US5196404B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Inhibitors of thrombin
Assignee: Biogen MA Inc
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Filing: 1990-07-06
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Granted: 1996-09-10
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Expires: 2010-07-06
Abstract
Abstract This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 ANGSTROM in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.
Inventors
- 👤 John M Maraganore
- 👤 John W Ii Fenton
- 👤 Toni Kline
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:05
CPC Classifications
C; C07; C07K; C07K14/00; C07K7/00; C07K7/02; A; A61; A61P; A61P29/00; A61P35/00; A61P7/00; A61P7/02; C07K14/81; C07K14/815; A61K; A61K38/00; Y; Y10; Y10S; Y10S436/00; Y10S436/804; Y10S623/00; Y10S623/92
Claims Analysis
Total Claims: 0
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References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-09-10 | 2000-03-11 | 2000-09-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-09-10 | 2004-03-11 | 2004-09-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-09-10 | 2008-03-11 | 2008-09-10 | $7700.00 | Window Closed / Lapsed |