US5240703A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Attenuated, genetically-engineered pseudorabies virus s-prv-155 and uses thereof
Assignee: Syntro Corp
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Filing: 1991-03-01
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Granted: 1993-08-31
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Expires: 2011-03-01
Abstract
Abstract The present invention provides an attenuated, genetically-engineered pseudorabies virus designated S-PRV-155 (ATCC Accession No. VR 2311). A vaccine is provided which comprises an effective immunizing amount of S-PRV-155 and a suitable carrier. A method of immunizing an animal against disease caused by pseudorabies virus is also provided which comprises administering to the animal an effective immunizing dose of the vaccine. The present invention also provides a method for distinguishing an animal vaccinated with the vaccine of the present invention from an animal infected with a naturally-occurring, wild-type pseudorabies virus.
Inventors
- 👤 Mark D. Cochran
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 10:57
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; A; A61; A61K; A61K39/00; A61K39/12; A61K39/245; A61P; A61P31/00; A61P31/12; A61P31/20; A61P31/22; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/569; G01N33/56983; A61K2039/51; A61K2039/525; A61K2039/5252; A61K2039/5254; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16711; C12N2710/16722; C12N2710/16734; Y; Y10; Y10S; Y10S424/00; Y10S424/815
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
25 words
A vaccine which comprises an effective immunizing amount of an attenuated, genetically-engineered pseudorabies virus designated S-PRV-155 (ATCC Accession No. VR 2311) and a suitable carrier.
Claim 2
Dependent Claim
25 words
A vaccine which comprises an effective immunizing amount of an attenuated, genetically-engineered pseudorabies virus designated S-PRV-155 (ATCC Accession No. VR 2311) and a suitable carrier.
Claim 3
Dependent Claim
11 words
A vaccine of claim 1, wherein the attenuated virus is inactivated.
Claim 4
Dependent Claim
11 words
A vaccine of claim 1, wherein the attenuated virus is live.
Claim 5
Dependent Claim
17 words
A vaccine of claim 1, wherein the carrier is a physiologically balanced culture medium containing stabilizing agents.
Claim 6
Dependent Claim
20 words
A vaccine of claim 1, wherein the effective immunizing amount is from about 10 3 to about 10 9 PFU/dose.
Claim 7
Dependent Claim
20 words
A vaccine of claim 5, wherein the effective immunizing amount is from about 10 4 to about 10 6 PFU/dose.
Claim 8
Dependent Claim
20 words
A vaccine of claim 5, wherein the effective immunizing amount is from about 10 7 to about 10 9 PFU/dose.
Claim 9
Dependent Claim
28 words
A method of immunizing an animal against disease caused by pseudorabies virus which comprises administering to the animal an effective immunizing dose of the vaccine of claim 1.
Claim 10
Dependent Claim
11 words
A method of claim 8, wherein the animal is a swine.
Claim 11
Dependent Claim
17 words
A method of claim 8, wherein the vaccine is administered by intramuscular, subcutaneous, intraperitoneal or intravenous injection.
Claim 12
Dependent Claim
11 words
A method of claim 8, wherein the vaccine is administered intranasally.
Claim 13
Dependent Claim
11 words
A method of claim 8, wherein the vaccine is administered orally.
References Cited (Backward Citations)
US4769331A
Cited
US4680176A
Cited
US4514497A
Cited
US4514497B1
Cited
US5041536A
Cited
US5041370A
Cited
US4810634A
Cited
US4877737A
Cited
US5047237A
Cited
US5068192A
Cited
US4711850A
Cited
US4999296A
Cited
US5037742A
Cited
US5004593A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1996-08-30 | 1997-03-01 | 1997-08-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-08-30 | 2001-03-01 | 2001-08-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-08-30 | 2005-03-01 | 2005-08-31 | $7700.00 | Window Closed / Lapsed |