US5135498A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Controlled release infusion device
Assignee: PharMetrix Corp
•
Filing: 1990-04-02
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Granted: 1992-08-04
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Expires: 2010-04-02
Abstract
Abstract A means for elimination or compression of trapped air spaces in osmotically powered pumps is disclosed in which the housing of the pump is constructed of movable portions so that movement of the said housing portions will force air out of the device or compress it to such an extent that activation of the pump will result in the minimum lag time between activation of the pump and infusate flow.
Inventors
- 👤 Robert J. Kam
- 👤 Rolf A. Faste
- 👤 Anthony J. Castro
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 09:37
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/142; A61M5/145; A61M5/148; A61M5/1483; Y; Y10; Y10S; Y10S128/00; Y10S128/12
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
167 words
A portable infusion device assembly comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment and, e. a first rigid housing in restraining relationship containing the aforesaid first pouch and in sliding relationship with a second housing f. a second rigid housing in restraining relationship containing the aforesaid second pouch and in sliding relationship with aforesaid first housing and, g. a means for initiating flow of infusate by forcibly moving aforesaid first and second housings in such a manner as to compel and maintain contact between aforesaid first and second pouches.
Claim 2
Dependent Claim
167 words
A portable infusion device assembly comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment and, e. a first rigid housing in restraining relationship containing the aforesaid first pouch and in sliding relationship with a second housing f. a second rigid housing in restraining relationship containing the aforesaid second pouch and in sliding relationship with aforesaid first housing and, g. a means for initiating flow of infusate by forcibly moving aforesaid first and second housings in such a manner as to compel and maintain contact between aforesaid first and second pouches.
Claim 3
Dependent Claim
153 words
A portable infusion device assembly comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment and, e. a rigid housing containing the aforesaid first pouch, second pouch and power source and in restraining relationship with the aforesaid first and second pouches, and f. a means for initiating flow of infusate by forcibly moving aforesaid first and second housings in such a manner as to compel and maintain contact between aforesaid first and second pouches and power source.
Claim 4
Dependent Claim
153 words
A portable infusion device assembly comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment and, e. a rigid housing containing the aforesaid first pouch, second pouch and power source and in restraining relationship with the aforesaid first and second pouches, and f. a means for initiating flow of infusate by forcibly moving aforesaid first and second housings in such a manner as to compel and maintain contact between aforesaid first and second pouches and power source.
Claim 5
Dependent Claim
44 words
The device according to claim 1 where: a. the pressure generating means is comprised of: an osmagent and, a liquid permeant and, b. the rate controlling means is comprised of a semipermeable membrane and, c. the driving fluid is produced when permeant contacts osmagent.
Claim 6
Dependent Claim
49 words
The device according to claim 1 where: a. the pressure generating means is comprised of: a gas generating electrolytic cell, b. the rate controlling means is a electrical circuit operated is such a manner as to control the rate of gas formation and, c. the operating medium is gaseous.
Claim 7
Dependent Claim
47 words
The device according to claim 1 where: a. the pressure generating means is comprised of: a gas under pressure, b. the rate controlling means is a valve operated is such a manner as to control the rate of gas flow and, c. the operating medium is gaseous.
Claim 8
Dependent Claim
59 words
The device according to claim 1 where: a. the pressure generating means is comprised of: a mechanical means for increasing the pressure of the pressure-transmitting pouch, b. the rate controlling means is obtained by operating the aforesaid mechanical means in such a manner so as to control the rate of pressure formation and, c. the operating medium is liquid.
Claim 9
Dependent Claim
59 words
The device according to claim 1 where: a. the pressure generating means is comprised of: a mechanical means for increasing the pressure of the pressure-transmitting pouch, b. the rate controlling means is obtained by operating the aforesaid mechanical means in such a manner so as to control the rate of pressure formation and, c. the operating medium is gaseous.
Claim 10
Dependent Claim
44 words
The device according to claim 2 where: a. the pressure generating means is comprised of: an osmagent and, a liquid permeant and, b. the rate controlling means is comprised of a semipermeable membrane and, c. the driving fluid is produced when permeant contacts osmagent.
Claim 11
Dependent Claim
49 words
The device according to claim 2 where: a. the pressure generating means is comprised of: a gas generating electrolytic cell, b. the rate controlling means is a electrical circuit operated is such a manner as to control the rate of gas formation and, c. the operating medium is gaseous.
Claim 12
Dependent Claim
47 words
The device according to claim 2 where: a. the pressure generating means is comprised of: a gas under pressure, b. the rate controlling means is a valve operated is such a manner as to control the rate of gas flow and, c. the operating medium is gaseous.
Claim 13
Dependent Claim
59 words
The device according to claim 2 where: a. the pressure generating means is comprised of: a mechanical means for increasing the pressure of the pressure-transmitting pouch, b. the rate controlling means is obtained by operating the aforesaid mechanical means in such a manner so as to control the rate of pressure formation and, c. the operating medium is liquid.
