US5155435A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for performing interventional medical procedures using MR imaging of interventional device superimposed with ghost patient image
Assignee: University of California
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Filing: 1991-08-08
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Granted: 1992-10-13
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Expires: 2011-08-08
Abstract
Abstract Positioning of interventional devices within the patient image volume of an MRI system is performed while viewing real-time fluoroscopic MR images of such devices superimposed upon a saved prior image ("ghost") of patient anatomy that was earlier located within the same image volume. After such interventional medical procedure is thoroughly planned using the earlier acquired three-dimensional ghost image, the patient anatomy is relocated within the image volume and the final selected trajectory for the interventional device or medical procedure is then performed (preferably while real time MRI fluoroscopy is used to monitor the actual interventional procedure within the real patient anatomy).
Inventors
- 👤 Leon Kaufman
- 👤 David M. Kramer
- 👤 Christine Hawryszko
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:57
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/28; A; A61; A61B; A61B90/00; A61B90/36; A61B90/37; A61B2090/374; A61B34/00; A61B34/10; A61B90/10
Claims Analysis
Total Claims: 40
Claim 1
Independent Claim
44 words
An MRI method comprising: positioning an interventional device within the patient image volume of an MRI system while viewing real-time fluoroscopic MR images of such device superimposed on a saved prior image of patient anatomy that was earlier located within the same image volume.
Claim 2
Dependent Claim
44 words
An MRI method comprising: positioning an interventional device within the patient image volume of an MRI system while viewing real-time fluoroscopic MR images of such device superimposed on a saved prior image of patient anatomy that was earlier located within the same image volume.
Claim 3
Dependent Claim
68 words
An MRI method as in claim 1 further comprising: defining a repeatable trajectory to at least one predetermined position of the interventional device within the image volume; locating patient anatomy within the image volume to correspond with that of the saved prior image; and re-introducing said interventional device into the image volume and into the patient anatomy along said repeatable trajectory to said at least one predetermined position.
Claim 4
Dependent Claim
28 words
An MRI method as in claim 2 wherein during said re-introducing step, the movement of said interventional device within the patient anatomy is subjected to real-time fluoroscopic MRI.
Claim 5
Dependent Claim
24 words
An MRI method comprising: superimposing a prior saved image of a first physical field with real-time fluoroscopic MR images of a second physical field.
Claim 6
Dependent Claim
24 words
An MRI method comprising: superimposing a prior saved image of a first physical field with real-time fluoroscopic MR images of a second physical field.
Claim 7
Dependent Claim
25 words
An MRI method as in claim 4 wherein said first physical field comprises a patient anatomy and said second physical field comprises an interventional device.
Claim 8
Dependent Claim
25 words
An MRI method as in claim 4 wherein said first physical field comprises an interventional device and said second physical field comprises a patient anatomy.
Claim 9
Dependent Claim
32 words
An MRI method as in claim 4, 5 or 6 further comprising: thereafter generating real-time fluoroscopic MR images of said first physical field as it physically merges with said second physical field.
Claim 10
Dependent Claim
135 words
An MRI method for facilitating the safe introduction of interventional devices into patient anatomy, said method comprising: placing patient anatomy within the image volume of an MRI system; creating and saving an MR image of said patient anatomy; removing said patient anatomy from the image volume; locating a desired trajectory for an interventional device within said image volume while superimposing the saved MR image of said patient anatomy with real-time fluoroscopic MR images of the interventional device; removing said interventional device from the MR image of the patient anatomy while retaining an ability to retrace said desired trajectory; returning said patient anatomy to the image volume in substantial registry with its earlier position at the time the saved MR image was created; and introducing said interventional device into said patient anatomy along said desired trajectory.
