US5290699A
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Double mutants of bacteriorhodopsin
Assignee: MIB Munich Innovative Biomaterials GmbH
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Filing: 1991-11-14
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Granted: 1994-03-01
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Expires: 2011-11-14
Abstract
Abstract Double mutants of bacteriorhodopsin are mutated in the amino acid positions 85 and 96 and are expressed in Halobacteria. The mutants have an altered absorption maximum of their ground state and of their intermediate with the longest life. These mutants pump anions in place of protons.
Inventors
- 👤 Dieter Oesterhelt
- 👤 Susanne Meessen
- 👤 Jorg Tittor
- 👤 Anja Matuszak
- 👤 Klaus May
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 20:04
CPC Classifications
C; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C07; C07K; C07K14/00; C07K14/195; C07K14/215; C12R; C12R2001/00; C12R2001/01
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
27 words
A bacteriorhodopsin protein comprising: bacteriorhodopsin having aspartic acid mutated to asparagine in amino acid positions 85 and 96 of the opsin of a wild-type strain of Halobacteria.
Claim 2
Dependent Claim
27 words
A bacteriorhodopsin protein comprising: bacteriorhodopsin having aspartic acid mutated to asparagine in amino acid positions 85 and 96 of the opsin of a wild-type strain of Halobacteria.
Claim 3
Dependent Claim
21 words
The protein as claimed in claim 1 wherein the gene encoding said opsin originates from the wild-type strain of Halobacterium, halobium.
Claim 4
Dependent Claim
12 words
A strain of Halobacteria which produces the bacteriorhodopsin according to claim 1.
Claim 5
Dependent Claim
16 words
A cell membrane fragment containing said protein from the strain of Halobacteria according to claim 3.
Claim 6
Dependent Claim
7 words
The H. halobium strain HN5 (DSM 6229).
Claim 7
Dependent Claim
7 words
The H. halobium strain HN5 (DSM 6229).
Claim 8
Dependent Claim
12 words
A strain of Halobacteria which produces the bacteriorhodopsin according to claim 1.
Claim 9
Dependent Claim
16 words
A cell membrane fragment containing said protein from a strain of Halobacteria according to claim 6.
Claim 10
Dependent Claim
5 words
The vector p319/D85,96N (DSM 6225).
Claim 11
Dependent Claim
5 words
The vector p319/D85,96N (DSM 6225).
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-02-28 | 1997-08-30 | 1998-03-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-02-28 | 2001-08-30 | 2002-03-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-02-28 | 2005-08-30 | 2006-03-01 | $7700.00 | Window Closed / Lapsed |