US5149691A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
Assignee: CONNECTICUT A CORP OF CT, University of
•
Filing: 1991-03-12
•
Granted: 1992-09-22
•
Expires: 2011-03-12
Abstract
Abstract Disclosed is a method for the regeneration of tissue, the treatment of external wounds and the treatment of periodontal disease comprised of applying to the afflicted tissue a pharmaceutically effective amount of a composition comprised of platelet-derived growth factor and dexamethasone.
Inventors
- 👤 Robert B. Rutherford
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 23:02
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/18; A61K38/1858; A61P; A61P1/00; A61P1/02; A61P43/00
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
32 words
A method for promoting regeneration and repair of dental tissue in a mammal comprising: applying to said tissue a therapeutically effective amount of a composition comprising platelet-derived growth factor (PDGF) and dexamethasone.
Claim 2
Independent Claim
32 words
A method for promoting regeneration and repair of dental tissue in a mammal comprising: applying to said tissue a therapeutically effective amount of a composition comprising platelet-derived growth factor (PDGF) and dexamethasone.
Claim 3
Dependent Claim
10 words
The method of claim 1, wherein the tissue is epithelium.
Claim 4
Dependent Claim
12 words
The method of claim 1, wherein the tissue is cartilage or bone.
Claim 5
Dependent Claim
18 words
The method of claim 1 wherein the composition of PDGF and dexamethasone further comprises a pharmaceutically acceptable carrier.
Claim 6
Dependent Claim
23 words
The method of claim 4, wherein the pharmaceutically acceptable carrier is selected from a group consisting of creams, ointments, gels and collagen matrix.
Claim 7
Independent Claim
37 words
A method for promoting healing of an external wound in the dental tissue of a mammal comprising: applying to said external wound a therapeutically effective amount of a composition comprised of platelet-derived growth factor (PDGF) and dexamethasone.
Claim 8
Independent Claim
37 words
A method for promoting healing of an external wound in the dental tissue of a mammal comprising: applying to said external wound a therapeutically effective amount of a composition comprised of platelet-derived growth factor (PDGF) and dexamethasone.
Claim 9
Dependent Claim
10 words
The method of claim 6, wherein the tissue is epithelium.
Claim 10
Independent Claim
34 words
A method for regenerating dental bone or cartilage tissue of a mammal comprising: applying to said dental cartilage or bone a therapeutically effective amount of a composition of platelet-derived growth factor (PDGF) and dexamethasone.
Claim 11
Independent Claim
34 words
A method for regenerating dental bone or cartilage tissue of a mammal comprising: applying to said dental cartilage or bone a therapeutically effective amount of a composition of platelet-derived growth factor (PDGF) and dexamethasone.
Claim 12
Independent Claim
36 words
A method for treating gum disease or periodontal ligament afflicted with periodontal disease comprising: applying to the gum tissue or periodontal ligament a therapeutically effective amount of a composition comprising platelet-derived growth factor (PDGF) and dexamethasone.
Claim 13
Independent Claim
36 words
A method for treating gum disease or periodontal ligament afflicted with periodontal disease comprising: applying to the gum tissue or periodontal ligament a therapeutically effective amount of a composition comprising platelet-derived growth factor (PDGF) and dexamethasone.
Claim 14
Dependent Claim
11 words
The method of claim 9, further comprising a pharmaceutically acceptable carrier.
Claim 15
Dependent Claim
22 words
The method of claim 10 wherein the pharmaceutically acceptable carrier is selected from the consisting of creams, ointments, gels and collagen matrix.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-09-22 | 1996-03-23 | 1996-09-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-09-22 | 2000-03-23 | 2000-09-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-09-22 | 2004-03-23 | 2004-09-22 | $7700.00 | Window Closed / Lapsed |