US5156148A
Expired / Lapsed
US
⏱️ 0.0 years remaining
System for treating a malfunctioning heart
Assignee: Medtronic Inc
•
Filing: 1991-05-13
•
Granted: 1992-10-20
•
Expires: 2011-05-13
Abstract
Abstract A system for treating the malfunctioning heart of a patient includes means which derive at least one electrical signal from the patient's heart and means which derive at least one physiologic signal from or related to the patient's circulatory system. A central processing unit, which may be a programmable microprocessor, with a RAM and a ROM, receives and responds to the at least one electrical signal and to the at least one physiologic signal. Output means, which may include a heart assist pump, pacers, drug delivery devices and cardioverting/defibrillating apparatuses, controlled by the central processing unit provides corrective measure(s) to the patient. Adjustable or variable baselines, against which a representation of the current, short-term magnitude of the selected physiologic parameter or parameters are provided. The variable baseline(s) is (are) a representation of the selected physiologic parameter(s) determined over a long term of greater duration than the short term over which the current magnitude(s) of the parameter(s) is (are) measured.
Inventors
- 👤 Todd J. Cohen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 15:54
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/38; A61N1/39; A61N1/3918; A61N1/36; A61N1/362; A61N1/365; A61N1/36514; A61N1/36564; A61N1/3956; A61N1/3962; A61N1/39622
Claims Analysis
Total Claims: 107
Claim 1
Independent Claim
126 words
In an implantable system for treating the malfunctioning heart of a patient, the combination of means for deriving at least one electrical signal from the patient's heart, means for deriving at least one physiologic signal from or related to the patient's circulatory system, a central processing unit for controlling delivery of selected heart-malfunction-corrective inputs to the patient, means for inputting the at least one electrical signal and the at least one physiologic signal to the central processing unit, and output means responsive to output signals form the central processing unit, including cardioverting/defibrillating means, for providing under control of the central processing unit at least one heart-malfunction-corrective input to the patient from among a plurality of the heart-malfunction-corrective inputs, whereby malfunctions of the heart may be corrected.
Claim 2
Dependent Claim
126 words
In an implantable system for treating the malfunctioning heart of a patient, the combination of means for deriving at least one electrical signal from the patient's heart, means for deriving at least one physiologic signal from or related to the patient's circulatory system, a central processing unit for controlling delivery of selected heart-malfunction-corrective inputs to the patient, means for inputting the at least one electrical signal and the at least one physiologic signal to the central processing unit, and output means responsive to output signals form the central processing unit, including cardioverting/defibrillating means, for providing under control of the central processing unit at least one heart-malfunction-corrective input to the patient from among a plurality of the heart-malfunction-corrective inputs, whereby malfunctions of the heart may be corrected.
Claim 3
Dependent Claim
20 words
The implantable system of claim 1, wherein the output means includes antitachycardia pacing means controlled by the central processing unit.
Claim 4
Dependent Claim
20 words
The implantable system of claim 1, wherein the output means includes antibradycardia pacing means controlled by the central processing unit.
Claim 5
Dependent Claim
13 words
The implantable system of claim 1, wherein the central processing unit is programmable.
Claim 6
Dependent Claim
20 words
The implantable system of claim 1, wherein the output means includes drug delivery means controlled by the central processing unit.
Claim 7
Dependent Claim
20 words
The implantable system of claim 1, wherein the output means includes a heart-assist device controlled by the central processing unit.
Claim 8
Dependent Claim
34 words
The implantable system of claim 1, further including monitoring means and/or recording means coupled to the central processing unit for monitoring and/or recording input and output signals to and from the central processing unit.
Claim 9
Dependent Claim
28 words
The implantable system of claim 1, wherein the output means further includes drug delivery means, antitachycardia pacing means and antibradycardia pacing means controlled by the central processing unit.
Claim 10
Dependent Claim
25 words
The implantable system of claim 1, wherein the output means further include antitachycardia pacing means and antibradycardia pacing means controlled by the central processing unit.
Claim 11
Dependent Claim
21 words
The implantable system of claim 1, wherein the output means further includes antibradycardia pacing means controlled by the central processing unit.
Claim 12
Dependent Claim
43 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable supraventricular tachycardia.
