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US5188098A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and apparatus for ECG gated ventilation

Assignee: University of Pennsylvania
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Filing: 1991-11-04
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Granted: 1993-02-23
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Expires: 2011-11-04
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Abstract

Abstract Method and apparatus for maximizing the volume of blood pumped by a heart and maximizing ventilation/perfusion matching in the lungs, wherein the lungs are ventilated by a respirator in response to a control signal, are shown to include a series of monitors for generating a heart signal such as an electrocardiogram, a lung air flow rate signal and a lung air pressure signal and a controller, connected to receive these signals and to the respirator. The controller monitors the signals and generates the control signal when the heart signal is representative of a desired in point in the pumping cycle of the heart and the other signals indicate desired flow rate and pressure in the lungs. In a preferred embodiment, the control signal is generated so as to maximize the augmentation of the pumping of the heart and to minimize the trapping of air in the lungs. Using the present invention, blood being pumped from the heart is assisted by the ventilation of the lungs. It is preferred for the controller to include a series of threshold detectors for detecting when the signals exceed threshold levels. It is especially preferred for the detector to detect a point during ventricular contraction. It is especially preferred for the apparatus to further include a delay mechanism, interposed between the respirator and the controller, for delaying the control signal.

Inventors

  • 👤 Eric A. Hoffman
  • 👤 C. William Hanson, III

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:56
CPC Classifications
A; A61; A61M; A61M16/00; A61M16/021; A61M16/022; A61M16/024; A61M16/0003; A61M2016/0015; A61M2016/0018; A61M2016/0021; A61M2230/00; A61M2230/04

