Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
258 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period of time comprising: a drug reservoir for containing at least one drug and having means for attachment to the skin of a patient and making an electrical connection therewith at an interface between the reservoir and the skin of the patient, means connected to said reservoir including a source of variable electrical potential for effecting delivery of said drug transdermally into the blood of the patient when the applicator is in use, said source having one electrical terminal electrically connected to said reservoir spaced from said interface and a second terminal positionable on the surface of the skin of the patient spaced from said interface and in circuit with said interface when said applicator is in use, means in said source of variable electrical potential for cyclically generating a complex composite pulse signal applied to said one terminal, said reservoir and through said interface when said second terminal is in electrical contact with the skin of the patient, said complex composite pulse signal comprising a sequence of pulsed direct current pulses of different waveforms, amplitudes, frequencies and repetition rates, and timing means for applying the complex composite pulse signal as a composite total waveform formed by a plurality of signals with selected sequences of different time intervals of waveform components effective to develop and maintain current flow including current flow within blood capillaries of the patient in a desired same direction of current flow.
Claim 2
Dependent Claim
258 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period of time comprising: a drug reservoir for containing at least one drug and having means for attachment to the skin of a patient and making an electrical connection therewith at an interface between the reservoir and the skin of the patient, means connected to said reservoir including a source of variable electrical potential for effecting delivery of said drug transdermally into the blood of the patient when the applicator is in use, said source having one electrical terminal electrically connected to said reservoir spaced from said interface and a second terminal positionable on the surface of the skin of the patient spaced from said interface and in circuit with said interface when said applicator is in use, means in said source of variable electrical potential for cyclically generating a complex composite pulse signal applied to said one terminal, said reservoir and through said interface when said second terminal is in electrical contact with the skin of the patient, said complex composite pulse signal comprising a sequence of pulsed direct current pulses of different waveforms, amplitudes, frequencies and repetition rates, and timing means for applying the complex composite pulse signal as a composite total waveform formed by a plurality of signals with selected sequences of different time intervals of waveform components effective to develop and maintain current flow including current flow within blood capillaries of the patient in a desired same direction of current flow.
Claim 3
Dependent Claim
31 words
The transdermal applicator according to claim 1, in which said timing means comprises spectral timing means comprising a timer and a microprocessor for selectively varying the time intervals of said sequences.
Claim 4
Dependent Claim
24 words
The transdermal applicator according to claim 1, in which said source of variable electrical potential comprises means for alternating the polarity of the source.
Claim 5
Dependent Claim
21 words
The transdermal applicator according to claim 1, including means for creating a short-circuit between said one terminal and said second terminal.
Claim 6
Dependent Claim
21 words
The transdermal applicator according to claim 1, including means for selectively interrupting pulse components of said complex signal in said sequences.
Claim 7
Dependent Claim
23 words
A transdermal applicator as claimed in claim 1, wherein a first signal is a DC pulse modulated at said 2500 Hz± 1000 hz.
Claim 8
Dependent Claim
14 words
A transdermal applicator as claimed in claim 1, and further including an AC pulse.
Claim 9
Dependent Claim
22 words
A transdermal applicator as claimed in claim 7, wherein said AC pulse includes a cycle having a period of 0.4 ms±0.2 ms.
Claim 10
Dependent Claim
21 words
A transdermal applicator as claimed in claim 8, wherein the repetition rate of said AC pulse is at least 60 Hz.
Claim 11
Dependent Claim
16 words
A transdermal applicator as claimed in claim 7, wherein said AC pulse is a rectangular wave.
Claim 12
Dependent Claim
15 words
A transdermal applicator as claimed in claim 1, and further including a modulated DC signal.
Claim 13
Dependent Claim
34 words
A transdermal applicator as claimed in claim 11, wherein said modulator signal has a duration of between about 2 ms to about 6 and frequency range between about 570 Hz and about 870 Hz.