Claim 13
Dependent Claim
22 words
The implantable system of claim 11, which includes means for supplying therapy to the patient whereby stable supraventricular tachycardia may be overcome.
Claim 14
Dependent Claim
43 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable supraventricular tachycardia.
Claim 15
Dependent Claim
22 words
The implantable system of claim 13, which includes means for supplying therapy to the patient whereby unstable supraventricular tachycardia may be overcome.
Claim 16
Dependent Claim
43 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable ventricular tachycardia.
Claim 17
Dependent Claim
22 words
The implantable system of claim 15, which includes means for supplying therapy to the patient whereby stable ventricular tachycardia may be overcome.
Claim 18
Dependent Claim
43 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable ventricular tachycardia.
Claim 19
Dependent Claim
22 words
The implantable system of claim 17, which includes means for supplying therapy to the patient whereby unstable ventricular tachycardia may be overcome.
Claim 20
Dependent Claim
38 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsible to the at least one electrical signal for identifying rapid ventricular tachycardia and ventricular fibrillation.
Claim 21
Dependent Claim
25 words
The implantable system of claim 19, which includes means for supplying therapy to the patient whereby rapid ventricular tachycardia and ventricular fibrillation may be overcome.
Claim 22
Dependent Claim
42 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to at least one electrical signal and to the at least one physiologic signal for identifying rapid ventricular fibrillation.
Claim 23
Dependent Claim
22 words
The implantable system of claim 21, which includes means for supplying therapy to the patient whereby rapid ventricular fibrillation may be overcome.
Claim 24
Dependent Claim
41 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying asystole.
Claim 25
Dependent Claim
20 words
The implantable system of claim 23, which includes means for supplying therapy to the patient whereby asystole may be overcome.
Claim 26
Dependent Claim
42 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable bradycardia.
Claim 27
Dependent Claim
21 words
The implantable system of claim 25, which includes means for supplying therapy to the patient whereby stable bradycardia may be overcome.
Claim 28
Dependent Claim
42 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable bradycardia.
Claim 29
Dependent Claim
21 words
The implantable system of claim 27, which includes means for supplying therapy to the patient whereby unstable bradycardia may be overcome.
Claim 30
Dependent Claim
41 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying ischemia.
Claim 31
Dependent Claim
20 words
The implantable system of claim 29, which includes means for supplying therapy to the patient whereby ischemia may be overcome.
Claim 32
Dependent Claim
42 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying early infarction.
Claim 33
Dependent Claim
21 words
The implantable system of claim 31, which includes means for supplying therapy to the patient whereby early infarction may be overcome.
Claim 34
Dependent Claim
43 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying heart failure alone.
Claim 35
Dependent Claim
22 words
The implantable system of claim 33, which includes means for supplying therapy to the patient whereby heart failure alone may be overcome.
Claim 36
Dependent Claim
72 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable supraventricular tachycardia, unstable supraventricular tachycardia, stable ventricular tachycardia, unstable ventricular tachycardia, stable atrial fibrillation, unstable atrial fibrillation, ventricular fibrillation, asystole, stable bradycardia, unstable bradycardia, ischemia, early infarction and heart failure alone.
Claim 37
Dependent Claim
66 words
The implantable system of claim 1, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable supraventricular tachycardia, unstable supraventricular tachycardia, stable ventricular tachycardia, unstable ventricular tachycardia, stable atrial fibrillation, unstable atrial fibrillation, ventricular fibrillation, asystole, stable bradycardia, and unstable bradycardia.
Claim 38
Dependent Claim
49 words
The implantable system of claim 1, including means coupled to said means for deriving at least one physiologic signal and responsive thereto for determining a change in a given physiologic parameter of at least a predetermined magnitude from a baseline for the parameter as represented by the physiologic signal.
Claim 39
Dependent Claim
89 words
The implantable system according to claim 1, including means coupled to said means for deriving at least one physiologic signal and responsive thereto over a period of given duration for establishing a varying baseline for a given physiologic parameter as represented by the physiologic signal, and means coupled to said means for deriving at least one physiologic signal and responsive thereto for determining current level of the parameter as represented by the physiologic signal over a period of predetermined duration which is shorter than the period of given duration.