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 148 words
Apparatus for maximizing the volume of blood pumped by a heart, wherein the lungs associated with said heart are ventilated by a respirator, wherein said respirator causes ventilation of said lungs in response to a control signal, said apparatus comprising: a first monitor for generating a heart signal representative of the action of said heart; a second monitor for generating a flow rate signal representative of the rate of flow of air into and out of said lungs; a third monitor for generating a pressure signal representative of the air pressure in said lungs; and a controller, connected to receive said heart signal, said flow rate signal, said pressure signal and to said respirator, for generating said control signal in response to said heart signal, said flow rate signal and said pressure signal, whereby blood being pumped from the heart is assisted by the ventilation of said lungs.
Claim 2
Dependent Claim 148 words
Apparatus for maximizing the volume of blood pumped by a heart, wherein the lungs associated with said heart are ventilated by a respirator, wherein said respirator causes ventilation of said lungs in response to a control signal, said apparatus comprising: a first monitor for generating a heart signal representative of the action of said heart; a second monitor for generating a flow rate signal representative of the rate of flow of air into and out of said lungs; a third monitor for generating a pressure signal representative of the air pressure in said lungs; and a controller, connected to receive said heart signal, said flow rate signal, said pressure signal and to said respirator, for generating said control signal in response to said heart signal, said flow rate signal and said pressure signal, whereby blood being pumped from the heart is assisted by the ventilation of said lungs.
Claim 3
Independent Claim 30 words
The apparatus of claim wherein said controller comprises a plurality of threshold detectors for detecting when said heart signal, said flow rate signal and said pressure signal exceed threshold levels.
Claim 4
Dependent Claim 23 words
The apparatus of claim 2, wherein said first monitor comprises an electro cardiogram signal generator, whereby said heart signal comprises an electrocardiogram signal.
Claim 5
Dependent Claim 46 words
The apparatus of claim 2, wherein said heart comprises a Ventricle and wherein said electrocardiogram signal is representative of the contraction of said ventricle, said threshold level representative of a point during said ventricular contraction, so that said detector detects a particular point during ventricular contraction.
Claim 6
Dependent Claim 38 words
The apparatus of claim 4, wherein each of said detectors comprises a comparator and a variable reference signal generator, whereby the comparator compares a monitor generated signal to a signal generated by the associated variable reference signal generator.
Claim 7
Dependent Claim 22 words
The apparatus of claim 1, wherein said controller comprises delay means for delaying the provision of said control signal to said respirator.
Claim 8
Dependent Claim 22 words
The apparatus of claim 6, wherein said delay means is operative in response to said flow rate signal and said pressure signal.
Claim 9
Independent Claim 111 words
A system for maximizing the volume of blood pumped by a heart or optimizing ventilation/perfusion matching in the lungs, said system comprising: a programmable respirator for ventilating lungs associated with said heart, wherein said respirator causes inspiration in response to a control signal, a monitor for generating a heart signal representative of the action of said heart; and a controller, connected to receive said heart signal and to said respirator, for monitoring said heart signal and for generating said control signal when said heart signal is representative of the diastolic phase of said heart, whereby blood being pumped from the heart is assisted by the inspiration pulses generated by said ventilator.
Claim 10
Independent Claim 111 words
A system for maximizing the volume of blood pumped by a heart or optimizing ventilation/perfusion matching in the lungs, said system comprising: a programmable respirator for ventilating lungs associated with said heart, wherein said respirator causes inspiration in response to a control signal, a monitor for generating a heart signal representative of the action of said heart; and a controller, connected to receive said heart signal and to said respirator, for monitoring said heart signal and for generating said control signal when said heart signal is representative of the diastolic phase of said heart, whereby blood being pumped from the heart is assisted by the inspiration pulses generated by said ventilator.
Claim 11
Independent Claim 120 words
A method for maximizing the volume of blood pumped by the heart of a patient or optimizing ventilation/perfusion matching in the lungs of a patient, said method comprising the steps of: ventilating said patient, wherein said ventilation is achieved in response to a control signal; generating a heart signal representative of the action of said heart; generating a flow rate signal representative of the flow rate of air into and out of said lungs; generating a pressure signal representative of the air pressure in said lungs; and generating said control signal in response to said heart signal, said flow rate signal and said pressure signal, whereby the pumping action of said heart is assisted by the ventilation of said lungs.
Claim 12
Independent Claim 120 words
A method for maximizing the volume of blood pumped by the heart of a patient or optimizing ventilation/perfusion matching in the lungs of a patient, said method comprising the steps of: ventilating said patient, wherein said ventilation is achieved in response to a control signal; generating a heart signal representative of the action of said heart; generating a flow rate signal representative of the flow rate of air into and out of said lungs; generating a pressure signal representative of the air pressure in said lungs; and generating said control signal in response to said heart signal, said flow rate signal and said pressure signal, whereby the pumping action of said heart is assisted by the ventilation of said lungs.
Claim 13
Dependent Claim 37 words
The method of claim 9, wherein said step of generating a control signal comprises the steps of monitoring said heart signal, said flow rate signal and said pressure signal and detecting when such signals exceed threshold levels.
Claim 14
Dependent Claim 29 words
The method of claim 10, wherein said step of generating a heart signal comprises the step of generating an electrocardiogram signal, whereby said heart signal comprises an electrocardiogram signal.
Claim 15
Dependent Claim 62 words
The method of claim 11, wherein said heart comprises a ventricle and wherein said step of generating an electrocardiogram signal comprises the step of generating a signal representative of the contraction of said ventricle, said threshold level representative of a point during said ventricular contraction, so that said step of monitoring comprises the step of detecting a particular point during ventricular contraction.
Claim 16
Dependent Claim 35 words
The method of claim 12, wherein said step of detecting a particular point during ventricular contraction comprises the steps of generating a variable reference signal and comparing said electrocardiogram signal to said variable reference signal.
Claim 17
Dependent Claim 14 words
The method of claim 10, further comprising the step of delaying said control signal.
Claim 18
Dependent Claim 32 words
The method of claim 14, wherein the step of delaying said control signal comprises the step of delaying said control signal until said heart is in the diastolic portion of its cycle.
Claim 19
Independent Claim 118 words
A method for treating respiratory, cardiac or coextensive respiratory and cardiac failure, wherein heart and lungs are functioning abnormally, said method comprising the steps of: providing a respirator for ventilating said lungs, wherein said respirator is operative in response to a control signal; generating a heart signal representative of the action of said heart; generating a flow rate signal representative of the flow rate of air into and out of said lungs; generating a pressure signal representative of the air pressure in said lungs; and generating said control signal in response to said heart signal, said flow rate signal and said pressure signal, whereby the pumping action of said heart is assisted by the ventilation of said lungs.
Claim 20
Independent Claim 118 words
A method for treating respiratory, cardiac or coextensive respiratory and cardiac failure, wherein heart and lungs are functioning abnormally, said method comprising the steps of: providing a respirator for ventilating said lungs, wherein said respirator is operative in response to a control signal; generating a heart signal representative of the action of said heart; generating a flow rate signal representative of the flow rate of air into and out of said lungs; generating a pressure signal representative of the air pressure in said lungs; and generating said control signal in response to said heart signal, said flow rate signal and said pressure signal, whereby the pumping action of said heart is assisted by the ventilation of said lungs.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-02-23 1996-08-24 1997-02-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-02-23 2000-08-24 2001-02-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-02-23 2004-08-24 2005-02-23 $7700.00 Window Closed / Lapsed

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