US5356632A
Expired / Lapsed
US
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Transdermal drug delivery device
Assignee: Elan Medical Technologies Ltd
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Filing: 1991-09-12
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Granted: 1994-10-18
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Expires: 2011-09-12
Abstract
Abstract A transdermal drug delivery device includes anode and cathode electrodes supported on a base member in spaced relation to each other to define a gap therebetween, a gel containing a liquid drug to be delivered covering the gap and in contact with both of the electrodes, and a liquid permeable sheet covering the gel containing the liquid to be delivered.
Inventors
- 👤 Joseph Gross
- 👤 Shlomo Zucker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 18:54
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0428; A61N1/0432; A61N1/044; A61N1/0448; A61N1/18; A61N1/20; A61N1/30; A61N1/303
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
85 words
A transdermal drug delivery device for application to a subject'skin, comprising: a base member of insulating material; an anode electrode and a cathode electrode supported on said base member in spaced relation to each other to define a gap therebetween; means for connecting said electrodes to a voltage source; and an insulating layer releasably containing a liquid drug to be delivered covering said gap and both of said electrodes such that neither of said electrodes comes into contact with the subject's skin when applied thereto.
Claim 2
Dependent Claim
85 words
A transdermal drug delivery device for application to a subject'skin, comprising: a base member of insulating material; an anode electrode and a cathode electrode supported on said base member in spaced relation to each other to define a gap therebetween; means for connecting said electrodes to a voltage source; and an insulating layer releasably containing a liquid drug to be delivered covering said gap and both of said electrodes such that neither of said electrodes comes into contact with the subject's skin when applied thereto.
Claim 3
Dependent Claim
23 words
The device according to claim 1, further including a liquid permeable sheet covering said insulating layer releasably containing the liquid to be delivered.
Claim 4
Dependent Claim
19 words
The device according to claim 2, wherein said liquid permeable sheet is a porous absorbent sheet of hydrophilic material.
Claim 5
Dependent Claim
38 words
The device according to claim 2, wherein said base member includes a backing sheet having an adhesive coating for adhesively applying the device to a patient's skin with the liquid permeable sheet in contact with the patient's skin.
Claim 6
Dependent Claim
31 words
The device according to claim 2, further including a wrist band for applying the device to the wrist of a patient, with the liquid-permeable sheet in contact with the patient's skin.
Claim 7
Dependent Claim
40 words
The device according to claim 1, wherein said base member further supports a battery having its positive-terminal connected to said anode electrode, and its negative-terminal connected to said cathode electrode for supplying current to said insulating layer via said electrodes.
Claim 8
Dependent Claim
25 words
The device according to claim 6, wherein said base member further supports an electrical control means for controlling the current supplied to said insulating layer.
Claim 9
Dependent Claim
42 words
The device according to claim 7, wherein said electrical control means comprises a presettable resistor for presetting the magnitude of the current to be supplied to said insulating layer, and an electrical switch for supplying the electrical current to said insulating layer.
Claim 10
Dependent Claim
46 words
The device according to claim 7, wherein said electrical control means comprises a preprogrammable microprocessor for pre-programming the magnitude of the current to be supplied to said insulating layer, and the time periods during which the electrical current is to be supplied to the insulating layer.
Claim 11
Dependent Claim
67 words
The device according to claim 1, wherein each of said electrodes includes a plurality of branches electrically connected together but physically spaced from each other, the branches of the anode electrode being paired with, but spaced from, the branches of the cathode electrode to form a plurality of gaps, all of which gaps are covered by said insulating layer releasably containing the liquid drug to be delivered.
Claim 12
Dependent Claim
33 words
The device according to claim 10, wherein said electrode branches are in the form of parallel strips, the strips of the anode electrode branches alternating with the strips of the cathode electrode branches.
Claim 13
Dependent Claim
51 words
The device according to claim 11, wherein said electrodes are arranged in a plurality of groups occupying different areas of said base sheet, enabling the electrodes of each group to be selectively energized at different times to deliver the drug of the insulating layer in the respective area at different times.
Claim 14
Dependent Claim
106 words
A transdermal drug delivery device for application to a subject's skin, comprising: a base member of insulating material; an anode electrode and a cathode electrode supported on said base member in spaced relation to each other to define a gap therebetween; an insulating layer including a gel containing a liquid drug to be delivered covering said gap and in contact with and covering both of said electrodes; means for connecting said electrodes to a voltage source; and a liquid permeable sheet covering said gel containing the liquid to be delivered such that neither of said electrodes comes into contact with the subject's skin when applied thereto.
Claim 15
Dependent Claim
106 words
A transdermal drug delivery device for application to a subject's skin, comprising: a base member of insulating material; an anode electrode and a cathode electrode supported on said base member in spaced relation to each other to define a gap therebetween; an insulating layer including a gel containing a liquid drug to be delivered covering said gap and in contact with and covering both of said electrodes; means for connecting said electrodes to a voltage source; and a liquid permeable sheet covering said gel containing the liquid to be delivered such that neither of said electrodes comes into contact with the subject's skin when applied thereto.
Claim 16
Dependent Claim
19 words
The device according to claim 13, wherein said liquid permeable sheet is a porous absorbent sheet of hydrophilic material.
Claim 17
Dependent Claim
41 words
The device according to claim 13, wherein said base member further supports a battery having its positive-terminal connected to said anode electrode, and its negative-terminal connected to said cathode electrode for supplying current to said gel in contact with said electrodes.
Claim 18
Dependent Claim
24 words
The device according to claim 13, wherein said base member further supports an electrical control mean for controlling the current supplied to said gel.
Claim 19
Dependent Claim
44 words
The device according to claim 16, wherein said electrical control means comprises a preprogrammable microprocessor for pre-programming the magnitude of the current to be supplied to said gel, and the time periods during which the electrical current is to be supplied to the gel.
Claim 20
Dependent Claim
65 words
The device according to claim 13, wherein each of said electrodes includes a plurality of branches electrically connected together but physically spaced from each other, the branches of the anode electrode being paired with, but spaced from, the branches of the cathode electrode to form a plurality of gaps, all of which gaps are covered by said gel containing the liquid drug to be delivered.
Claim 21
Dependent Claim
33 words
The device according to claim 18, wherein said electrode branches are in the form of parallel strips, the strips of the anode electrode branches alternating with the strips of the cathode electrode branches.
Claim 22
Dependent Claim
50 words
The device according to claim 19, wherein said electrodes are arranged in a plurality of groups occupying different areas of said base sheet, enabling the electrodes of each group to be selectively energized at different times to deliver the drug of the gel in the respective area at different times.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-10-17 | 1998-04-18 | 1998-10-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-10-17 | 2002-04-18 | 2002-10-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-10-17 | 2006-04-18 | 2006-10-18 | $7700.00 | Window Closed / Lapsed |