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US5146917A Expired / Lapsed US ⏱️ 0.0 years remaining

Fibre-optic apparatus for the photodynamic treatment of tumors

Assignee: Novartis Corp
•
Filing: 1991-01-04
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Granted: 1992-09-15
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Expires: 2011-01-04
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Abstract

Abstract A bronchoscope has a fibre-optic apparatus for the photodynamic treatment of tumors in the region of the furcate branches of the bronchi, the divergent pencil of rays (13), which emerges from the end face (9) of an optical fibre, striking a lens arrangement consisting of two microlenses (14,15) which, owing to the spherical aberration, deflect edge rays (23) in the divergent pencil of rays (13) of the optical fibre (8) in such a manner that a homogeneous sharp-edged emerging pencil of rays is formed.

Inventors

  • 👤 Georges Wagnieres
  • 👤 Hubert van den Bergh
  • 👤 Philippe Monnier

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 23:11
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/06; A61N5/0613; A61N5/062; A61N5/0601

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 290 words
A fibre-optic apparatus for the photodynamic treatment of tumours in a patient, which apparatus has an optical fibre connected to a laser for conveying light to a site of the tumour in a patient, wherein first and second lenses comprising a pair of lenses (14, 15) which are similar plano-convex microlenses (14, 15), each microlens having a planar side and a convex side; a focal length which locates a focal point relative to the lens; a central ray axis; and a diameter the focal length of which is smaller than the diameter thereof, said microlenses being arranged such that the convex sides (19, 20) thereof are facing each other and which are at a distance from one another that is smaller than the focal length of the microlenses (14, 15), and including means for locating said microlenses coaxially with respect to a light (13)-emitting end face (9) of the fibre (8) and are so adjusted and have a spherical aberration such that edge rays (23) having an angle of divergence (β) of a divergent pencil of light rays (23) emerging from the end face (9) of the fibre (8) are so greatly refracted by the first lens (14) of the lens pair, owing to the spherical aberration of said first lens (14), that, after traversing radially the central ray axis of the pair of lenses (14, 15) before the focal point (24'), said edge rays enter the convex side (20) of the second lens (15) of the lens pair (14, 15) at a site (25) lying diametrically opposite a site of emergence (26) from the convex side (19) of the first lens (14), as a result of which the angle of divergence (β) of the edge rays (23) is reduced.
Claim 2
Dependent Claim 290 words
A fibre-optic apparatus for the photodynamic treatment of tumours in a patient, which apparatus has an optical fibre connected to a laser for conveying light to a site of the tumour in a patient, wherein first and second lenses comprising a pair of lenses (14, 15) which are similar plano-convex microlenses (14, 15), each microlens having a planar side and a convex side; a focal length which locates a focal point relative to the lens; a central ray axis; and a diameter the focal length of which is smaller than the diameter thereof, said microlenses being arranged such that the convex sides (19, 20) thereof are facing each other and which are at a distance from one another that is smaller than the focal length of the microlenses (14, 15), and including means for locating said microlenses coaxially with respect to a light (13)-emitting end face (9) of the fibre (8) and are so adjusted and have a spherical aberration such that edge rays (23) having an angle of divergence (β) of a divergent pencil of light rays (23) emerging from the end face (9) of the fibre (8) are so greatly refracted by the first lens (14) of the lens pair, owing to the spherical aberration of said first lens (14), that, after traversing radially the central ray axis of the pair of lenses (14, 15) before the focal point (24'), said edge rays enter the convex side (20) of the second lens (15) of the lens pair (14, 15) at a site (25) lying diametrically opposite a site of emergence (26) from the convex side (19) of the first lens (14), as a result of which the angle of divergence (β) of the edge rays (23) is reduced.
Claim 3
Dependent Claim 39 words
An apparatus according to claim 1, wherein the end face (9) of the fibre (8) is arranged at a distance from the planar side (41) of the first lens (14) that is a multiple of the focal length thereof.
Claim 4
Dependent Claim 62 words
An apparatus according to claim 1, wherein the optical fibre (8) has a core diameter of 200 μm, a numerical aperture of 0.21; and is a distance of 3.2 mm from the first plano-convex microlens (14) the lenses (14, 15) being separated by a distance of 0.7 mm the diameter thereof being 1.5 mm and the focal length thereof being 1 mm.
Claim 5
Dependent Claim 23 words
An apparatus according to claim 1, wherein the lenses are made of flint glass having a refractive index of 1.876 at 630 nm.
Claim 6
Dependent Claim 53 words
An apparatus according to claim 1, wherein the apparatus contains a lens tube having a front and rear end and the pair of lenses consisting of the microlenses (14, 15) is arranged near the front end of a lens tube (3) in the rear end of which the optical fibre (8) is secured.
Claim 7
Dependent Claim 60 words
An apparatus according to claim 5, wherein the lens tube (3, 32) is surrounded by an air-supply tube (35) having a front end and between the lens tube (3, 32) and the air-supply tube (35) there are arranged air ducts (31, 37, 38) that open into air nozzles (30) formed on the front end (1) of the air-supply tube (35).

References Cited (Backward Citations)

US4017150A Cited
US4445892A Cited
US4551129A Cited
GB2154761A Cited
US4693244A Cited
US4660925A Cited
US4693556A Cited
US4842390A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-09-15 1996-03-16 1996-09-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-09-15 2000-03-16 2000-09-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-09-15 2004-03-16 2004-09-15 $7700.00 Window Closed / Lapsed

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