layers whereby said first and second layers, when immersed in the electrolyte become coupled conductively to the biological environment and generate electrolytically an electrical current for transfer through the biological environment.

Claim 29

Apparatus for the in situ generation of an electrical current in an electrically conductive biological environment with an electrolyte, said current generation apparatus comprising first and second foraminous layers of electrically conductive materials of different electrochemical potentials and a foraminous insulating third layer intermediate said first and second layers whereby said first and second layers, when immersed in the electrolyte become coupled conductively to the biological environment and generate electrolytically an electrical current for transfer through the biological environment.

Claim 30

Apparatus for the in situ generation of electrical current as recited in claim 25 wherein each of the materials of said first, second and third layers are selected from a group that are compatible with the biological environment and the electrolytes in that environment.

Claim 31

Apparatus for the in situ generation of electrical current as recited in claim 25 wherein said first and second layers are materials selected from the group consisting of iron, tantalum and silver and an aluminum magnesium alloy.

Claim 32

Apparatus for the in situ generation of electrical current as recited in claim 27 wherein said first and second layers are formed of iron and tantalum respectively.

Claim 33

Apparatus for the in situ generation of electrical current as recited in claim 27 wherein said first and second layers are formed of silver and tantalum respectively.

Claim 34

Apparatus for the in situ generation of electrical current as recited in claim 27 wherein said first and second layers are formed of an aluminum magnesium alloy and tantalum respectively.

Claim 35

Apparatus for the in situ generation of electrical current as recited in claim 27 wherein said insulating layer is inert in the biological environment.

Claim 36

Apparatus for the in situ generation of electrical current as recited in claim 31 wherein said insulating layer is a polymer.

Claim 37

Apparatus for the in situ generation of electrical current as recited in claim 25 wherein said first, second and third layers collectively form a planar apparatus.

Claim 38

Apparatus for the in situ generation of electrical current as recited in claim 25 wherein said first, second and third layers collectively form a substantially tubular wall structure.

Claim 39

Apparatus for the in situ generation of electrical current as recited in claim 34 wherein at least one of said first and second layers provides a self-supporting structure.