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US5167649A Expired / Lapsed US ⏱️ 0.0 years remaining

Drug delivery system for the removal of dermal lesions

Assignee: Individual
•
Filing: 1992-04-17
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Granted: 1992-12-01
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Expires: 2012-04-17
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Abstract

Abstract A drug delivery system for the removal of dermal lesions which includes a pad of viscoelastic rubber and oil gel, perfused with a pharmacologically active substance, which is partially encapsulated between a first layer of oil and water impermeable material and a second layer of oil and water impermeable material. The second layer includes an aperture, corresponding to the dimension of the dermal lesion, which is smaller than, and located within, the periphery of the adjacent medicated viscoelastic rubber and oil gel pad. The two layers of oil and water impermeable material are bonded together to form a seal about the periphery of the viscoelastic rubber and oil gel pad. The surface of the patch which is affixed to a wearer's skin is provided with a pressure sensitive adhesive. The viscoelastic rubber and oil pad and the encapsulating layers preferably are transparent.

Inventors

  • 👤 Gerald P. Zook

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 20:56
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61F; A61F13/00; A61F13/02; A61F13/0203; A61K9/7084; A61F2013/00361; A61F2013/00365; A61F2013/00506; A61F2013/00846; A61F2013/00855; A61F2013/00885; A61F2013/00893; A61F2013/00902; A61F2013/00906

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 240 words
A drug delivery system, in the form of a patch, having a surface affixed to a wearer's skin, for the removal of dermal lesions, comprising: a. a viscoelastic rubber and oil gel pad, having a first surface, an opposing second surface, and a periphery, said viscoelastic rubber and oil gel pad being perfused with a pharmacologically active substance; b. a first layer of oil and water impermeable material, covering said first surface of said viscoelastic rubber and oil gel pad; and c. a second layer of oil and water impermeable material, having an aperture formed therein of less dimension than said second surface of said viscoelastic rubber and oil gel pad; said second layer of oil and water impermeable material, except for said aperture, covering said second surface of said viscoelastic rubber and oil gel pad; said aperture being positioned upon said second surface, and within said periphery, of said viscoelastic rubber and oil gel pad; d. said first and second layers of oil and water impermeable material being joined to form a seal about the periphery of said viscoelasic rubber and oil gel pad, so as to encapsulate said viscoelastic rubber and oil gel pad except for said aperture; e. wherein a portion of said second surface of said viscoelastic rubber and oil gel pad is exposed through said aperture and is held in direct contact with a dermal lesion when said patch is applied to a wearer's skin.
Claim 2
Dependent Claim 240 words
A drug delivery system, in the form of a patch, having a surface affixed to a wearer's skin, for the removal of dermal lesions, comprising: a. a viscoelastic rubber and oil gel pad, having a first surface, an opposing second surface, and a periphery, said viscoelastic rubber and oil gel pad being perfused with a pharmacologically active substance; b. a first layer of oil and water impermeable material, covering said first surface of said viscoelastic rubber and oil gel pad; and c. a second layer of oil and water impermeable material, having an aperture formed therein of less dimension than said second surface of said viscoelastic rubber and oil gel pad; said second layer of oil and water impermeable material, except for said aperture, covering said second surface of said viscoelastic rubber and oil gel pad; said aperture being positioned upon said second surface, and within said periphery, of said viscoelastic rubber and oil gel pad; d. said first and second layers of oil and water impermeable material being joined to form a seal about the periphery of said viscoelasic rubber and oil gel pad, so as to encapsulate said viscoelastic rubber and oil gel pad except for said aperture; e. wherein a portion of said second surface of said viscoelastic rubber and oil gel pad is exposed through said aperture and is held in direct contact with a dermal lesion when said patch is applied to a wearer's skin.
Claim 3
Dependent Claim 39 words
The drug delivery system for the removal of dermal lesions, as recited in claim 1, wherein said first and second layers of oil and water impermeable material and said viscoelastic rubber and oil gel pad all are substantially transparent.
Claim 4
Dependent Claim 39 words
The drug delivery system for the removal of dermal lesions, as recited in claim 1, wherein said pharmacologically active substance includes one or more agents from the following group: cantharidin, podophyllin, salicylic acid, lactic acid, trichloracetic acid, and 5-fluorouracil.
Claim 5
Dependent Claim 31 words
The drug delivery system for the removal of dermal lesions, as recited in claim 1, wherein the rubber of said viscoelastic rubber and oil gel is a triblock copolymer of styrene-ethylene-butylene-styrene.
Claim 6
Dependent Claim 29 words
The drug delivery system for the removal of dermal lesions, as recited in claim 1, wherein the oil of said viscoelastic rubber and oil gel is Mineral Oil, U.S.P.
Claim 7
Dependent Claim 34 words
The drug delivery system for the removal of dermal lesions, as recited in claim 1, wherein, additionally, a means of affixing the surface of the patch to the wearer's skin includes pressure sensitive adhesive.

References Cited (Backward Citations)

US3419006A Cited
US4158359A Cited
US4991574A Cited
US4842931A Cited
US4988341A Cited
US5098421A Cited
US5106629A Cited
US5108710A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-12-01 1996-06-01 1996-12-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-12-01 2000-06-01 2000-12-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-12-01 2004-06-01 2004-12-01 $7700.00 Window Closed / Lapsed

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