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US5236703A Expired / Lapsed US ⏱️ 0.0 years remaining

Polymeric substrates containing povidone-iodine as a control release biologically active agent

Assignee: Immunix Inc
•
Filing: 1989-07-20
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Granted: 1993-08-17
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Expires: 2009-07-20
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Abstract

Abstract A polymeric substrate such as rubber or latex incorporates povidone-iodine as a control release biologically active agent.

Inventors

  • 👤 Anton-Lewis Usala

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 07:29
CPC Classifications
A; A01; A01N; A01N59/00; A01N59/12; A61; A61L; A61L29/00; A61L29/14; A61L29/16; A61L31/00; A61L31/14; A61L31/16; C; C09; C09D; C09D121/00; C09D121/02; A61L2300/00; A61L2300/20; A61L2300/202; A61L2300/40; A61L2300/404; A61L2300/60; A61L2300/602; Y; Y10; Y10T; Y10T428/00; Y10T428/28

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 133 words
A polymeric film which control-releases a biologically active agent while in contact with a polar liquid to prevent the contamination and penetration of pathogens through said film, comprising: at least one layer of said polymeric film having dispersed therein povidone-iodine in the range of about 0.01% to 25% as said biologically active agent; said polymeric film prepared from a dispersion of said povidone-iodine and a film-forming polymeric material prepared by homopolymerization or copolymerization of ethylene monomers or monomers having at least two conjugated double bonds and capable of being vulcanized or cross-linked, said polymeric film being heated at elevated temperatures for a length of time varying with respect to the temperature and the amount of said povidone-iodine to control the release of said povidone-iodine from said film upon contact with said polar liquid.
Claim 2
Dependent Claim 133 words
A polymeric film which control-releases a biologically active agent while in contact with a polar liquid to prevent the contamination and penetration of pathogens through said film, comprising: at least one layer of said polymeric film having dispersed therein povidone-iodine in the range of about 0.01% to 25% as said biologically active agent; said polymeric film prepared from a dispersion of said povidone-iodine and a film-forming polymeric material prepared by homopolymerization or copolymerization of ethylene monomers or monomers having at least two conjugated double bonds and capable of being vulcanized or cross-linked, said polymeric film being heated at elevated temperatures for a length of time varying with respect to the temperature and the amount of said povidone-iodine to control the release of said povidone-iodine from said film upon contact with said polar liquid.
Claim 3
Dependent Claim 16 words
The polymeric film as recited in claim 1 wherein said film-forming polymeric material is latex rubber.
Claim 4
Dependent Claim 36 words
The polymeric film as recited in claim 1 further characterized as comprising at least two layers of the polymeric film, one of said layers having a larger amount of povidone-iodine in comparison with the other layers.
Claim 5
Dependent Claim 32 words
The polymeric film as recited in claim 1 further characterized as comprising at least two layers of the polymeric film with about 0.01 to 10% by weight of povidone-iodine in each layer.
Claim 6
Dependent Claim 31 words
The polymeric film as recited in claim 4 wherein at least one of said layers of the polymeric film has dispersed therein a larger amount of povidone-iodine than the other layers.
Claim 7
Dependent Claim 54 words
The polymeric film as recited in claim 1 further characterized as comprising a plurality of layers of polymeric film at least one layer of said plurality of layers having dispersed therein a different amount of povidone-iodine and heated for a different length of time at a different temperature in comparison with the other layers.
Claim 8
Dependent Claim 52 words
A latex substrate comprising: a heat cured latex rubber having bonded thereto a predetermined amount of povidone-iodine substantially through van der Waals bonds by controlled heating thereby enabling local release of said povidone-iodine therefrom upon contact with a polar liquid, said predetermined amount being in the range of about 0.01% to 25%.
Claim 9
Dependent Claim 52 words
A latex substrate comprising: a heat cured latex rubber having bonded thereto a predetermined amount of povidone-iodine substantially through van der Waals bonds by controlled heating thereby enabling local release of said povidone-iodine therefrom upon contact with a polar liquid, said predetermined amount being in the range of about 0.01% to 25%.
Claim 10
Dependent Claim 55 words
A latex substrate comprising: a film layer of cured latex rubber incorporating povidone-iodine therewithin formed from a mixture comprising said latex rubber and said povidone-iodine, said mixture being processed to a predetermined exclusion of covalent bonding between said latex rubber and said povidone-iodine, said povidone-iodine being present in the amount of about 0.1% to 10%.
Claim 11
Dependent Claim 55 words
A latex substrate comprising: a film layer of cured latex rubber incorporating povidone-iodine therewithin formed from a mixture comprising said latex rubber and said povidone-iodine, said mixture being processed to a predetermined exclusion of covalent bonding between said latex rubber and said povidone-iodine, said povidone-iodine being present in the amount of about 0.1% to 10%.
Claim 12
Dependent Claim 69 words
A latex rubber substrate comprising: a latex rubber and an effective amount of povidone-iodine formed from a mixture comprising said latex and said povidone-iodine, said povidone-iodine being in the amount of about 0.01% to 25% and functioning as a vulcanizing and cross linking agent upon heating of said mixture at temperatures below about 400° to permit release of said povidone-iodine as an antimicrobial upon contact with a polar liquid.
Claim 13
Dependent Claim 69 words
A latex rubber substrate comprising: a latex rubber and an effective amount of povidone-iodine formed from a mixture comprising said latex and said povidone-iodine, said povidone-iodine being in the amount of about 0.01% to 25% and functioning as a vulcanizing and cross linking agent upon heating of said mixture at temperatures below about 400° to permit release of said povidone-iodine as an antimicrobial upon contact with a polar liquid.
Claim 14
Dependent Claim 53 words
A multilayer latex article comprising: a plurality of heat cured latex rubber substrate films, at least one of said films being a controlled release film having incorporated therewithin povidone-iodine in the range of about 0.01% to 25%, said povidone-iodine in said controlled release film having controlled van der Waals bonding with said latex.
Claim 15
Dependent Claim 53 words
A multilayer latex article comprising: a plurality of heat cured latex rubber substrate films, at least one of said films being a controlled release film having incorporated therewithin povidone-iodine in the range of about 0.01% to 25%, said povidone-iodine in said controlled release film having controlled van der Waals bonding with said latex.

References Cited (Backward Citations)

US4310509A Cited
US4500339A Cited
US4538603A Cited
US4769013A Cited
US4793337A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-08-16 1997-02-15 1997-08-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-08-16 2001-02-15 2001-08-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-08-16 2005-02-15 2005-08-17 $7700.00 Window Closed / Lapsed

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