US5208144A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for detection of human dna containing the gene encoding low density lipoprotein receptor
Assignee: General Hospital Corp
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Filing: 1989-08-22
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Granted: 1993-05-04
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Expires: 2009-08-22
Abstract
Abstract A method for the detection of a genetic abnormality in the LDL receptor gene, by hybridization of such gene with a DNA sequence encoding gp330.
Inventors
- 👤 John A. Smith
- 👤 Raktima Raychowdhury
- 👤 John L. Niles
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 09:14
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/11; C12Q; C12Q1/00; C12Q1/68; C12Q1/6876; C12Q1/6883; A; A61; A61P; A61P1/00; A61P1/04; C07; C07K; C07K14/00; C07K14/435; C07K14/705; C07K16/00; C07K16/18; C07K16/28; A61K; A61K38/00; C12Q2600/00; C12Q2600/156
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
104 words
A method for the detection of human DNA which contains the gene encoding low density lipoprotein receptor, said method comprising (a) isolating DNA that contains said DNA which contains the gene encoding low density lipoprotein receptor from a human; (b) contacting said DNA obtained in step (a) with DNA encoding gp330 under for a time and under conditions sufficient for hybridization to occur; and (c) detecting hybridization of said DNA which contains the gene encoding gp330 DNA with said low density lipoprotein receptor whereby the presence of said hybridization indicates the presence of DNA which contains the gene encoding the low density lipoprotein receptor.
Claim 2
Independent Claim
104 words
A method for the detection of human DNA which contains the gene encoding low density lipoprotein receptor, said method comprising (a) isolating DNA that contains said DNA which contains the gene encoding low density lipoprotein receptor from a human; (b) contacting said DNA obtained in step (a) with DNA encoding gp330 under for a time and under conditions sufficient for hybridization to occur; and (c) detecting hybridization of said DNA which contains the gene encoding gp330 DNA with said low density lipoprotein receptor whereby the presence of said hybridization indicates the presence of DNA which contains the gene encoding the low density lipoprotein receptor.
References Cited (Backward Citations)
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WO1985000369A1
Cited
EP0177915A2
Cited
WO1986004090A1
Cited
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Cited
EP0234888A2
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-05-03 | 1996-11-02 | 1997-05-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-05-03 | 2000-11-02 | 2001-05-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-05-03 | 2004-11-02 | 2005-05-04 | $7700.00 | Window Closed / Lapsed |