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US5356436A Expired / Lapsed US ⏱️ 0.0 years remaining

Materials for living hard tissue replacements

Assignee: TDK Corp
•
Filing: 1992-04-21
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Granted: 1994-10-18
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Expires: 2012-04-21
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Abstract

Abstract The materials for living hard tissue replacements of the present invention comprise a ceramic material which contain Cao and SiO 2 as essential components, and MgO as an optional components, are substantially free from calcium phosphate and are capable of forming a compound based on calcium phosphate by contact with an aqueous solution containing phosphorus, and show high biological affinity.

Inventors

  • 👤 Tohru Nonami
  • 👤 Hiroyasu Noma
  • 👤 Shinya Nakajima

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 09:20
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/02; A61L27/10; C; C04; C04B; C04B35/00; C04B35/01; C04B35/16; C04B35/22; Y; Y10; Y10S; Y10S623/00; Y10S623/901

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 110 words
A method for replacement of living hard tissue comprising: providing an implant comprising a ceramic material which contains at least 40% by volume of a diopside composition, a wollastonite composition or a mixture of diopside and wollastonite compositions, and which (i) contains CaO and SiO 2 as essential components, (ii) is substantially free from calcium phosphate and (iii) is capable of forming a compound based in calcium phosphate by contact with an aqueous solution containing phosphorous, said CaO and SiO 2 being present in a weight ratio of CaO to SiO 2 of between 1:4 and 6:1; and inserting said implant into a living body to replace living hard tissue.
Claim 2
Independent Claim 110 words
A method for replacement of living hard tissue comprising: providing an implant comprising a ceramic material which contains at least 40% by volume of a diopside composition, a wollastonite composition or a mixture of diopside and wollastonite compositions, and which (i) contains CaO and SiO 2 as essential components, (ii) is substantially free from calcium phosphate and (iii) is capable of forming a compound based in calcium phosphate by contact with an aqueous solution containing phosphorous, said CaO and SiO 2 being present in a weight ratio of CaO to SiO 2 of between 1:4 and 6:1; and inserting said implant into a living body to replace living hard tissue.
Claim 3
Dependent Claim 25 words
The process as claimed in claim 1, wherein said ceramic material contains MgO in addition to the essential components of CaO and SiO 2 .
Claim 4
Dependent Claim 35 words
The process as claimed in claim 2, wherein said ceramic material contains 10 to 88% by weight of CaO, 10 to 80% by weight of SiO 2 and 2 to 35% by weight of MgO.
Claim 5
Dependent Claim 35 words
The process as claimed in claim 3, wherein said ceramic material contains 18 to 47% by weight of CaO, 37 to 68% by weight of SiO 2 and 10 to 25% by weight of MgO.
Claim 6
Dependent Claim 21 words
The process as claimed in claim 1, wherein said ceramic material contains at least 40% by volume of a diopside composition.
Claim 7
Dependent Claim 32 words
The process as claimed in claim 1, wherein said ceramic material contains at least 50% by volume of a diopside composition, a wollastonite composition or a mixture of diopside and wollastonite compositions.
Claim 8
Dependent Claim 32 words
The process as claimed in claim 6, wherein said ceramic material contains 70% to 100% by volume of a diopside composition, a wollastonite composition or a mixture of diopside and wollastonite compositions.
Claim 9
Dependent Claim 25 words
The process as claimed in claim 1, wherein said implant comprises a substrate having a coat layer of said ceramic material on a surface thereof.
Claim 10
Dependent Claim 19 words
The process as claimed in claim 8, wherein said coat layer has a thickness of 1 to 5000 gm.
Claim 11
Dependent Claim 19 words
The process as claimed in claim 1, wherein said coat layer has a thickness of 10 to 2000 μm.
Claim 12
Dependent Claim 19 words
The process as claimed in claim 10, wherein said coat layer has a thickness of 20 to 1000 μm.
Claim 13
Dependent Claim 20 words
The process as claimed in claim 8, wherein said coat layer has a surface roughness of 1 to 200 μm.
Claim 14
Dependent Claim 20 words
The process as claimed in claim 12, wherein said coat layer has a surface roughness of 5 to 100 μm.
Claim 15
Dependent Claim 13 words
The process as claimed in claim 8, wherein said coat layer is porous.
Claim 16
Dependent Claim 16 words
The process as claimed in claim 8, wherein said substrate comprises metal, ceramic, glass or plastic.
Claim 17
Dependent Claim 48 words
The process as claimed in claim 6, wherein said substrate comprises a metal selected from the group consisting of Ti, W, Ni-Cr alloy, Fe-Cr-Al alloy, Ti-Zr alloy, Fe-Ni-Cr alloy, Mo, Ti-Al-V alloy, Co-Cr-Mo alloy, Ti-Mo alloy, Co-Cr-Ni alloy, stainless steel 304, stainless steel 310 and stainless steel 316.
Claim 18
Dependent Claim 16 words
The process as claimed in claim 6, wherein said substrate comprises Ti or an alloy thereof.
Claim 19
Dependent Claim 28 words
The process as claimed in claim 6, wherein said substrate comprises a ceramic selected from the group consisting of alumina, zirconia, silicon carbide, tungsten nitride and silicon nitride.
Claim 20
Dependent Claim 34 words
The process as claimed in claim 1, wherein said implant is a porous body of said ceramic material having a pore diameter of 5 to 2000 μm and a porosity of 10 to 80%.
Claim 21
Dependent Claim 20 words
The process as claimed in claim 19, wherein said porous body has a pore diameter of 10 to 1000 μm.
Claim 22
Dependent Claim 18 words
The process as claimed in claim 19, wherein said porous body has a porosity of 20 to 70%.
Claim 23
Dependent Claim 18 words
The process as claimed in claim 21, wherein said porous body has a porosity of 25 to 60%.

References Cited (Backward Citations)

US3926647A Cited
US4146936A Cited
GB2080281A Cited
US4352890A Cited
JPS61205637A Cited
US4871384A Cited
EP0389713A1 Cited
US5125971A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-10-17 1998-04-18 1998-10-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-10-17 2002-04-18 2002-10-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-10-17 2006-04-18 2006-10-18 $7700.00 Window Closed / Lapsed

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