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US5222503A
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Ambulatory electroencephalography system
Assignee: Beth Israel Hospital Association A Non Profit Corp Of Ma
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Filing: 1991-04-24
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Granted: 1993-06-29
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Expires: 2011-04-24
Abstract
Abstract An ambulatory electroencephalography (EEG) system includes a self-powered recording apparatus adapted to be worn by a patient. The recording apparatus includes an A/D converter and a digital memory capable of storing digital data representing analog waveform signals derived from a large number of electrodes secured to the patient. Recording of digital waveform data is governed by a controller, which upon the occurrence of a neurologically significant event (such as actuation of a switch by the patient or detection of EEG waveforms indicating a seizure state) causes the storage of waveform data over an interval immediately preceding the event and immediately following the event.
Inventors
- 👤 John R. Ives
- 👤 Norman R. Mainwaring
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 18:01
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/24; A61B5/316; A61B5/369; A61B5/384; A61B5/372; A61B5/40; A61B5/4076; A61B5/4094
Claims Analysis
Total Claims: 55
Claim 1
Independent Claim
310 words
A system for unattended ambulatory neurological monitoring of a patient comprising a neurological signal recording apparatus adapted to be worn by a patient during a monitoring procedure and operable when worn without electrical connection to any apparatus not worn by the patient, said recording apparatus including: an input means for receiving a plurality of analog EEG signals, each derived from one pair of a plurality of pairs of electrodes coupled to a patient's head; an A/D converter means having a converter input coupled to the apparatus input means and a converter output, said A/D converter means producing digital signals at said converter output which represent the waveforms of analog signals received at said converter input; a digital memory means coupled to said converter output for storing digital data representing the waveforms of said analog EEG signals, said memory means storing all stored signals in digital form; a controller means for controlling the storage of data in said memory means, said controller means causing temporary storage of data in said memory means representing the waveforms of EEG signals occurring over a predetermined interval of time representing a pre-event data storage interval and causing the periodic updating of the temporarily stored data to correspond with the data occurring in the predetermined interval immediately preceding each updating, said controller means further causing, upon the occurrence of a predetermined event, the permanent storage of data in said memory means including the temporarily stored data which represents the waveforms of EEG signals occurring over the pre-event data storage interval of time immediately preceding the event and data representing the waveforms of EEG signals occurring over an interval of time immediately following the event; a self-contained power source means for providing operating power for said recording apparatus; and an output means coupled to said memory means for outputting digital waveform data derived from said stored data.
Claim 2
Independent Claim
310 words
A system for unattended ambulatory neurological monitoring of a patient comprising a neurological signal recording apparatus adapted to be worn by a patient during a monitoring procedure and operable when worn without electrical connection to any apparatus not worn by the patient, said recording apparatus including: an input means for receiving a plurality of analog EEG signals, each derived from one pair of a plurality of pairs of electrodes coupled to a patient's head; an A/D converter means having a converter input coupled to the apparatus input means and a converter output, said A/D converter means producing digital signals at said converter output which represent the waveforms of analog signals received at said converter input; a digital memory means coupled to said converter output for storing digital data representing the waveforms of said analog EEG signals, said memory means storing all stored signals in digital form; a controller means for controlling the storage of data in said memory means, said controller means causing temporary storage of data in said memory means representing the waveforms of EEG signals occurring over a predetermined interval of time representing a pre-event data storage interval and causing the periodic updating of the temporarily stored data to correspond with the data occurring in the predetermined interval immediately preceding each updating, said controller means further causing, upon the occurrence of a predetermined event, the permanent storage of data in said memory means including the temporarily stored data which represents the waveforms of EEG signals occurring over the pre-event data storage interval of time immediately preceding the event and data representing the waveforms of EEG signals occurring over an interval of time immediately following the event; a self-contained power source means for providing operating power for said recording apparatus; and an output means coupled to said memory means for outputting digital waveform data derived from said stored data.
Claim 3
Dependent Claim
30 words
A system according to claim 1, wherein said recording apparatus includes a switch coupled to said controller means, and said predetermined event is actuation of said switch by said patient.
Claim 4
Dependent Claim
46 words
A system according to claim 1, wherein said recording apparatus includes a clock coupled to said controller means, and said controller means causes the storage of digital data representing the waveforms of EEG signals upon receipt by said controller means of a signal from said clock.
Claim 5
Dependent Claim
42 words
A system according to claim 1, wherein said recording apparatus includes signal processing apparatus coupled to said input and to said controller means, and said predetermined event is detection by said signal processing apparatus of predetermined electrical signals occurring at said input.