Claim 11
Dependent Claim
135 words
An MRI method for facilitating the safe introduction of interventional devices into patient anatomy, said method comprising: placing patient anatomy within the image volume of an MRI system; creating and saving an MR image of said patient anatomy; removing said patient anatomy from the image volume; locating a desired trajectory for an interventional device within said image volume while superimposing the saved MR image of said patient anatomy with real-time fluoroscopic MR images of the interventional device; removing said interventional device from the MR image of the patient anatomy while retaining an ability to retrace said desired trajectory; returning said patient anatomy to the image volume in substantial registry with its earlier position at the time the saved MR image was created; and introducing said interventional device into said patient anatomy along said desired trajectory.
Claim 12
Dependent Claim
37 words
An MRI method as in claim 8 wherein, during said introducing step, MRI fluoroscopy is utilized to provide substantially real time images of said patient anatomy and of said interventional device as it retraces said desired trajectory.
Claim 13
Dependent Claim
24 words
An MRI method as in claim 8 wherein, during said locating step, said interventional device is at least partly loaded with an MR-visible fluid.
Claim 14
Dependent Claim
24 words
An MRI method as in claim 8 wherein, during said locating step, said interventional device is at least partly surrounded by an MR-visible fluid.
Claim 15
Dependent Claim
41 words
An MRI method as in claim 8 wherein said interventional device is mounted for movement within an adjustable guiding jig which can be adjusted to at least partially define said desired trajectory and to thereafter facilitate retracing of that same trajectory.
Claim 16
Dependent Claim
27 words
An MRI method as in claim 8 wherein said interventional device is used in a stereotatic procedure coordinated with a stereotatic frame affixed to the patient anatomy.
Claim 17
Dependent Claim
19 words
An MRI method as in claim 8 wherein said interventional device is used to withdraw patient tissue for biopsy.
Claim 18
Dependent Claim
22 words
An MRI method as in claim 8 wherein said interventional device is used to impart treatment to tissues within said patient anatomy.
Claim 19
Dependent Claim
29 words
An MRI method as in claim 8 performed with an MRI system having a main magnet structure which is openly accessible from a lateral side of the patient anatomy.
Claim 20
Dependent Claim
32 words
An MRI method as in claim 8 wherein said returning step includes creating new MR images of the patient anatomy and superimposing same with the earlier saved image of the patient anatomy.
Claim 21
Dependent Claim
48 words
An MRI method as in claim 8 wherein said locating step includes plural trial attempts to locate trajectories for the interventional device reusing the same superimposed saved image of the patient anatomy for each trial and a selection of one such trajectory as the optimum and desired trajectory.
Claim 22
Dependent Claim
66 words
An MRI apparatus comprising: an open structure background MRI magnet allowing lateral access to a patient imaging volume for performance, of interventional procedures; and means for positioning an interventional device within the patient image volume of an MRI system while viewing real-time fluoroscopic MR images of such device superimposed on a saved prior image of patient anatomy that was earlier located within the same image volume.
Claim 23
Dependent Claim
66 words
An MRI apparatus comprising: an open structure background MRI magnet allowing lateral access to a patient imaging volume for performance, of interventional procedures; and means for positioning an interventional device within the patient image volume of an MRI system while viewing real-time fluoroscopic MR images of such device superimposed on a saved prior image of patient anatomy that was earlier located within the same image volume.
Claim 24
Dependent Claim
74 words
An MRI apparatus as in claim 19 further comprising: means for defining a repeatable trajectory to at least one predetermined position of the interventional device within the image volume; means for locating patient anatomy within the image volume to correspond with that of the saved prior image; and means for re-introducing said interventional device into the image volume and into the patient anatomy along said repeatable trajectory to said at least one predetermined position.
Claim 25
Dependent Claim
30 words
An MRI apparatus as in claim 20 including means for performing real-time fluoroscopic MRI within said patient anatomy of said interventional device during said operation of said means for re-introducing.
Claim 26
Dependent Claim
46 words
An MRI apparatus comprising: an open structure background MRI magnet allowing lateral access to a patient imaging volume for performance of interventional procedures; and means for superimposing a prior saved image of a first physical field with real-time fluoroscopic MR images of a second physical field.
