US5330507A
Expired / Lapsed
US
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Implantable electrical vagal stimulation for prevention or interruption of life threatening arrhythmias
Assignee: Medtronic Inc
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Filing: 1992-04-24
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Granted: 1994-07-19
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Expires: 2012-04-24
Abstract
Abstract A method and apparatus for stimulating the right or left vagus nerve with continuous and/or phasic electrical pulses, the latter in a specific relationship with the R-wave of the patient's electrogram. The automatic detection of the need for vagal stimulation is responsive to increases in the heart rate greater than a predetermined threshold, the occurrence of frequent or complex ventricular arrhythmias, and/or a change in the ST segment elevation greater than a predetermined or programmed threshold. The system is described with a microprocessor driven, brady therapy device with programming and telemetry capabilities for recording in memory the aforementioned stimulation triggering indicia, including electrogram segments for periods of time preceding and following each instance of vagal stimulation for telemetry out on command.
Inventors
- 👤 Peter J. Schwartz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 16:10
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/3605; A61N1/3606; A61N1/36114; A61N1/362; A61N1/3621; A61N1/365; A61N1/36585
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
150 words
A method for treating a cardiac arrhythmia comprising the steps of: continuously measuring the electrogram of the patient's heart; detecting certain characteristics of said electrogram indicative of tachycardia; initiating the storage of a sequence of said characteristics of said electrogram upon detection of a tachycardia; delivering one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; providing a patient selection trigger to permit a patient to cause the delivery of a preset electrical stimulation therapy to the patient's nervous system; providing patient initiated storage means to permit the patient to initiate storage of said sequence of said characteristics of said electrogram and said delivering of said one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; and initiating the storage of a further sequence of said characteristics of said electrogram following delivery of said stimulation therapies.
Claim 2
Independent Claim
150 words
A method for treating a cardiac arrhythmia comprising the steps of: continuously measuring the electrogram of the patient's heart; detecting certain characteristics of said electrogram indicative of tachycardia; initiating the storage of a sequence of said characteristics of said electrogram upon detection of a tachycardia; delivering one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; providing a patient selection trigger to permit a patient to cause the delivery of a preset electrical stimulation therapy to the patient's nervous system; providing patient initiated storage means to permit the patient to initiate storage of said sequence of said characteristics of said electrogram and said delivering of said one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; and initiating the storage of a further sequence of said characteristics of said electrogram following delivery of said stimulation therapies.
Claim 3
Dependent Claim
79 words
The method of claim 1 further comprising the steps of: examining the QRST segment of the patient's electrogram; measuring the ST segment elevation of said QRST components of said electrogram; comparing the measured ST segment elevations to a threshold ST segment elevation and counting the number of elevated ST segments exceeding the threshold ST segment elevation; and delivering said stimulation therapies if a pre-selected number of elevated ST segments among a total number of measured ST segments are found.
Claim 4
Independent Claim
63 words
The method of claims 1 or 2 further comprising the steps of: detecting successive R-waves of the patient's electrogram; measuring successive R--R intervals of the patient's electrogram and comparing the measured R--R intervals against a tachycardia interval threshold; and delivering said stimulation therapies if a predetermined number of R--R intervals within a run of successive R-waves are less than said tachycardia threshold interval.
Claim 5
Dependent Claim
54 words
The method of claim 1 wherein said step of storing the electrogram after delivery of stimulation further comprises the steps of: confirming that the delivered stimulation therapy successively converted the tachycardia to a heart rate below the tachycardia threshold; and storing a predetermined number of successive R--R intervals following delivery of a successful therapy.
Claim 6
Dependent Claim
147 words
Apparatus for treating a cardiac arrhythmia comprising: means for continuously measuring the electrogram of the patient's heart; means for detecting certain characteristics of said electrogram indicative of tachycardia; means for a sequence of said characteristics of said electrogram upon detection of tachycardia; means for delivering one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; patient selection trigger means for permitting a patient to cause the delivery of a preset electrical stimulation therapy to the patient's nervous system; patient initiated storage means for permitting the patient to initiate storage of said sequence of said characteristics of said electrogram and said delivering of said one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; and means for storing of a further sequence of said characteristics of said electrogram following delivery of said stimulation therapies.