Claim 6
Dependent Claim
26 words
A system according to claim 4, wherein said signal processing apparatus includes means for detecting EEG signals corresponding to a waveform spike or a patient seizure.
Claim 7
Dependent Claim
15 words
A system according to claim 1, wherein said digital memory means is a semiconductor memory.
Claim 8
Dependent Claim
14 words
A system according to claim 6, wherein said digital memory means comprises static RAM.
Claim 9
Dependent Claim
15 words
A system according to claim 1, wherein said digital memory means comprises a magnetic disc.
Claim 10
Dependent Claim
22 words
A system according to claim 1, wherein said system includes artifact reduction means for reducing storage of data representing patient movement artifacts.
Claim 11
Dependent Claim
23 words
A system according to claim 9, wherein said artifact reduction means includes a digital memory which is unaffected by the patient's physical movement.
Claim 12
Dependent Claim
21 words
A system according to claim 9, wherein said artifact reduction means includes an electrical signal filter to remove EMG signal components.
Claim 13
Dependent Claim
22 words
A system according to claim 11, wherein said filter comprises an analog filter coupled to said input for filtering analog electrical signals.
Claim 14
Dependent Claim
27 words
A system according to claim 11, wherein said filter comprises a digital filter for receiving digital signals derived from said converter and producing filtered digital output signals.
Claim 15
Dependent Claim
39 words
A system according to claim 9, wherein said system includes a plurality of electrodes adapted to be coupled to a patient's body, and includes means for coupling neurological electrical signals generated by said patient to said recording apparatus input.
Claim 16
Dependent Claim
15 words
A system according to claim 14, wherein said artifact reduction means includes said coupling means.
Claim 17
Dependent Claim
31 words
A system according to claim 15, wherein said coupling means includes at least one amplifier having an input receiving said neurological signals and an output coupled to said recording apparatus input.
Claim 18
Dependent Claim
31 words
A system according to claim 16, wherein said amplifier is adapted to be mounted to the patient's head, whereby said amplifier input is close to electrodes to which it is coupled.
Claim 19
Dependent Claim
49 words
A system according to claim 17, wherein said coupling means includes a communication channel coupled to said recording apparatus input, and includes multiplexing means mounted to the patient's head and coupled to said amplifier for coupling neurological electrical signals from a plurality of said electrodes to said communication channel.
Claim 20
Dependent Claim
51 words
A system according to claim 15, wherein said amplifier is mounted in an enclosure having a curved surface having a radius of curvature in the range of about 2 inches to about 5 inches, whereby said enclosure may be placed adjacent the patient's head and generally conform to the surface thereof.
Claim 21
Dependent Claim
27 words
A system according to claim 14, wherein said artifact reduction means includes means for securing at least a portion of said coupling means to said patient's head.
Claim 22
Dependent Claim
21 words
A system according to claim 14, wherein said artifact reduction means includes adhesive means for securing said electrodes to said patient.
Claim 23
Dependent Claim
27 words
A system, according to claim 1, wherein said digital memory means includes means for separately storing data representing neurological electrical signals derived from at least 16 electrodes.
Claim 24
Dependent Claim
21 words
A system according to claim 1, wherein said digital memory means includes a storage capacity of at least about 1 Megabyte.
Claim 25
Dependent Claim
21 words
A system according to claim 23, wherein said digital memory means includes a storage capacity of at least about 4 Megabytes.
Claim 26
Dependent Claim
24 words
A system according to claim 1, wherein said recording apparatus includes means for simultaneously receiving and recording both EEG waveform signals and EKG signals.
Claim 27
Dependent Claim
49 words
A system according to claim 1, wherein said system includes a portable auxiliary computer system including auxiliary digital memory and not adapted to be worn by the patient, and also includes means for coupling said recording apparatus output to said auxiliary computer system for interchanging digital data between them.
Claim 28
Dependent Claim
35 words
A system according to claim 1, wherein said system includes a digital display generator means for receiving digital data stored in said recording apparatus and to generate a graphic digital display corresponding to received data.
Claim 29
Dependent Claim
20 words
A system according to claim 27, wherein said graphic digital display includes a graphic representation of EEG or EKG waveforms.
Claim 30
Dependent Claim
28 words
A system according to claim 27, wherein said digital display includes text representing information relating to said patient or to the neurological monitoring procedure performed on said patient.
Claim 31
Dependent Claim
16 words
A system according to claim 27, wherein said digital display generator means includes a laser printer.
Claim 32
Dependent Claim
25 words
A system according to claim 27, wherein said graphic display includes a representation of locations of said electrodes on said patient during the monitoring procedure.
Claim 33
Dependent Claim
28 words
A system according to claim 1, wherein said system includes means for storing data relating to said patient or to the neurological monitoring procedure performed on said patients.
