US5204525A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Capillary flow device
Assignee: Roche Diagnostics Operations Inc
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Filing: 1991-07-19
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Granted: 1993-04-20
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Expires: 2011-07-19
Abstract
Abstract Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.
Inventors
- 👤 Robert S. Hillman
- 👤 Michael E. Cobb
- 👤 Jimmy D. Allen
- 👤 Ian Gibbons
- 👤 Vladimir E. Ostoich
- 👤 Laura J. Winfrey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 21:53
CPC Classifications
B; B29; B29C; B29C65/00; B29C65/02; B29C65/08; B01; B01F; B01F23/00; B01F23/50; B01F23/56; B01F25/00; B01F25/40; B01F25/42; B01F25/43; B01F25/431; B01F25/4316; B01F25/433; B01F25/4338; B01F33/00; B01F33/30; B01F35/00; B01F35/71; B01F35/717; B01F35/7172; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B29C66/00; B29C66/01; B29C66/05; B29C66/302; B29C66/3022; B29C66/30223; B29C66/50; B29C66/51; B29C66/54; G; G01; G01N; G01N21/00; G01N21/75; G01N21/77; G01N21/82; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; G01N33/4905; G01N33/50; G01N33/86; B01F21/00; B01F2101/00; B01F2101/23; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0816; B01L2300/0825; B01L2300/0861; B01L2300/087; B01L2300/0887; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; B29C45/00; B29C59/00; B29C59/16; B29C65/48; B29C65/4895; B29C66/70; B29C66/71; B29C66/73; B29C66/739; B29C66/7392; B29C66/73921; B29C66/90; B29C66/95; B29C66/951; B29C66/9513; B29K; B29K2055/00; B29K2055/02; B29L; B29L2031/00; B29L2031/756; G01N15/00; G01N15/10; G01N15/1012; G01N2015/1016; G01N21/01; G01N21/03; G01N2021/0346; G01N35/00; G01N2035/00465; G01N2035/00514; G01N21/17; G01N21/47; G01N21/49; G01N33/53; G01N33/543; G01N33/54366
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
136 words
A quality control device for use in an analytical instrument which utilizes an analysis cartridge containing an internal chamber in which said analysis occurs, said analysis cartridge being insertable into a location in said instrument so that light generated in said instrument passes through said chamber and is detected by a light detector in said instrument, which comprises: a control cartridge, wherein said control cartridge is insertable in said location; a liquid crystal cell located in said control cartridge so as to interpose between said light source and a light detector in said analytical instrument; and a polarizing filter located between said said light source and said light detector so as to allow passage or block passage of light between said light source and said light detector when voltage applied to said liquid crystal is modulated.
Claim 2
Dependent Claim
136 words
A quality control device for use in an analytical instrument which utilizes an analysis cartridge containing an internal chamber in which said analysis occurs, said analysis cartridge being insertable into a location in said instrument so that light generated in said instrument passes through said chamber and is detected by a light detector in said instrument, which comprises: a control cartridge, wherein said control cartridge is insertable in said location; a liquid crystal cell located in said control cartridge so as to interpose between said light source and a light detector in said analytical instrument; and a polarizing filter located between said said light source and said light detector so as to allow passage or block passage of light between said light source and said light detector when voltage applied to said liquid crystal is modulated.
Claim 3
Dependent Claim
17 words
The quality control device of claim 1, wherein said polarizing filter is located in said control cartridge.
Claim 4
Dependent Claim
16 words
The quality control device of claim 1, wherein said polarizing filter is located is said instrument.
References Cited (Backward Citations)
SE376300B
Cited
US3799742A
Cited
US4135819A
Cited
US4088448A
Cited
US4053785A
Cited
US4964728A
Cited
US4233029A
Cited
US4492462A
Cited
US4876069A
Cited
DE3134611A1
Cited
US4948961A
Cited
US4963498A
Cited
US5004923A
Cited
US4849340A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-04-19 | 1996-10-19 | 1997-04-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-04-19 | 2000-10-19 | 2001-04-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-04-19 | 2004-10-19 | 2005-04-20 | $7700.00 | Window Closed / Lapsed |