US5283191A
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Mareks' disease virus vaccine
Assignee: Akzo NV
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Filing: 1992-07-10
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Granted: 1994-02-01
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Expires: 2012-07-10
Abstract
Abstract The invention is concerned with the MD18 and MD20 polypeptides of Marek's Disease virus which can be used to vaccinate poultry against MD. The invention also relates to nucleic acid sequences encoding the MD18 or MD20 polypeptides. Said sequences can be used for the preparation of a subunit or vector vaccine.
Inventors
- 👤 Robin W. Morgan
- 👤 Johannes A. J. Claessens
- 👤 Martha J. Willemse
- 👤 Paulus J. A. Sondermeijer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 08:40
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; A; A61; A61P; A61P31/00; A61P31/12; A61K; A61K39/00; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16311; C12N2710/16322
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
52 words
An isolated and purified nucleic acid molecule encoding a Marek's disease virus polypeptide selected from the group consisting of: a. MD18 having an amino acid sequence shown in SEQ ID NO:2, b. MD20 having an amino acid sequence shown in SEQ ID NO:4 and c. an antigenic fragment of MD18 on MD20.
Claim 2
Dependent Claim
52 words
An isolated and purified nucleic acid molecule encoding a Marek's disease virus polypeptide selected from the group consisting of: a. MD18 having an amino acid sequence shown in SEQ ID NO:2, b. MD20 having an amino acid sequence shown in SEQ ID NO:4 and c. an antigenic fragment of MD18 on MD20.
Claim 3
Dependent Claim
39 words
An isolated and purified nucleic acid molecule which comprises a DNA sequence selected from the group consisting of SEQ ID:1, SEQ ID NO:3, and a DNA sequence encoding an antigenic fragment of SEQ ID NO:1 or SEQ ID NO:3.
Claim 4
Dependent Claim
39 words
An isolated and purified nucleic acid molecule which comprises a DNA sequence selected from the group consisting of SEQ ID:1, SEQ ID NO:3, and a DNA sequence encoding an antigenic fragment of SEQ ID NO:1 or SEQ ID NO:3.
Claim 5
Dependent Claim
22 words
A recombinant nucleic acid molecule according to claim 1, wherein the nucleic acid molecule is operably linked to an expression control sequence.
Claim 6
Dependent Claim
21 words
A recombinant nucleic acid molecule according to claim 2, wherein the DNA sequence is operably linked to an expression control sequence.
Claim 7
Dependent Claim
13 words
A host cell transformed with a nucleic acid molecule according to claim 1.
Claim 8
Dependent Claim
13 words
A host cell transformed with a nucleic acid sequence according to claim 2.
Claim 9
Dependent Claim
11 words
A viral vector comprising the nucleic acid molecule of claim 3.
Claim 10
Dependent Claim
10 words
A host cell transfected with the vector of claim 7.
Claim 11
Dependent Claim
14 words
A host cell transformed with a recombinant nucleic acid molecule according to claim 3.
Claim 12
Dependent Claim
11 words
A viral vector comprising the nucleic acid molecule of claim 4.
Claim 13
Dependent Claim
10 words
A host cell transfected with the vector of claim 10.
Claim 14
Dependent Claim
11 words
A vector comprising a nucleic acid molecule according to claim 1.
Claim 15
Dependent Claim
11 words
The vector of claim 12, wherein said vector is a virus.
Claim 16
Dependent Claim
11 words
A host cell containing a viral vector according to claim 13.
Claim 17
Dependent Claim
11 words
A vector comprising a nucleic acid molecule according to claim 2.
Claim 18
Dependent Claim
11 words
The vector of claim 15, wherein said vector is a virus.
Claim 19
Dependent Claim
11 words
A host cell containing a viral vector according to claim 16.
References Cited (Backward Citations)
WO1990002803A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1997-01-31 | 1997-08-02 | 1998-02-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-01-31 | 2001-08-02 | 2002-02-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-01-31 | 2005-08-02 | 2006-02-01 | $7700.00 | Window Closed / Lapsed |