US5141752A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Delayed drug delivery device
Assignee: Alza Corp
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Filing: 1991-07-25
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Granted: 1992-08-25
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Expires: 2011-07-25
Abstract
Abstract A dosage form comprising (1) an immediately available dose of a beneficial drug followed by a timed delayed dose of drug, or (2) a timed delayed dose of drug.
Inventors
- 👤 Atul D. Ayer
- 👤 Felix Theeuwes
- 👤 Patrick S. L. Wong
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 14:40
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
155 words
A dosage form for delivering a beneficial drug formulation to an environment of use, the dosage form comprising: (a) a wall comprising at least in part a semipermeable composition permeable to the passage of an external fluid present in the environment of use and substantially impermeable to the passage of a beneficial drug formulation, which wall surrounds and forms; (b) a compartment; (c) a drug formulation in the compartment that exhibits an osmotic pressure gradient across a semipermeable wall, which drug formulation produces at least one of a physiological, pharmacological, local and systemic effect in an animal; (d) means for delaying the delivery of the drug formulation up to 12 hours from the compartment, which means comprises a drug-free lamina that surrounds the drug formulation; and, (e) at least one exit means in the wall for communicating the exterior of the dosage form with the compartment for delivering the dosage formulation from the dosage form.
Claim 2
Dependent Claim
155 words
A dosage form for delivering a beneficial drug formulation to an environment of use, the dosage form comprising: (a) a wall comprising at least in part a semipermeable composition permeable to the passage of an external fluid present in the environment of use and substantially impermeable to the passage of a beneficial drug formulation, which wall surrounds and forms; (b) a compartment; (c) a drug formulation in the compartment that exhibits an osmotic pressure gradient across a semipermeable wall, which drug formulation produces at least one of a physiological, pharmacological, local and systemic effect in an animal; (d) means for delaying the delivery of the drug formulation up to 12 hours from the compartment, which means comprises a drug-free lamina that surrounds the drug formulation; and, (e) at least one exit means in the wall for communicating the exterior of the dosage form with the compartment for delivering the dosage formulation from the dosage form.
References Cited (Backward Citations)
US4842867A
Cited
US4948592A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-25 | 1996-02-24 | 1996-08-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-25 | 2000-02-24 | 2000-08-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-25 | 2004-02-24 | 2004-08-25 | $7700.00 | Window Closed / Lapsed |