US5338772A
Expired / Lapsed
US
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Implant material
Assignee: Merck Patent GmbH
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Filing: 1992-06-22
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Granted: 1994-08-16
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Expires: 2012-06-22
Abstract
Abstract The invention relates to an implant material which is based on a composite material of calcium phosphate ceramic particles and bioabsorbable polymer, in which the proportion of calcium phosphate ceramic particles is at least 50% by weight and the particles are joined to one another by polymer bridges to give a three-dimensional open-pore structure in which the particle surfaces are covered with polymer to the extent of not more than 50%. This implant material is distinguished by particularly favorable growing-in and healing-in properties.
Inventors
- 👤 Hans-Jorg Bauer
- 👤 Gerd Bauer
- 👤 Elvira Dingeldein
- 👤 Helmut Wahlig
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 21:49
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/40; A61L27/44; A61L27/46; A61L27/50; A61L27/56; A61F; A61F2/00; A61F2/0077; Y; Y10; Y10T; Y10T428/00; Y10T428/249921; Y10T428/249953; Y10T428/25; Y10T428/258
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
66 words
An implant material comprising a composite material containing calcium phosphate ceramic particles and bioabsorbable polymer, wherein the proportion of calcium phosphate ceramic particles in the material is at least 50% by weight and said particles are joined to one another by polymer bridges, thereby defining a three-dimensional open-pore structure in which the particle surfaces are covered with polymer to the extent of not more than 50%.
Claim 2
Dependent Claim
66 words
An implant material comprising a composite material containing calcium phosphate ceramic particles and bioabsorbable polymer, wherein the proportion of calcium phosphate ceramic particles in the material is at least 50% by weight and said particles are joined to one another by polymer bridges, thereby defining a three-dimensional open-pore structure in which the particle surfaces are covered with polymer to the extent of not more than 50%.
Claim 3
Dependent Claim
27 words
An implant material according to claim 1, wherein said composite material contains at least 50 wt. % and not more than 98 wt. % of said particles.
Claim 4
Dependent Claim
25 words
An implant material according to claim 2, wherein said ceramic particles are made of sintered bone and said polymer is based on polylactides and/or polyglycolides.
Claim 5
Dependent Claim
14 words
An implant material according to claim 3, wherein said bone ceramic particles are porous.
Claim 6
Dependent Claim
17 words
An implant material according to claim 4, wherein the porous bone ceramic particles have an open porosity.
Claim 7
Dependent Claim
20 words
An implant material according to claim 5, wherein said composite contains sintered spongiosa granules as said porous bone ceramic particles.
Claim 8
Dependent Claim
19 words
An implant material according to claim 6, wherein said composite contains not more than 80% by weight of particles.
Claim 9
Dependent Claim
16 words
An implant material according to claim 3, wherein said bone ceramic particles have a low porosity.
Claim 10
Dependent Claim
19 words
An implant material according to claim 8, wherein said composite contains sintered corticalis granules as said bone ceramic particles.
Claim 11
Dependent Claim
19 words
An implant material according to claim 9, wherein said composite contains not more than 90% by weight of particles.
Claim 12
Dependent Claim
18 words
An implant material according to claim 2, wherein said composite further contains one or more pharmaceutically active compounds.
Claim 13
Dependent Claim
31 words
An implant material according to claim 2, wherein said composite is a composite material obtained by heating a mixture of said ceramic particles and bioabsorbable polymer by means of microwave radiation.
Claim 14
Dependent Claim
18 words
An implant material according to claim 2, wherein said particles have a particle size of 20 μm-5 mm.
Claim 15
Dependent Claim
17 words
An implant material according to claim 2, wherein said polymer has an average molecular weight of 200-10,000.
Claim 16
Dependent Claim
17 words
An implant material according to claim 2, wherein the pore size of said composite is 0.01-1 mm.
Claim 17
Dependent Claim
17 words
An implant material according to claim 2, wherein said composite contains 75-95% by weight of said particles.
Claim 18
Dependent Claim
88 words
A process for the preparation of an implant material based on a composite material of calcium phosphate ceramic particles and bioabsorbable polymer wherein the particles are joined to one another by polymer bridges to give a three-dimensionally open-pore structure in which the particle surfaces are covered with polymer to the extent of not more than 50%, said process comprising heating by means of microwave radiation a mixture of said ceramic particles and bioabsorbable polymer, wherein the proportion of calcium phosphate ceramic particles is at least 50% by weight.
Claim 19
Dependent Claim
88 words
A process for the preparation of an implant material based on a composite material of calcium phosphate ceramic particles and bioabsorbable polymer wherein the particles are joined to one another by polymer bridges to give a three-dimensionally open-pore structure in which the particle surfaces are covered with polymer to the extent of not more than 50%, said process comprising heating by means of microwave radiation a mixture of said ceramic particles and bioabsorbable polymer, wherein the proportion of calcium phosphate ceramic particles is at least 50% by weight.
Claim 20
Dependent Claim
24 words
A process according to claim 17, wherein said ceramic particles are sintered bone ceramic particles and said polymer is based on polylactides and/or polyglycolides.
Claim 21
Dependent Claim
35 words
In a process for shaping an implant material, the improvement wherein an implant material according to claim 2 is heated to plastic deformability by means of microwave radiation and is then deformed by mechanical pressure.
References Cited (Backward Citations)
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