Claim 14
Dependent Claim
59 words
The device according to claim 2 where: a. the pressure generating means is comprised of: a mechanical means for increasing the pressure of the pressure-transmitting pouch, b. the rate controlling means is obtained by operating the aforesaid mechanical means in such a manner so as to control the rate of pressure formation and, c. the operating medium is gaseous.
Claim 15
Independent Claim
123 words
A method for infusing a patient, comprising connection of said patient to a portable infusion device, said device comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment, e. a rigid housing in restraining relationship containing the aforesaid first and second pouches and, f. activating said device.
Claim 16
Independent Claim
123 words
A method for infusing a patient, comprising connection of said patient to a portable infusion device, said device comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment, e. a rigid housing in restraining relationship containing the aforesaid first and second pouches and, f. activating said device.
Claim 17
Independent Claim
185 words
A method for infusing a patient, comprising connection of said patient to a portable infusion device, said device comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment and, e. a rigid housing in restraining relationship containing the aforesaid first pouch, second pouch and power source and in restraining relationship with the aforesaid first and second pouches, f. a means for initiating flow of infusate by forcibly moving aforesaid first and second housings in such a manner as to compel and maintain contact between aforesaid first and second pouches and power source. g. initiating infusate flow by forcibly moving aforesaid first and second housings and, h. activating said device.
Claim 18
Independent Claim
185 words
A method for infusing a patient, comprising connection of said patient to a portable infusion device, said device comprising: a. a first pouch containing infusate and a dispensing nozzle, b. a second pouch containing a driving medium in pressure transmitting relationship to the aforesaid first pouch, c. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid generating means, a rate controlling means for regulating the volume change of the aforesaid first pouch, d. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment and, e. a rigid housing in restraining relationship containing the aforesaid first pouch, second pouch and power source and in restraining relationship with the aforesaid first and second pouches, f. a means for initiating flow of infusate by forcibly moving aforesaid first and second housings in such a manner as to compel and maintain contact between aforesaid first and second pouches and power source. g. initiating infusate flow by forcibly moving aforesaid first and second housings and, h. activating said device.
Claim 19
Independent Claim
93 words
A method for facilitating infusate flow from an infusion device comprising: a. an infusate compartment, b. a dispensing nozzle for delivering infusate from said infusate compartment, c. a force means for generating and applying continuous pressure to said infusate compartment sufficient to cause infusate flow, d. a housing in restraining relationship to said infusate compartment and force means comprised of portions in moveable relationship in that movement of said portions will cause elimination or compression of trapped air spaces so that activation of the force means will produce infusate flow without significant delay.
Claim 20
Independent Claim
93 words
A method for facilitating infusate flow from an infusion device comprising: a. an infusate compartment, b. a dispensing nozzle for delivering infusate from said infusate compartment, c. a force means for generating and applying continuous pressure to said infusate compartment sufficient to cause infusate flow, d. a housing in restraining relationship to said infusate compartment and force means comprised of portions in moveable relationship in that movement of said portions will cause elimination or compression of trapped air spaces so that activation of the force means will produce infusate flow without significant delay.
Claim 21
Dependent Claim
20 words
A method according to claim 15 where trapped air space is eliminated or compressed before activation of the force means.
Claim 22
Dependent Claim
21 words
A method according to claim 15 where trapped air space is eliminated or compressed simultaneous with activation of the force means.
Claim 23
Dependent Claim
21 words
A method according to claim 15 where trapped air space is eliminated or compressed shortly after activation of the force means.
Claim 24
Dependent Claim
112 words
A portable infusion device assembly comprising: a. dispensing nozzle. b. infusate, c. a driving medium in pressure transmitting relationship to the aforesaid infusate, d. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid pressure generating means, a rate controlling means for regulating the volume change of the aforesaid infusate, e. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment, f. a rigid housing in restraining relationship containing the aforesaid infusate and pressure generating means and, g. a means for displacing or compressing contained air spaces in the aforesaid rigid housing.
Claim 25
Dependent Claim
112 words
A portable infusion device assembly comprising: a. dispensing nozzle. b. infusate, c. a driving medium in pressure transmitting relationship to the aforesaid infusate, d. an integral power source comprising: a pressure generating means for generating pressure in aforesaid driving medium, an activating means for initiating the action of the aforesaid pressure generating means, a rate controlling means for regulating the volume change of the aforesaid infusate, e. a connecting means for attaching the aforesaid dispensing nozzle to the object of treatment, f. a rigid housing in restraining relationship containing the aforesaid infusate and pressure generating means and, g. a means for displacing or compressing contained air spaces in the aforesaid rigid housing.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-04 | 1996-02-03 | 1996-08-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-04 | 2000-02-03 | 2000-08-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-04 | 2004-02-03 | 2004-08-04 | $7700.00 | Window Closed / Lapsed |