US5145769A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for cryopreserving blood vessels
Assignee: MEDICAL UNIVERSITY OF SOUTH CAROLINA 171 ASHLEY AVENUE CHARLESTON SOUTH CAROLINA A SOUTH CAROLINA CORP
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Filing: 1987-08-21
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Granted: 1992-09-08
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Expires: 2007-08-21
Abstract
Abstract A device for use in cryopreservation of blood vessels comprising a pair of styles insertable into the ends of a dissected blood vessel segment. The styles are mountable on a support track whereby the blood vessel can be distended and supported during cryopreservation procedures. Also disclosed is a freezing and thawing profile capable of maximizing endothelial cell survival. The use of chondroitin sulfate or similar compound is discussed as a novel cryoprotectant.
Inventors
- 👤 Robert T. McNally
- 👤 Cameron McCaa
- 👤 Kelvin G. M. Brockbank
- 👤 Albert E. Heacox
- 👤 Harvey L. Bank
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 19:32
CPC Classifications
A; A01; A01N; A01N1/00; A01N1/10; A01N1/16; A01N1/162; A01N1/12; A01N1/122; A01N1/125; A01N1/14
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
46 words
A composition comprising: i) a tissue storage medium comprising a cryoprotectively effective concentration of a cell penetrating cryoprotectant and a cryoprotectively effective concentration of a glycosaminoglycan, and ii) a segment of a blood vessel, wherein said segment of said blood vessel is submerged in said medium.
Claim 2
Dependent Claim
46 words
A composition comprising: i) a tissue storage medium comprising a cryoprotectively effective concentration of a cell penetrating cryoprotectant and a cryoprotectively effective concentration of a glycosaminoglycan, and ii) a segment of a blood vessel, wherein said segment of said blood vessel is submerged in said medium.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-09-08 | 1996-03-09 | 1996-09-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-09-08 | 2000-03-09 | 2000-09-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-09-08 | 2004-03-09 | 2004-09-08 | $7700.00 | Window Closed / Lapsed |