Claim 27
Dependent Claim
46 words
An MRI apparatus comprising: an open structure background MRI magnet allowing lateral access to a patient imaging volume for performance of interventional procedures; and means for superimposing a prior saved image of a first physical field with real-time fluoroscopic MR images of a second physical field.
Claim 28
Dependent Claim
25 words
An MRI apparatus as in claim 22 wherein said first physical field comprises a patient anatomy and said second physical field comprises an interventional device.
Claim 29
Dependent Claim
25 words
An MRI apparatus as in claim 22 wherein said first physical field comprises an interventional device and said second physical field comprises a patient anatomy.
Claim 30
Dependent Claim
33 words
An MRI apparatus as in claim 22, 23 or 24 further comprising: means for generating real-time fluoroscopic MR images of said first physical field as it physically merges with said second physical field.
Claim 31
Dependent Claim
149 words
An MRI apparatus for facilitating the safe introduction of interventional devices into patient anatomy, said apparatus comprising: means for placing patient anatomy within the image volume of an MRI system; means for creating and saving an MR image of said patient anatomy; means for removing said patient anatomy from the image volume; means for locating a desired trajectory for an interventional device within said image volume while superimposing the saved MR image of said patient anatomy with real-time fluoroscopic MR images of the interventional device; means for removing said interventional device from the MR image of the patient anatomy while retaining an ability to retrace said desired trajectory; means for returning said patient anatomy to the image volume in substantial registry with its earlier position at the time the saved MR image was created; and means for introducing said interventional device into said patient anatomy along said desired trajectory.
Claim 32
Dependent Claim
149 words
An MRI apparatus for facilitating the safe introduction of interventional devices into patient anatomy, said apparatus comprising: means for placing patient anatomy within the image volume of an MRI system; means for creating and saving an MR image of said patient anatomy; means for removing said patient anatomy from the image volume; means for locating a desired trajectory for an interventional device within said image volume while superimposing the saved MR image of said patient anatomy with real-time fluoroscopic MR images of the interventional device; means for removing said interventional device from the MR image of the patient anatomy while retaining an ability to retrace said desired trajectory; means for returning said patient anatomy to the image volume in substantial registry with its earlier position at the time the saved MR image was created; and means for introducing said interventional device into said patient anatomy along said desired trajectory.
Claim 33
Dependent Claim
34 words
An MRI apparatus as in claim 26 including means for performing MRI fluoroscopy to provide substantially real time images of said patient anatomy and of said interventional device as it retraces said desired trajectory.
Claim 34
Dependent Claim
26 words
An MRI apparatus as in claim 26 wherein said interventional device is at least partly loaded with an MR-visible fluid when used to locate said trajectory.
Claim 35
Dependent Claim
26 words
An MRI apparatus as in claim 26 wherein said interventional device is at least partly surrounded by an MR-visible fluid when used to locate said trajectory.
Claim 36
Dependent Claim
41 words
An MRI apparatus as in claim 26 wherein said interventional device is mounted for movement within an adjustable guiding jig which can be adjusted to at least partially define said desired trajectory and to thereafter facilitate retracing of that same trajectory.
Claim 37
Dependent Claim
27 words
An MRI apparatus as in claim 26 wherein said interventional device is part of a stereotatic apparatus coordinated with a stereotatic frame affixed to the patient anatomy.
Claim 38
Dependent Claim
19 words
An MRI apparatus as in claim 26 wherein said interventional device is capable of withdrawing patient tissue for biopsy.
Claim 39
Dependent Claim
21 words
An MRI apparatus as in claim 26 wherein said interventional device capable of imparting treatment to tissues within said patient anatomy.
Claim 40
Dependent Claim
30 words
An MRI apparatus as in claim 26 including means for creating new MR images of the patient anatomy and superimposing same with the earlier saved image of the patient anatomy.
References Cited (Backward Citations)
US4674046A
Cited
US4994965A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-10-13 | 1996-04-13 | 1996-10-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-10-13 | 2000-04-13 | 2000-10-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-10-13 | 2004-04-13 | 2004-10-13 | $7700.00 | Window Closed / Lapsed |