US5147529A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for automatically processing magnetic solid phase reagents
Assignee: Siemens Healthcare Diagnostics Inc
•
Filing: 1988-08-10
•
Granted: 1992-09-15
•
Expires: 2008-08-10
Abstract
Abstract Magnetic particles used as a solid support are placed in reaction vessels and stepped sequentially past successive magnets for separation.
Inventors
- 👤 Ching-Cherng Lee
- 👤 James E. Davis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 15:35
CPC Classifications
B; B03; B03C; B03C1/00; G; G01; G01N; G01N35/00; G01N35/02; G01N35/021; B03C1/005; B03C1/01; B03C1/02; B03C1/28; B03C1/288; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54313; G01N33/54326; B03C2201/00; B03C2201/26; G01N35/0098; Y; Y10; Y10T; Y10T436/00; Y10T436/11; Y10T436/111666; Y10T436/113332; Y10T436/25; Y10T436/25375
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
79 words
An automatic method for separating particles from liquid dispersions of such particles disposed in a plurality of reaction vessels, the particles being responsive to a magnetic field comprising the steps of: transporting the vessels to a plurality of processing positions, and subjecting each of the vessels at at least two consecutive processing positions, to a magnetic field for a dwell time at each position less than that required to effect a complete separation of the particles from the dispersion.
Claim 2
Dependent Claim
79 words
An automatic method for separating particles from liquid dispersions of such particles disposed in a plurality of reaction vessels, the particles being responsive to a magnetic field comprising the steps of: transporting the vessels to a plurality of processing positions, and subjecting each of the vessels at at least two consecutive processing positions, to a magnetic field for a dwell time at each position less than that required to effect a complete separation of the particles from the dispersion.
Claim 3
Dependent Claim
45 words
The method of claim 1 wherein the vessels have a longitudinal axis and includes the steps of: orienting the vessels longitudinal axes vertically while subjected to the magnetic field, and applying the magnetic field to different heights, relative to the longitudinal axis of the vessel.
Claim 4
Dependent Claim
19 words
The method of claim 2 wherein the magnetic field is applied in opposite senses at the consecutive processing positions.
Claim 5
Dependent Claim
31 words
The method of claim 3 which includes the step of subjecting the vessels at the last of the selected processing positions to a stronger magnetic field than at the remaining positions.
Claim 6
Dependent Claim
20 words
The method of claim 1 wherein the magnetic field is applied in opposite senses at the selected consecutive processing positions.
Claim 7
Dependent Claim
20 words
The method of claim 1 wherein the transporting means transports the vessels in a stepwise manner to each processing position.
Claim 8
Dependent Claim
52 words
The method of claim 6 wherein the vessels have a longitudinal axis and includes the steps of: orienting the vessels longitudinal axes vertically while subjected to the magnetic field, and applying the magnetic field to different heights, at at least two consecutive processing positions, relative to the longitudinal axis of the vessel.
Claim 9
Dependent Claim
20 words
The method of claim 7 wherein the magnetic field is applied in opposite senses at the selected consecutive processing positions.
Claim 10
Dependent Claim
20 words
The method of claim 6 wherein the magnetic field is applied in opposite senses at the selected consecutive processing positions.
References Cited (Backward Citations)
US3953997A
Cited
US4066537A
Cited
US4628037A
Cited
US4698302A
Cited
US4908186A
Cited
US4661408A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-09-15 | 1996-03-16 | 1996-09-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-09-15 | 2000-03-16 | 2000-09-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-09-15 | 2004-03-16 | 2004-09-15 | $7700.00 | Window Closed / Lapsed |