US5158573A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Injectable polymeric bodies
Assignee: WPAMS ACQUISITION CORP
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Filing: 1991-03-22
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Granted: 1992-10-27
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Expires: 2011-03-22
Abstract
Abstract An injectable composition consisting of a plurality of discrete physiologically-compatible, non-biodegradable, silicone rubber bodies, said bodies having (i) a maximum outside dimension of from about 0.005 to 0.08 inch (125 to 2000μ), (ii) reversible deformability of about 20 to 75% of their unstressed outside dimension and (iii) a lubricious surface, wherein the lubricious surface is provided by a thin film coating of a liquid lubricant; and a method for treating a tissue condition in a patient using said composition.
Inventors
- 👤 Eric P. Berg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:17
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/52; A61F; A61F2/00; A61F2/0059; A61L27/14; A61L27/16; A61L27/26; Y; Y10; Y10S; Y10S623/00; Y10S623/924; Y10S623/926
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
65 words
An injectable composition consisting of a plurality of discrete physiologically-compatible, non-biodegradable, silicone rubber bodies, said bodies having (i) a maximum outside dimension of from about 0.005 to 0.08 inch (125 to 2000μ), (ii) reversible deformability of about 20 to 75% of their unstressed outside dimension, and (iii) a lubricious surface, wherein the lubricious surface is provided by a thin film coating of a liquid lubricant.
Claim 2
Dependent Claim
65 words
An injectable composition consisting of a plurality of discrete physiologically-compatible, non-biodegradable, silicone rubber bodies, said bodies having (i) a maximum outside dimension of from about 0.005 to 0.08 inch (125 to 2000μ), (ii) reversible deformability of about 20 to 75% of their unstressed outside dimension, and (iii) a lubricious surface, wherein the lubricious surface is provided by a thin film coating of a liquid lubricant.
Claim 3
Dependent Claim
27 words
A composition according to claim 1, in which said silicone rubber bodies have a maximum outside dimension of from about 0.007 to 0.045 inch (175 to 1125μ).
Claim 4
Dependent Claim
29 words
A composition according to claim 2, in which said liquid lubricant is a solution of 25% polyvinyl pyrrolidone having a molecular weight of about 360,000 in phosphate buffered saline.
Claim 5
Dependent Claim
58 words
A composition according to claim 1, in which said liquid lubricant is selected from the group consisting of (i) a solution of polyvinyl pyrrolidine in glycerol or phosphate buffered saline; (ii) a solution of hyaluronic acid in a glycerol/water mixture or phosphate buffered saline; and (iii) a solution of a water-soluble polysaccharide in glycerol or phosphate buffered saline.
Claim 6
Dependent Claim
27 words
A composition according to claim 4, in which said liquid lubricant is a solution of 5% polyvinyl pyrrolidone having a molecular weight of about 360,000 in glycerol.
Claim 7
Dependent Claim
28 words
A composition according to claim 4, in which said liquid lubricant is a solution of 0.2% hyaluronic acid having a molecular weight of about 600,000 in 90:10 glycerol/water.
Claim 8
Dependent Claim
22 words
A composition according to claim 4, in which said liquid lubricant is a solution of 2.0% hyaluronic acid in phophate buffered saline.
Claim 9
Dependent Claim
19 words
A composition according to claim 4, in which said liquid lubricant is a solution of 10% dextran in glycerol.
Claim 10
Dependent Claim
21 words
A composition according to claim 4, in which said liquid lubricant is a solution of 50% dextran in phosphate buffered saline.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-10-27 | 1996-04-27 | 1996-10-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-10-27 | 2000-04-27 | 2000-10-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-10-27 | 2004-04-27 | 2004-10-27 | $7700.00 | Window Closed / Lapsed |