Dual chamber cardiac pacing from a single electrode

Claim 1

A pacemaker, comprising: a pulse generator, for producing cardiac stimulating pulses; a lead, coupled to said pulse generator via a first coupling capacitor, having an electrode on its distal end, said electrode being disposed in a venous channel of a patient's heart; signal processing circuitry means, coupled to said lead via a second coupling capacitor, for receiving from said lead electrical cardiac signals received by said electrode in said venous channel and said signal processing circuitry filtering and amplifying said cardiac signals to produce a processed cardiac output signal; a first sense amplifier, coupled to said signal processing circuitry and receiving said processed cardiac output signal, said first sense amplifier having a first sensitivity threshold voltage such that electrical signals having a voltage level below said first sensitivity threshold are not amplified by said first sense amplifier; a second sense amplifier, coupled to said signal processing circuitry and receiving said processed cardiac output signal, said second sense amplifier having a second sensitivity threshold voltage, higher than said first sensitivity threshold voltage, such that electrical signals having a voltage level below said second sensitivity threshold are not amplified by said second sense amplifier; logic circuitry, having first and second inputs for receiving first and second input signals, and having first and second outputs for producing first and second output signals, said first and second inputs coupled to said first and second sense amplifiers, respectively; such that a processed cardiac output signal which has a voltage which exceeds said first sensitivity threshold voltage but does not exceed said second sensitivity threshold voltage causes said first output signal, and not said second output signal, to be asserted, and such that a processed electrical cardiac signal which has a voltage which exceeds both said first and second sensitivity threshold voltages causes said second output signal and not said first output signal to be asserted; said pacemaker further comprising controlling circuitry means, receiving said first and second output signal, for controlling delivery of cardiac pacing pulses, and for causing a cardiac pacing pulse to be delivered from said electrode at a first stimulating energy level if said first output signal is not asserted within a first predetermined time interval following assertion of said second output signal; said controlling circuitry means further causing a cardiac pacing pulse to be delivered at a second stimulating energy level, higher than said first stimulating energy level, if said second output signal is not asserted within a second predetermined time interval following assertion of said first output signal.

Claim 5

A method of pacing a patient's heart via a single pacing/sensing electrode comprising the steps of: (a) disposing said electrode in a venous channel of said heart; (b) applying cardiac signals received by said electrode to inputs of first and second sense amplifiers having first and second sensing thresholds voltages, respectively, said first sensing threshold voltage being lower than said second sensing threshold voltage; (c) asserting an atrial event indicating signal when said cardiac signals exceed the sensing threshold of said first sense amplifier and do not exceed the sensing threshold of said second sense amplifier; (d) asserting a ventricular event indicating signal when said cardiac signals exceed the sensing thresholds of both said first and second sense amplifier; (e) delivering a pacing pulse from said electrode at a first, lower stimulating energy level if said atrial event indicating signal is not asserted within a first predetermined time interval following assertion of said ventricular event indicating signal; and (f) delivering a pacing pulse from said electrode at a second, higher stimulating energy level if said ventricular event indicating signal is not asserted within a second predetermined time interval following assertion of said atrial event indicating signal.

Claim 6

A method of pacing a patient's heart via a single pacing/sensing electrode comprising the steps of: (a) disposing said electrode in a venous channel of said heart; (b) applying cardiac signals received by said electrode to inputs of first and second sense amplifiers having first and second sensing thresholds voltages, respectively, said first sensing threshold voltage being lower than said second sensing threshold voltage; (c) asserting an atrial event indicating signal when said cardiac signals exceed the sensing threshold of said first sense amplifier and do not exceed the sensing threshold of said second sense amplifier; (d) asserting a ventricular event indicating signal when said cardiac signals exceed the sensing thresholds of both said first and second sense amplifier; (e) delivering a pacing pulse from said electrode at a first, lower stimulating energy level if said atrial event indicating signal is not asserted within a first predetermined time interval following assertion of said ventricular event indicating signal; and (f) delivering a pacing pulse from said electrode at a second, higher stimulating energy level if said ventricular event indicating signal is not asserted within a second predetermined time interval following assertion of said atrial event indicating signal.