Claim 7
Dependent Claim
147 words
Apparatus for treating a cardiac arrhythmia comprising: means for continuously measuring the electrogram of the patient's heart; means for detecting certain characteristics of said electrogram indicative of tachycardia; means for a sequence of said characteristics of said electrogram upon detection of tachycardia; means for delivering one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; patient selection trigger means for permitting a patient to cause the delivery of a preset electrical stimulation therapy to the patient's nervous system; patient initiated storage means for permitting the patient to initiate storage of said sequence of said characteristics of said electrogram and said delivering of said one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; and means for storing of a further sequence of said characteristics of said electrogram following delivery of said stimulation therapies.
Claim 8
Dependent Claim
86 words
The apparatus of claim 5 further comprising: means for examining the QRST segment of the patient's electrogram; means for measuring the ST segment elevation of said QRST components of said electrogram; means for comparing the measured ST segment elevations to a threshold ST segment elevation and means for counting the number of elevated ST segments exceeding the threshold ST segment elevation; and means for delivering said stimulation therapies if a preselected number of elevated ST segments among a total number of measured ST segments are found.
Claim 9
Independent Claim
66 words
The apparatus of claims 5 or 6 further comprising: means for detecting successive R-waves of the patient's electrogram; means for measuring successive R--R intervals of the patient's electrogram and comparing the measured R--R intervals against a tachycardia interval threshold; and means for delivering said stimulation therapies if a predetermined number of R--R intervals within a run of successive R-waves are less than said tachycardia threshold interval.
Claim 10
Dependent Claim
55 words
The apparatus of claim 5 wherein said step of storing the electrogram after delivery of stimulation further comprises: means for confirming that the delivered stimulation therapy successively converted the tachycardia to a heart rate below the tachycardia threshold; and means for storing a predetermined number of successive R--R intervals following delivery of a successful therapy.
Claim 11
Independent Claim
152 words
A method for treating a cardiac arrhythmia comprising the steps of: continuously measuring the electrogram of the patient's heart; examining the QRST segment of the patient's electrogram; measuring the ST segment elevation of said QRST components of said electrogram; comparing the measured ST segment elevation to a threshold ST segment elevation and counting the number of elevated ST segments exceeding the threshold ST segment elevation; and delivering one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; providing a patient selection trigger to permit a patient to cause the delivery of a preset electrical stimulation therapy to the patient's nervous system; and providing patient initiated storage means to permit the patient to initiate storage of said sequence of said characteristics of said electrogram and said delivering of said one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate.
Claim 12
Independent Claim
152 words
A method for treating a cardiac arrhythmia comprising the steps of: continuously measuring the electrogram of the patient's heart; examining the QRST segment of the patient's electrogram; measuring the ST segment elevation of said QRST components of said electrogram; comparing the measured ST segment elevation to a threshold ST segment elevation and counting the number of elevated ST segments exceeding the threshold ST segment elevation; and delivering one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate; providing a patient selection trigger to permit a patient to cause the delivery of a preset electrical stimulation therapy to the patient's nervous system; and providing patient initiated storage means to permit the patient to initiate storage of said sequence of said characteristics of said electrogram and said delivering of said one or more electrical stimulation therapies to the patient's nervous system for depressing the patient's heart rate.
Claim 13
Dependent Claim
61 words
The method of claim 9 further comprising the steps of: detecting successive R-waves of the patient's electrogram; measuring successive R--R intervals of the patient's electrogram and comparing the measured R--R intervals against a tachycardia interval threshold; and delivering said stimulation therapies if a predetermined number of R--R intervals within a run of successive R-waves are less than said tachycardia threshold interval.
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