Claim 40
Dependent Claim
25 words
The implantable system according to claim 1, including means for adjustably setting a baseline for a given physiologic parameter as represented by the physiologic signal.
Claim 41
Dependent Claim
144 words
In a system for treating the malfunctioning heart of a patient, a combination of means for deriving at least one electrical signal from the patient's heart, means for deriving at least one physiologic signal from or related to the patient's circulatory system, means responsive to the physiologic signal for determining a change in a physiologic parameter of at least a predetermined magnitude from a baseline for the parameter, a central processing unit, means for inputting the at least one electrical signal and the at least one physiologic signal to the central processing unit, and output means coupled to the central processing unit and responsive to output signals therefor, including cardioverting/defibrillating means, for providing under control of the central processing unit at least one heart-malfunction-corrective input to the patient from among a plurality of the heart-malfunction-corrective inputs, whereby malfunctions of the heart may be corrected.
Claim 42
Dependent Claim
144 words
In a system for treating the malfunctioning heart of a patient, a combination of means for deriving at least one electrical signal from the patient's heart, means for deriving at least one physiologic signal from or related to the patient's circulatory system, means responsive to the physiologic signal for determining a change in a physiologic parameter of at least a predetermined magnitude from a baseline for the parameter, a central processing unit, means for inputting the at least one electrical signal and the at least one physiologic signal to the central processing unit, and output means coupled to the central processing unit and responsive to output signals therefor, including cardioverting/defibrillating means, for providing under control of the central processing unit at least one heart-malfunction-corrective input to the patient from among a plurality of the heart-malfunction-corrective inputs, whereby malfunctions of the heart may be corrected.
Claim 43
Dependent Claim
42 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable supraventricular tachycardia.
Claim 44
Dependent Claim
21 words
The system of claim 41, which includes means for supplying therapy to the patient whereby stable supraventricular tachycardia may be overcome.
Claim 45
Dependent Claim
42 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable supraventricular tachycardia.
Claim 46
Dependent Claim
21 words
The system of claim 43, which includes means for supplying therapy to the patient whereby unstable supraventricular tachycardia may be overcome.
Claim 47
Dependent Claim
42 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable ventricular tachycardia.
Claim 48
Dependent Claim
21 words
The system of claim 45, which includes means for supplying therapy to the patient whereby stable ventricular tachycardia may be overcome.
Claim 49
Dependent Claim
42 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable ventricular tachycardia.
Claim 50
Dependent Claim
21 words
The system of claim 47, which includes means for supplying therapy to the patient whereby unstable ventricular tachycardia may be overcome.
Claim 51
Dependent Claim
37 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsible to the at least one electrical signal for identifying rapid ventricular tachycardia and ventricular fibrillation.
Claim 52
Dependent Claim
24 words
The system of claim 49, which includes means for supplying therapy to the patient whereby rapid ventricular tachycardia and ventricular fibrillation may be overcome.
Claim 53
Dependent Claim
41 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to at least one electrical signal and to the at least one physiologic signal for identifying rapid ventricular fibrillation.
Claim 54
Dependent Claim
21 words
The system of claim 51, which includes means for supplying therapy to the patient whereby rapid ventricular fibrillation may be overcome.
Claim 55
Dependent Claim
40 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying asystole.
Claim 56
Dependent Claim
19 words
The system of claim 53, which includes means for supplying therapy to the patient whereby asystole may be overcome.
Claim 57
Dependent Claim
41 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable bradycardia.
Claim 58
Dependent Claim
20 words
The system of claim 55, which includes means for supplying therapy to the patient whereby stable bradycardia may be overcome.
Claim 59
Dependent Claim
41 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable bradycardia.
Claim 60
Dependent Claim
20 words
The system of claim 57, which includes means for supplying therapy to the patient whereby unstable bradycardia may be overcome.
Claim 61
Dependent Claim
40 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying ischemia.
Claim 62
Dependent Claim
19 words
The system of claim 59, which includes means for supplying therapy to the patient whereby ischemia may be overcome.
Claim 63
Dependent Claim
41 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying early infarction.
Claim 64
Dependent Claim
20 words
The system of claim 61, which includes means for supplying therapy to the patient whereby early infarction may be overcome.