Claim 12

A method of pacing a patients heart via a single pacing/sensing electrode comprising the steps of: (a) disposing said electrode in a venous channel of said heart; (b) applying electrical cardiac signals received by said electrode to the input of a sense amplifier having a selectable sensing threshold voltage; (c) initially setting the sensing threshold voltage of said sense amplifier to a first level; (d) asserting a ventricular event indicating signal if said electrical cardiac signals exceed said first sensing threshold voltage level within a first predetermined time period following assertion of an atrial event indicating signal; (e) delivering a cardiac stimulating pulse from said electrode at a first stimulating energy level if said electrical cardiac signals do not exceed said first sensing threshold voltage level within said first predetermined time interval following assertion of said atrial event indicating signal; (f) re-setting the sensing threshold voltage of said sense amplifier to a second threshold voltage level, lower than said first sensing threshold voltage level, if said ventricular event indicating signal is asserted and if a cardiac stimulating pulse is delivered at said first stimulating voltage level; (g) asserting an atrial event indicating signal if said electrical cardiac signals exceed said second sensing threshold voltage level within a second predetermined time interval; (h) delivering a cardiac stimulating pulse from said electrode at a second stimulating energy level, lower than said first stimulating voltage level, if said electrical cardiac signals do not exceed said second sensing threshold voltage level within said second predetermined time interval; (i) re-setting the sensing threshold voltage of said sense amplifier to said first sensing threshold level if said atrial event indicating signal is asserted and if a cardiac stimulating pulse is delivered at said second, lower stimulating voltage level; (j) continuously repeating steps (d) through (i) above.

Claim 13

A method of pacing a patients heart via a single pacing/sensing electrode comprising the steps of: (a) disposing said electrode in a venous channel of said heart; (b) applying electrical cardiac signals received by said electrode to the input of a sense amplifier having a selectable sensing threshold voltage; (c) initially setting the sensing threshold voltage of said sense amplifier to a first level; (d) asserting a ventricular event indicating signal if said electrical cardiac signals exceed said first sensing threshold voltage level within a first predetermined time period following assertion of an atrial event indicating signal; (e) delivering a cardiac stimulating pulse from said electrode at a first stimulating energy level if said electrical cardiac signals do not exceed said first sensing threshold voltage level within said first predetermined time interval following assertion of said atrial event indicating signal; (f) re-setting the sensing threshold voltage of said sense amplifier to a second threshold voltage level, lower than said first sensing threshold voltage level, if said ventricular event indicating signal is asserted and if a cardiac stimulating pulse is delivered at said first stimulating voltage level; (g) asserting an atrial event indicating signal if said electrical cardiac signals exceed said second sensing threshold voltage level within a second predetermined time interval; (h) delivering a cardiac stimulating pulse from said electrode at a second stimulating energy level, lower than said first stimulating voltage level, if said electrical cardiac signals do not exceed said second sensing threshold voltage level within said second predetermined time interval; (i) re-setting the sensing threshold voltage of said sense amplifier to said first sensing threshold level if said atrial event indicating signal is asserted and if a cardiac stimulating pulse is delivered at said second, lower stimulating voltage level; (j) continuously repeating steps (d) through (i) above.

Claim 16

A method of pacing the atrium and ventricle of a human heart, comprising: locating an electrode with respect to said human heart in a position such that the pacing threshold of said atrium of said human heart, at said position, is lower than the pacing threshold of said ventricle of said human heart, at said position; and sequentially delivering pacing pulses to said electrode to stimulate said atrium and said ventricle, said pacing pulses comprising a first pulse delivered at a level in excess of said pacing threshold of said atrium but less than said pacing threshold of said ventricle, followed by a second pulse delivered at a level in excess of said pacing threshold of said ventricle.

Claim 17

A method of pacing the atrium and ventricle of a human heart, comprising: locating an electrode with respect to said human heart in a position such that the pacing threshold of said atrium of said human heart, at said position, is lower than the pacing threshold of said ventricle of said human heart, at said position; and sequentially delivering pacing pulses to said electrode to stimulate said atrium and said ventricle, said pacing pulses comprising a first pulse delivered at a level in excess of said pacing threshold of said atrium but less than said pacing threshold of said ventricle, followed by a second pulse delivered at a level in excess of said pacing threshold of said ventricle.

Claim 20

A method of pacing the ventricle of a human heart in synchrony with the atrium of a human heart, comprising: locating an electrode in a position adjacent the atrium and ventricle of said human heart, at which electrical signals from said atrium of said human heart may be sensed and at which stimulation of said ventricle of said human heart may be accomplished; sensing electrical activity of the atrium of said human heart; and following sensing of electrical activity in the atrium of said human heart, using said electrode, delivering a pacing pulse to said electrode to stimulate the ventricle of said human heart.

Claim 21

A method of pacing the ventricle of a human heart in synchrony with the atrium of a human heart, comprising: locating an electrode in a position adjacent the atrium and ventricle of said human heart, at which electrical signals from said atrium of said human heart may be sensed and at which stimulation of said ventricle of said human heart may be accomplished; sensing electrical activity of the atrium of said human heart; and following sensing of electrical activity in the atrium of said human heart, using said electrode, delivering a pacing pulse to said electrode to stimulate the ventricle of said human heart.