US5169930A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fibronectin receptor
Assignee: Sanford Burnham Prebys Medical Discovery Institute
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Filing: 1990-01-05
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Granted: 1992-12-08
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Expires: 2010-01-05
Abstract
Abstract The present invention provides a substantially pure integrin-type receptor characterized in that it consists of an α v and a β 1 subunit. The α v β 1 integrin binds to fibronectin and GRGDSPK but does not bind to vitronectin. The α v β 1 integrin can be used to determine the presence of a α v β 1 ligand and to develop adhesion peptides specific for the various integrins. The presence of the α v β 1 integrin can be used to assess ability of cells to adhere to fibronectin.
Inventors
- 👤 Erkki I. Ruoslahti
- 👤 Guido Tarone
- 👤 Filippo G. Giancotti
- 👤 Bruce E. Vogel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 03:21
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/705; C07K14/70546; C07K14/7055; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
27 words
A substantially pure active integrin comprising subunits α V and β 1 or their immunological equivalents, wherein said integrin binds to GRGDSPK in a cell adhesion assay.
Claim 2
Dependent Claim
27 words
A substantially pure active integrin comprising subunits α V and β 1 or their immunological equivalents, wherein said integrin binds to GRGDSPK in a cell adhesion assay.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-12-08 | 1996-06-08 | 1996-12-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-12-08 | 2000-06-08 | 2000-12-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-12-08 | 2004-06-08 | 2004-12-08 | $7700.00 | Window Closed / Lapsed |