US5136080A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Nitrile compounds
Assignee: Wellcome Foundation Ltd
•
Filing: 1990-06-05
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Granted: 1992-08-04
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Expires: 2010-06-05
Abstract
Abstract A class of substituted phenylpyrimidine compounds are disclosed which are potent inhibitors of the excitatory amino acid, glutamate. Such compounds are useful in the treatment or prevention of a range of CNS disorders including cerebral ischaemic damage and epilepsy.
Inventors
- 👤 Alistair A. Miller
- 👤 Malcolm S. Nobbs
- 👤 Richard M. Hyde
- 👤 Michael John
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 17:19
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/32; C07D239/42; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61K31/506; A61K31/535; A61K31/5375; A61K31/5377; C07C; C07C255/00; C07C255/49; C07C255/54; C07C255/56; C07D239/46; C07D239/47; C07D239/48; C07D239/50; C07D239/56; C07D239/58
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
10 words
A compound selected from the group 2-(2,3,5-trichlorophenyl)-4,4,4-trifluoro-3-methoxybut-2-enonitrile; 2-(2,3,5-trichlorophenyl)-4-methoxy-3-oxobutyronitrile; or 2-(2,3,5-trichlorophenyl)-3-methoxy-acrylonitrile.
Claim 2
Dependent Claim
10 words
A compound selected from the group 2-(2,3,5-trichlorophenyl)-4,4,4-trifluoro-3-methoxybut-2-enonitrile; 2-(2,3,5-trichlorophenyl)-4-methoxy-3-oxobutyronitrile; or 2-(2,3,5-trichlorophenyl)-3-methoxy-acrylonitrile.
Claim 3
Dependent Claim
3 words
The compound 2-(2,3,5-trichlorophenyl)-4,4,4-trifluoro-3-methoxybut-2-enonitrile.
Claim 4
Dependent Claim
3 words
The compound 2-(2,3,5-trichlorophenyl)-4,4,4-trifluoro-3-methoxybut-2-enonitrile.
Claim 5
Dependent Claim
3 words
The compound 2-(2,3,5-trichlorophenyl)-4-methoxy-3-oxobutyronitrile.
Claim 6
Dependent Claim
3 words
The compound 2-(2,3,5-trichlorophenyl)-4-methoxy-3-oxobutyronitrile.
Claim 7
Dependent Claim
3 words
The compound 2-(2,3,5-trichlorophenyl)-3-methoxy-acrylonitrile.
Claim 8
Dependent Claim
3 words
The compound 2-(2,3,5-trichlorophenyl)-3-methoxy-acrylonitrile.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-04 | 1996-02-03 | 1996-08-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-04 | 2000-02-03 | 2000-08-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-04 | 2004-02-03 | 2004-08-04 | $7700.00 | Window Closed / Lapsed |