Tonometry system for determining blood pressure

Claim 2

For use in a system for noninvasively determining the intra-arterial blood pressure of a patient, a tissue contact stress sensing apparatus comprising: a continuous diaphragm, means for placing said continuous diaphragm against a patient's tissue which covers an underlying artery, said diaphragm adapted to deform in response to stress in said tissue caused by the intra-arterial blood pressure of said artery, semiconductor means placed in close proximity to and spaced apart from said continuous diaphragm for irradiating said diaphragm with electromagnetic radiation, means for receiving said electromagnetic radiation reflected from said continuous diaphragm, whereby the quantity of electromagnetic radiation received by said receiving means is a function of the displacement of said continuous diaphragm in response to said tissue stress caused by said intra-arterial blood pressure of said artery.

Claim 3

The tissue contact stress sensing apparatus of claim 1 wherein said diaphragm is comprised of silicon.

Claim 4

The tissue contact stress sensing apparatus of claim 2, wherein said diaphragm is comprised of single crystal silicon.

Claim 5

The tissue contact stress sensing apparatus of claim 2, wherein said diaphragm is formed from a silicon wafer.

Claim 6

The tissue contact stress sensing apparatus of claim 4, wherein said diaphragm is formed from a longitudinal trough in said silicon wafer and said trough includes a cross-sectional profile generally resembling a tetragonal-pyramidal geometry.

Claim 7

The tissue contact stress sensing apparatus of claim 5, wherein said trough has a generally planar bottom.

Claim 8

The tissue contact stress sensing apparatus of claim 1, wherein said diaphragm is formed from a silicon wafer and wherein said wafer includes a longitudinal trough therein forming one side of said diaphragm, and wherein said trough has a bottom which is coated with a reflective material for reflecting the electromagnetic radiation irradiated by said irradiating means.

Claim 9

The tissue contact stress sensing apparatus of claim 7, wherein said trough bottom is generally 6.5×10 -6 meters thick.

Claim 10

The tissue contact stress sensing apparatus of claim 7, wherein said trough bottom is coated with metal.

Claim 11

The tissue contact stress sensing apparatus of claim 9, wherein said metal is selected from the group consisting of gold and aluminum.

Claim 12

The tissue contact stress sensing apparatus of claim 9, wherein said metal coating is generally 600 angstroms thick.

Claim 13

For use in a system for noninvasively determining the intra-arterial blood pressure of a patient, a tissue contact stress sensor for generating a tissue contact stress signal indicative of said intra-arterial blood pressure and a correction signal for compensating for errors in said tissue contact stress signal caused by temperature drift and aging of said sensor, said system comprising: a continuous diaphragm having a responsive portion and a non-responsive portion, means for placing said responsive portion against a patient's tissue which covers an underlying artery, said responsive portion adapted to deform in response to said intra-arterial blood pressure of said artery, semiconductor means, spaced apart from and placed in close proximity to said continuous diaphragm, for irradiating said continuous diaphragm with electromagnetic radiation, means for receiving said electromagnetic radiation reflected from said responsive portion and said non-responsive portion of said continuous diaphragm, means for converting said radiation received from said responsive portion of said continuous diaphragm into a tissue contact stress signal representing intra-arterial blood pressure data, means for converting said radiation received from said non-responsive portion of said continuous diaphragm into a correction signal which represents reference data which is indicative of at least one reference factor, and means for combining said correction signal with said tissue contact stress signal thereby minimizing the dependence of said blood pressure data on at least one of said reference factors.

Claim 14

For use in a system for noninvasively determining the intra-arterial blood pressure of a patient, a tissue contact stress sensor for generating a tissue contact stress signal indicative of said intra-arterial blood pressure and a correction signal for compensating for errors in said tissue contact stress signal caused by temperature drift and aging of said sensor, said system comprising: a continuous diaphragm having a responsive portion and a non-responsive portion, means for placing said responsive portion against a patient's tissue which covers an underlying artery, said responsive portion adapted to deform in response to said intra-arterial blood pressure of said artery, semiconductor means, spaced apart from and placed in close proximity to said continuous diaphragm, for irradiating said continuous diaphragm with electromagnetic radiation, means for receiving said electromagnetic radiation reflected from said responsive portion and said non-responsive portion of said continuous diaphragm, means for converting said radiation received from said responsive portion of said continuous diaphragm into a tissue contact stress signal representing intra-arterial blood pressure data, means for converting said radiation received from said non-responsive portion of said continuous diaphragm into a correction signal which represents reference data which is indicative of at least one reference factor, and means for combining said correction signal with said tissue contact stress signal thereby minimizing the dependence of said blood pressure data on at least one of said reference factors.

Claim 15

The tissue contact stress sensor of claim 12, wherein said reference factors include temperature and aging of said diaphragm.

Claim 16

The tissue contact stress sensor of claim 12, wherein said responsive and non-responsive portions of said continuous diaphragm are fabricated from substantially the same materials and at substantially the same time.

Claim 17

The tissue contact stress sensor of claim 12, wherein said continuous diaphragm is comprised of single crystal silicon.

Claim 18

The tissue contact stress sensor of claim 12, wherein said electromagnetic radiation is selected from the group consisting of visible, infrared, and ultraviolet light.

Claim 19

The tissue contact stress sensor of claim 12, wherein said continuous diaphragm is comprised of a silicon base having a longitudinal trough therein.

Claim 20

The tissue contact stress sensor of claim 17, wherein said trough has a generally planar bottom.

Claim 21

The tissue contact stress sensor of claim 18, wherein said trough bottom is generally 6.5×10 -6 meters thick.