US5149694A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Combination of tobramycin and dexamethasone for topical ophthalmic use
Assignee: Alcon Research LLC
•
Filing: 1989-11-22
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Granted: 1992-09-22
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Expires: 2009-11-22
Abstract
Abstract Disclosed are pharmaceutical compositions comprising tobramycin and dexamethasone for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for infection and control of inflammatory response for optimal wound healing and normalization of the eye.
Inventors
- 👤 Gerald D. Cagle
- 👤 Thomas O. McDonald
- 👤 Allan L. Rosenthal
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 02:32
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
48 words
A method of treating ophthalmic inflammation and infection which comprises administering topically to the affected eye of a human host a therapeutically effective amount of an ophthalmic pharmaceutical composition comprising an anti-inflammatory effective amount of dexamethasone; and anti-infective effective amount of tobramycin; and a pharmaceutically acceptable carrier therefor.
Claim 2
Independent Claim
48 words
A method of treating ophthalmic inflammation and infection which comprises administering topically to the affected eye of a human host a therapeutically effective amount of an ophthalmic pharmaceutical composition comprising an anti-inflammatory effective amount of dexamethasone; and anti-infective effective amount of tobramycin; and a pharmaceutically acceptable carrier therefor.
Claim 3
Dependent Claim
45 words
A method according to claim 1, wherein the combined concentration of the tobramycin and the dexamethasone is 0.01 to 2.0 percent by weight, and the ratio of the amount of tobramycin to the amount of dexamethasone is in the range of from 0.1:1.0 to 10.0:1.0.
Claim 4
Dependent Claim
28 words
A method according to claim 1, wherein the concentration of the tobramycin is 0.3 percent by weight and the concentration of the dexamethasone is 0.1 percent by weight.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-09-22 | 1996-03-23 | 1996-09-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-09-22 | 2000-03-23 | 2000-09-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-09-22 | 2004-03-23 | 2004-09-22 | $7700.00 | Window Closed / Lapsed |