US5340991A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fluorokinetic analysis of diffusion from a vessel
Assignee: University of Oklahoma
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Filing: 1993-05-21
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Granted: 1994-08-23
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Expires: 2013-05-21
Abstract
Abstract The present invention comprises an in vitro system called the Agarose Gel Vessel and a method of using fluorokinetic analysis for quantifying the diffusion of a fluorescent material through the agarose gel vessel and thereby characterizing the permeability of the vessel. The results obtained from the gel can be used to verify and develop protocols for investigating and treating angiopathies of the eye related to blood vessel permeability.
Inventors
- 👤 Stephen R. Fransen
- 👤 P. Lloyd Hilderbrand
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 17:11
CPC Classifications
G; G01; G01N; G01N15/00; G01N15/08; A; A61; A61B; A61B3/00; A61B3/0016; A61B3/0025; A61B3/10; A61B3/12; A61B3/1241; G01N21/00; G01N21/62; G01N21/63; G01N21/64
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
66 words
A method of characterizing the diffusion of a fluorescent material from a vessel, comprising: providing an agarose gel vessel; perfusing the agarose gel vessel with a solution containing a fluorescent material; digitally recording a fluorescent image of the agarose gel vessel at predetermined times for obtaining quantitative data; fitting a curve to the data; and using the curve to characterize the diffusion of the fluorescent material.
Claim 2
Independent Claim
66 words
A method of characterizing the diffusion of a fluorescent material from a vessel, comprising: providing an agarose gel vessel; perfusing the agarose gel vessel with a solution containing a fluorescent material; digitally recording a fluorescent image of the agarose gel vessel at predetermined times for obtaining quantitative data; fitting a curve to the data; and using the curve to characterize the diffusion of the fluorescent material.
References Cited (Backward Citations)
US5037207A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-08-22 | 1998-02-21 | 1998-08-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-08-22 | 2002-02-21 | 2002-08-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-08-22 | 2006-02-21 | 2006-08-23 | $7700.00 | Window Closed / Lapsed |