Claim 65
Dependent Claim
42 words
The system of claim 40, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying heart failure alone.
Claim 66
Dependent Claim
21 words
The system of claim 63, which includes means for supplying therapy to the patient whereby heart failure alone may be overcome.
Claim 67
Dependent Claim
56 words
The combination according to claim 40, including means responsive to the physiologic signal over a period of given duration for establishing a varying baseline for the parameter, and means responsive to the physiologic signal for determining current level of the parameter over a period of predetermined duration which is shorter than said period of given duration.
Claim 68
Dependent Claim
17 words
The combination according to claim 40, including means for adjustably setting the baseline for the physiologic parameter.
Claim 69
Dependent Claim
15 words
The system according to claim 40, which is adapted to be implanted in a patient.
Claim 70
Dependent Claim
43 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable supraventricular tachycardia.
Claim 71
Dependent Claim
22 words
The implantable system of claim 68, which includes means for supplying therapy to the patient whereby stable supraventricular tachycardia may be overcome.
Claim 72
Dependent Claim
43 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable supraventricular tachycardia.
Claim 73
Dependent Claim
22 words
The implantable system of claim 70, which includes means for supplying therapy to the patient whereby unstable supraventricular tachycardia may be overcome.
Claim 74
Dependent Claim
43 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable ventricular tachycardia.
Claim 75
Dependent Claim
22 words
The implantable system of claim 22, which includes means for supplying therapy to the patient whereby stable ventricular tachycardia may be overcome.
Claim 76
Dependent Claim
43 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable ventricular tachycardia.
Claim 77
Dependent Claim
22 words
The implantable system of claim 74, which includes means for supplying therapy to the patient whereby unstable ventricular tachycardia may be overcome.
Claim 78
Dependent Claim
38 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsible to the at least one electrical signal for identifying rapid ventricular tachycardia and ventricular fibrillation.
Claim 79
Dependent Claim
25 words
The implantable system of claim 76, which includes means for supplying therapy to the patient whereby rapid ventricular tachycardia and ventricular fibrillation may be overcome.
Claim 80
Dependent Claim
42 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to at least one electrical signal and to the at least one physiologic signal for identifying rapid ventricular fibrillation.
Claim 81
Dependent Claim
22 words
The implantable system of claim 78, which includes means for supplying therapy to the patient whereby rapid ventricular fibrillation may be overcome.
Claim 82
Dependent Claim
41 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying asystole.
Claim 83
Dependent Claim
20 words
The implantable system of claim 80, which includes means for supplying therapy to the patient whereby asystole may be overcome.
Claim 84
Dependent Claim
42 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying stable bradycardia.
Claim 85
Dependent Claim
21 words
The implantable system of claim 82, which includes means for supplying therapy to the patient whereby stable bradycardia may be overcome.
Claim 86
Dependent Claim
42 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying unstable bradycardia.
Claim 87
Dependent Claim
21 words
The implantable system of claim 84, which includes means for supplying therapy to the patient whereby unstable bradycardia may be overcome.
Claim 88
Dependent Claim
41 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying ischemia.
Claim 89
Dependent Claim
20 words
The implantable system of claim 86, which includes means for supplying therapy to the patient whereby ischemia may be overcome.
Claim 90
Dependent Claim
42 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying early infarction.
Claim 91
Dependent Claim
21 words
The implantable system of claim 88, which includes means for supplying therapy to the patient whereby early infarction may be overcome.
Claim 92
Dependent Claim
43 words
The implantable system of claim 67, including means for monitoring heart rhythm to develop the at least one electrical signal, and means responsive to the at least one electrical signal and to the at least one physiologic signal for identifying heart failure alone.
Claim 93
Dependent Claim
22 words
The implantable system of claim 90, which includes means for supplying therapy to the patient whereby heart failure alone may be overcome.
Claim 94
Dependent Claim
56 words
The combination according to claim 67, including means responsive to the physiologic signal over a period of given duration for establishing a varying baseline for the parameter, and means responsive to the physiologic signal for determining current level of the parameter over a period of predetermined duration which is shorter than said period of given duration.
Claim 95
Dependent Claim
17 words
The combination according to claim 67, including means for adjustably setting the baseline for the physiologic parameter.
