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US5284568A Expired / Lapsed US ⏱️ 0.0 years remaining

Disposable cartridge for ion selective electrode sensors

Assignee: Siemens Healthcare Diagnostics Inc
•
Filing: 1992-07-17
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Granted: 1994-02-08
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Expires: 2012-07-17
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Abstract

Abstract A readily disposable ion selective electrode assembly, free of onboard reagents, for use in analyzers has a reference element and plural sensor elements linearly positioned in parallel on a substrate. An elastomeric flow channel member containing two parallel grooves creates flow channels on the substrate above the elements. The substrate holds the elastomer in compression and is retained by snaps injection molded into a housing. Electrical contacts and leakfree fluidic connections are provided by spring loaded connectors through the housing. Reference and sample fluids are drawn through the respective flow channels and come together to form a liquid junction downstream from the sensor elements. Bubbles, that might otherwise cause erroneous results, are detected.

Inventors

  • 👤 Salvatore J. Pace
  • 👤 James D. Hamerslag

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 04:30
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/403

Claims Analysis

Total Claims: 19
Claim 1
Independent Claim 185 words
A disposable sensor assembly for use in an analyzer, said assembly comprising: a substrate having a face with a reference element and plural sensor elements formed thereon, an electrical contact positioned on the substrate face for each element, a flow channel member having first and second opposed faces, the first face defining a pair of grooves positioned respectively over the substrate reference and sensor elements and joined together at one end of each groove, thereby defining liquid flow channels, the flow channel member defining orifices interconnecting the opposed faces at the one groove end and at each other groove end, and a housing having a wall and means for holding the substrate relative to the wall to compress the flow channel member therebetween, whereby the liquid flow channels are leak-free, the wall defining ports for providing access to the flow channel member orifices and the substrate electrical contacts, said analyzer having a receptacle to removably receive the assembly, electrical connectors to operatively engage the substrate electrical contacts, and liquid connectors adapted to operatively engage and apply liquids to and from the flow channel member orifices.
Claim 2
Dependent Claim 185 words
A disposable sensor assembly for use in an analyzer, said assembly comprising: a substrate having a face with a reference element and plural sensor elements formed thereon, an electrical contact positioned on the substrate face for each element, a flow channel member having first and second opposed faces, the first face defining a pair of grooves positioned respectively over the substrate reference and sensor elements and joined together at one end of each groove, thereby defining liquid flow channels, the flow channel member defining orifices interconnecting the opposed faces at the one groove end and at each other groove end, and a housing having a wall and means for holding the substrate relative to the wall to compress the flow channel member therebetween, whereby the liquid flow channels are leak-free, the wall defining ports for providing access to the flow channel member orifices and the substrate electrical contacts, said analyzer having a receptacle to removably receive the assembly, electrical connectors to operatively engage the substrate electrical contacts, and liquid connectors adapted to operatively engage and apply liquids to and from the flow channel member orifices.
Claim 3
Dependent Claim 34 words
An assembly as set forth in claim 1 wherein the housing holding means includes side walls on the housing, the walls having snaps positioned to retain the substrate in a substantially leak free manner.
Claim 4
Dependent Claim 15 words
An assembly as set forth in claim 2 wherein the flow channel member is elastomeric.
Claim 5
Dependent Claim 30 words
An assembly as set forth in claim 3 wherein the flow channel member second face has ribs transversely disposed relative to the defined channels for maintaining integrity of the channels.
Claim 6
Dependent Claim 39 words
An assembly as set forth in claim 4 wherein the flow channel member second face defines a cavity, and the housing wall has ribs positioned to engage the cavity, thereby to position the flow channel member in the housing.
Claim 7
Dependent Claim 42 words
An assembly as set forth in claim 2 wherein the flow channel member second face defines a cavity, and the housing wall has ribs positioned to engage the flow channel member cavity, thereby to position the flow channel member in the housing.
Claim 8
Dependent Claim 42 words
An assembly as set forth in claim 1 wherein the flow channel member second face defines a cavity, and the housing wall has ribs positioned to engage the flow channel member cavity, thereby to position the flow channel member in the housing.
Claim 9
Dependent Claim 40 words
An assembly as set forth in claim 5 wherein the substrate face has a ground element positioned at the junction of the channels in the flow channel member and an electrical contact therefore positioned away from the flow channel member.
Claim 10
Dependent Claim 42 words
An assembly as set forth in claim 4 wherein the substrate face has a ground element positioned to be at the junction of the channels in the flow channel member and an electrical contact therefore positioned away from the flow channel member.
Claim 11
Dependent Claim 29 words
An assembly as set forth in claim 8 wherein the substrate face has a bubble sensing element positioned to be in one of the flow channel member defined channels.
Claim 12
Dependent Claim 26 words
An assembly as set forth in claim 10 wherein analyzer includes electronic circuitry connected to the pins for measuring electrical signals provided by the sensing elements.
Claim 13
Dependent Claim 15 words
An assembly as set forth in claim 1 wherein the flow channel member is elastomeric.
Claim 14
Dependent Claim 25 words
An assembly as set forth in claim 12 wherein the analyzer includes means for introducing liquid to be analyzed to one of the fluid connectors.
Claim 15
Dependent Claim 150 words
A disposable sensor assembly for use in an analyzer, said assembly comprising: a substrate having a face with a linearly disposed reference element and plural sensor elements formed thereon, an electrical contact positioned on the substrate face for each element, a flow channel member having first and second opposed faces, the first face defining a pair of grooves positioned respectively over the substrate reference and sensor elements and joined together at one end of each groove, thereby defining liquid flow channels, the flow channel member defining orifices interconnecting the opposed faces at the one groove end and at each other groove end, and a housing having a wall and means for holding the substrate relative to the wall to compress the flow channel member therebetween, whereby the flow channels are leak free, the wall defining ports for providing access to the flow channel member orifices and the substrate electrical contacts.
Claim 16
Dependent Claim 150 words
A disposable sensor assembly for use in an analyzer, said assembly comprising: a substrate having a face with a linearly disposed reference element and plural sensor elements formed thereon, an electrical contact positioned on the substrate face for each element, a flow channel member having first and second opposed faces, the first face defining a pair of grooves positioned respectively over the substrate reference and sensor elements and joined together at one end of each groove, thereby defining liquid flow channels, the flow channel member defining orifices interconnecting the opposed faces at the one groove end and at each other groove end, and a housing having a wall and means for holding the substrate relative to the wall to compress the flow channel member therebetween, whereby the flow channels are leak free, the wall defining ports for providing access to the flow channel member orifices and the substrate electrical contacts.
Claim 17
Dependent Claim 28 words
An assembly as set forth in claim 14 wherein the housing holding means includes side walls on the housing, the walls having snaps positioned to retain the substrate.
Claim 18
Dependent Claim 30 words
An assembly as set forth in claim 14 wherein the flow channel member second face has ribs transversely disposed relative to the defined channels for maintaining integrity of the channels.
Claim 19
Dependent Claim 42 words
An assembly as set forth in claim 14 wherein the flow channel member second face defines a cavity, and the housing wall has ribs positioned to engage the flow channel member cavity, thereby to position the flow channel member in the housing.

References Cited (Backward Citations)

US4810251A Cited
US4786394A Cited
US4994167A Cited
US5004583A Cited
US4871439A Cited
US5018527A Cited
US4933048A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-02-07 1997-08-09 1998-02-08 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-02-07 2001-08-09 2002-02-08 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-02-07 2005-08-09 2006-02-08 $7700.00 Window Closed / Lapsed

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