US5263323A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Heat-activated drug delivery system and thermal actuators therefor
Assignee: Individual
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Filing: 1992-04-02
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Granted: 1993-11-23
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Expires: 2012-04-02
Abstract
Abstract A thermal actuator, also known as a heat capacitance motor, derives its energy from the physical expansion of paraffin wax as it changes from solid to liquid when heated within an enclosure such as a cylinder. This energy is converted into mechanical force which causes translation of a piston slidably mounted within the cylinder, thus creating hydrostatic pressure which is converted to work. The thermal actuator may be utilized in various drug delivery systems in which the hydrostatic pressure created by the actuator is used expel the contents of a syringe.
Inventors
- 👤 Daryl D. Maus
- 👤 Scott F. Tibbitts
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 18:53
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/142; A61M5/145; A61M5/1452; A61M5/14526; F; F03; F03G; F03G7/00; F03G7/06; F03G7/061; F03G7/06112; F03G7/06113; F03G7/062; F03G7/064; A61M2205/00; A61M2205/33; A61M2205/3368; A61M2205/36; A61M2205/3613; A61M2205/3653; A61M5/14244; A61M5/168; A61M5/16831; F03G7/066
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
112 words
An infusion system for dispensing a fluid, said system comprising: a) an enclosure defining an interior chamber and having an outlet formed at one end; b) a syringe piston mounted for movement within said chamber, the portion of said interior chamber between said syringe piston and said outlet defining a variable volume compartment for containing a fluid; and c) motive means for causing said syringe piston to move toward said outlet, forcing said fluid out of said variable volume compartment, said motive means including: i) a thermally responsive expansion material for creating hydraulic pressure in response to a temperature increase, and ii) actuator means for converting said hydraulic pressure into linear motion.
Claim 2
Dependent Claim
112 words
An infusion system for dispensing a fluid, said system comprising: a) an enclosure defining an interior chamber and having an outlet formed at one end; b) a syringe piston mounted for movement within said chamber, the portion of said interior chamber between said syringe piston and said outlet defining a variable volume compartment for containing a fluid; and c) motive means for causing said syringe piston to move toward said outlet, forcing said fluid out of said variable volume compartment, said motive means including: i) a thermally responsive expansion material for creating hydraulic pressure in response to a temperature increase, and ii) actuator means for converting said hydraulic pressure into linear motion.
Claim 3
Dependent Claim
15 words
An infusion system according to claim 1, wherein said thermally responsive expansion material comprises paraffin.
Claim 4
Dependent Claim
25 words
An infusion system according to claim 1, wherein said thermally responsive material comprises a material which undergoes a solid-liquid phase change at a predetermined temperature.
Claim 5
Dependent Claim
17 words
An infusion system according to claim 3, wherein said predetermined temperature is less than human body temperature.
Claim 6
Dependent Claim
25 words
An infusion system according to claim 1, further comprising control means for controlling heat flux into said system to control the fluid delivery rate thereof.
Claim 7
Dependent Claim
25 words
An infusion system according to claim 5, wherein said thermally responsive material comprises a material which undergoes a solid-liquid phase change at a predetermined temperature.
Claim 8
Dependent Claim
53 words
An infusion system according to claim 6, wherein said control means comprises an isothermal shell surrounding said motive means for slowing the rate of temperature increase of said expansion material, said isothermal shell comprising a second thermal expansion material which undergoes a solid-liquid phase change at a temperature higher than said predetermined temperature.
Claim 9
Dependent Claim
20 words
An infusion system according to claim 6, wherein said control means comprises means for maintaining a vacuum in said chamber.
Claim 10
Dependent Claim
49 words
An infusion system according to claim 5, wherein said control means comprises: a) an electrically heated isothermal shell surrounding said motive means; and b) a layer of insulation material interposed between said motive means and said isothermal shell for slowing the rate of temperature increase of said expansion material.
Claim 11
Dependent Claim
63 words
An infusion system according to claim 5, wherein said control means comprises: a) temperature sensing means for measuring the temperature within said enclosure; b) heating means in thermal contact with said motive means; and c) control means coupled to said temperature sensing means and said heating means for selectively energizing and de-energizing said heating means in response to temperature changes in said enclosure.
Claim 12
Dependent Claim
76 words
An infusion system according to claim 5, wherein said control means comprises: a) motion detector means for detecting the relative movement of said discharge assistant relative to said enclosure; b) heating means in thermal contact with said motive means; and c) control means coupled to said motion detector means and said heating means for selectively energizing and de-energizing said heating means in response to the rate of movement of said discharge assistant relative to said enclosure.
Claim 13
Dependent Claim
36 words
An infusion system according to claim 6, wherein said control means comprises an insulating jacket surrounding said motive means, the thermal resistance of said insulating jacket varying in direct proportion to changes in the ambient temperature.
Claim 14
Dependent Claim
91 words
An infusion system according to claim 5, wherein said jacket comprises: a) a plurality of neighboring segments, each segment being formed of expandable thermal insulation material; and b) gap means formed between said neighboring segments when said the temperature of said jacket is below ambient temperature and segments are in an unexpanded state, said gap means communicating with ambient air to allow said air to reach said motive means and heat said segments, causing said segments to expand and seal said gap means to reduce heat flow to said motive means.
References Cited (Backward Citations)
US4899910A
Cited
US5025627A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-11-22 | 1997-05-24 | 1997-11-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-11-22 | 2001-05-24 | 2001-11-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-11-22 | 2005-05-24 | 2005-11-23 | $7700.00 | Window Closed / Lapsed |