Claim 34
Independent Claim
139 words
A method of determining the neurological condition of a patient comprising the steps of: a. when a patient is in a first location, securing a plurality of electrodes to the patient, said electrodes producing analog neurological electrical signals relating to said patient; b. securing a recording apparatus including a digital memory to said patient; c. coupling said electrodes to said recording apparatus; d. when the patient is in a second location different from the first location, recording digital data in said memory including data responsive to said analog neurological electrical signals produced by said patient; e. when the recording apparatus is in a third location, transferring digital data stored in recording step d to a computer system including a graphic display generator; and f. generating a graphic digital display representing data transferred to said computer system in step e.
Claim 35
Independent Claim
139 words
A method of determining the neurological condition of a patient comprising the steps of: a. when a patient is in a first location, securing a plurality of electrodes to the patient, said electrodes producing analog neurological electrical signals relating to said patient; b. securing a recording apparatus including a digital memory to said patient; c. coupling said electrodes to said recording apparatus; d. when the patient is in a second location different from the first location, recording digital data in said memory including data responsive to said analog neurological electrical signals produced by said patient; e. when the recording apparatus is in a third location, transferring digital data stored in recording step d to a computer system including a graphic display generator; and f. generating a graphic digital display representing data transferred to said computer system in step e.
Claim 36
Dependent Claim
17 words
A method according to claim 33, wherein said first location and said third location are the same.
Claim 37
Dependent Claim
22 words
A method according to claim 33, wherein said securing step a includes securing at least about 16 electrodes to the patient's head.
Claim 38
Dependent Claim
26 words
A method according to claim 35, wherein said securing step a further includes securing at least one electrode to the patient's chest adjacent the patient's heart.
Claim 39
Dependent Claim
18 words
A method according to claim 33, wherein said securing step a includes gluing electrodes to said patient's skin.
Claim 40
Dependent Claim
21 words
A method according to claim 37, wherein said predetermined conditions include derived signals corresponding spike or seizure conditions of said patient.
Claim 41
Dependent Claim
37 words
A method according to claim 33, wherein said coupling step includes providing one or more conductors coupled to said electrodes and to said recording apparatus, and securing at least a portion of said conductors to said patient.
Claim 42
Dependent Claim
29 words
A method according to claim 33, wherein said securing step b includes securing to said patient a recording apparatus having a memory size of at least about 1 Megabyte.
Claim 43
Dependent Claim
17 words
A method according to claim 33, wherein said coupling step includes amplification of analog neurological electrical signals.
Claim 44
Dependent Claim
37 words
A method according to claim 41, wherein said coupling step includes disposing an amplifier contained in a curved housing, having a radius of curvature of between about 2 inches and about 5 inches, adjacent said patient's head.
Claim 45
Dependent Claim
27 words
A method according to claim 33, wherein said coupling step includes multiplexing of electrical signals derived from a plurality of said electrodes into a single communication channel.
Claim 46
Dependent Claim
16 words
A method according to claim 33, wherein said recording step includes an EMG signal filtration step.
Claim 47
Dependent Claim
13 words
A method according to claim 33, wherein said filtration step includes digital filtering.
Claim 48
Dependent Claim
30 words
A method according to claim 33, wherein said recording step includes recording digital data responsive to said analog electrical signals occurring over a period of at least about 12 hours.
Claim 49
Dependent Claim
23 words
A method according to claim 33, wherein said recording step includes recording data in response to a recording signal provided by said patient.
Claim 50
Dependent Claim
32 words
A method according to claim 33, wherein said recording step includes analyzing signals derived from said analog neurological electrical signals, and recording data in response to predetermined conditions of said derived signals.
Claim 51
Dependent Claim
17 words
A method according to claim 33, wherein said recording step includes intermittently recording data at predetermined times.
Claim 52
Dependent Claim
17 words
A method according to claim 33, wherein said display generating step includes generating a laser printed output.
Claim 53
Dependent Claim
21 words
A method according to claim 33, wherein said display generating step includes generating a graphic representation of EEG or EKG waveforms.
Claim 54
Dependent Claim
29 words
A method according to claim 33, wherein said display generating step includes generating text representing information relating to said patient or the neurological monitoring procedure performed on said patient.
Claim 55
Dependent Claim
29 words
A method according to claim 52, wherein said display generating step includes generating a graphic representation of the locations of said electrodes on said patient during said monitoring procedure.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-06-28 | 1996-12-28 | 1997-06-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-06-28 | 2000-12-28 | 2001-06-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-06-28 | 2004-12-28 | 2005-06-29 | $7700.00 | Window Closed / Lapsed |