Claim 96
Dependent Claim
196 words
Apparatus for treating a malfunctioning heart of a patient by supplying cardioverting/defibrillating energy to the patient to overcome or avoid hemodynamic comprise and avoid consequent death of the patient who may be exhibiting sudden death syndrome, comprising computerized means having at least a first input and a second input, and at least one output, means for obtaining an electrical signal from the patient's heart and for feeding that electrical signal to the first input of the computerized means, means for monitoring at least one selected parameter of the patient's circulatory system to develop a physiologic signal representation thereof, means for feeding the physiologic signal to the second input, means within the computer means for establishing a baseline for the selected parameter of the patient to develop a baseline signal representation thereof, comparison means within said computerized means for comparing the baseline signal on a short term basis with the physiological signal, cardioverting/defibrillating means for delivering cardioverting/defibrillating energy to the patient, and means coupled to and responsive to the output from the computerized means for triggering the cardioverting/defibrillating means to thereby provide cardioverting/defibrillating energy to the patient's heart to avoid or overcome hemodynamic comprise of the patient.
Claim 97
Dependent Claim
196 words
Apparatus for treating a malfunctioning heart of a patient by supplying cardioverting/defibrillating energy to the patient to overcome or avoid hemodynamic comprise and avoid consequent death of the patient who may be exhibiting sudden death syndrome, comprising computerized means having at least a first input and a second input, and at least one output, means for obtaining an electrical signal from the patient's heart and for feeding that electrical signal to the first input of the computerized means, means for monitoring at least one selected parameter of the patient's circulatory system to develop a physiologic signal representation thereof, means for feeding the physiologic signal to the second input, means within the computer means for establishing a baseline for the selected parameter of the patient to develop a baseline signal representation thereof, comparison means within said computerized means for comparing the baseline signal on a short term basis with the physiological signal, cardioverting/defibrillating means for delivering cardioverting/defibrillating energy to the patient, and means coupled to and responsive to the output from the computerized means for triggering the cardioverting/defibrillating means to thereby provide cardioverting/defibrillating energy to the patient's heart to avoid or overcome hemodynamic comprise of the patient.
Claim 98
Dependent Claim
13 words
The apparatus of claim 94, wherein the computerized means comprises a programmable microprocessor.
Claim 99
Dependent Claim
25 words
The apparatus of claim 94, wherein the means for monitoring at least one selected parameter comprises means for monitoring pressure in the patient's circulatory system.
Claim 100
Dependent Claim
28 words
The apparatus of claim 94, wherein the means for monitoring at least one selected parameter comprises means for monitoring pressure in the right atrium of the patient's heart.
Claim 101
Dependent Claim
16 words
The apparatus of claim 94, wherein the selected parameter is oxygen saturation in mixed venous blood.
Claim 102
Dependent Claim
17 words
The apparatus of claim 94, wherein the selected parameter is potassium ion level in the patient's blood.
Claim 103
Dependent Claim
16 words
The apparatus of claim 94, wherein the selected parameter is lactic acid in the patient's blood.
Claim 104
Dependent Claim
24 words
The apparatus of claim 94, wherein the means for establishing a baseline comprises means for establishing a long-term variable baseline of the selected parameter.
Claim 105
Dependent Claim
24 words
The apparatus of claim 94, wherein the apparatus is an implantable apparatus which is adapted to be implanted in its entirety into the patient.
Claim 106
Dependent Claim
19 words
The apparatus of claim 94, wherein the apparatus is adapted to be at least partially external to the patient.
Claim 107
Dependent Claim
35 words
The apparatus of claim 94, further including antibradycardia pacing means, antitachycardia pacing means and drug delivery devices, and means for selectively energizing the antibradycardia pacing means, the antitachycardia pacing means and the drug delivery devices.
References Cited (Backward Citations)
US3614955A
Cited
US3878564A
Cited
US3866615A
Cited
US4807629A
Cited
US4799493A
Cited
US4774950A
Cited
US4819662A
Cited
US4869252A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-10-20 | 1996-04-20 | 1996-10-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-10-20 | 2000-04-20 | 2000-10-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-10-20 | 2004-04-20 | 2004-10-20 | $7700.00 | Window Closed / Lapsed |